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of 9
pro vyhledávání: '"Nigel Vivian"'
Autor:
Lidia Pérez, Robin Lovell-Badge, Silvia K. Nicolis, Larysa H. Pevny, Ariel A. Avilion, Nigel Vivian
Publikováno v:
Genes & Development. 17:126-140
Each cell lineage specified in the preimplantation mammalian embryo depends on intrinsic factors for its development, but there is also mutual interdependence between them. OCT4 is required for the ICM/epiblast lineage, and at transient high levels f
Autor:
Robin Lovell-Badge, Andrea Münsterberg, Daniel Guerrier, Charlotte Beau, Nigel Vivian, David W. Dresser
Publikováno v:
Molecular Reproduction and Development. 59:256-264
Anti-Mullerian hormone (AMH) is a member of the TGF-β family which elicits its main action during male sex differentiation. This hormone is probably the most convenient marker of Sertoli cell differentiation and maturation throughout testicular deve
Autor:
John Gubbay, Androulla Economou, David C. Jackson, Robin Lovell-Badge, Peter N. Goodfellow, Nigel Vivian
Publikováno v:
Proceedings of the National Academy of Sciences. 89:7953-7957
The testis-determining gene Sry is located on the short arm of the mouse Y chromosome in a region known to have undergone duplications and rearrangements in comparison with the equivalent portion of the human Y chromosome. Detailed analysis of the Sr
Autor:
John Gubbay, Jérôme Collignon, Androulla Economou, Andrea Münsterberg, Blanche Capel, Peter N. Goodfellow, Peter Koopman, Nigel Vivian, Robin Lovell-Badge
Publikováno v:
Scopus-Elsevier
A gene mapping to the sex-determining region of the mouse Y chromosome is deleted in a line of XY female mice mutant for Tdy, and is expressed at a stage during male gonadal development consistent with its having a role in testis determination. This
Autor:
Sohaila Rastan, Elizabeth M. Simpson, Colin E. Bishop, Carol Rasberry, Bruce M. Cattanach, Robin Lovell-Badge, Julian Dyson, Nigel Vivian, Blanche Capel
Publikováno v:
Nature genetics. 5(3)
An approach designed to map and generate mutations in the region of the short arm of the mouse Y chromosome, known to be involved in sex determination and spermatogenesis, is described. This relies on homologous Yp-Sxra pairing and asymmetrical excha
Publikováno v:
Nature. 351(6322)
The initiation of male development in mammals requires one or more genes on the Y chromosome. A recently isolated gene, termed SRY in humans and Sry in mouse, has many of the genetic and biological properties expected of a Y-located testis-determinin
Previous work in transfected cell lines and in nuclear extracts has led to the identification of two cis-acting elements important for transcription of the human alpha-1-antitrypsin (A1AT) gene, which bind to two liver specific trans-acting factors,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92fdfc83f0711cdc4bd8bd579b1fe895
http://hdl.handle.net/11588/136775
http://hdl.handle.net/11588/136775
Autor:
Nigel Vivian
Publikováno v:
Educational Management & Administration. 16:230-231
Publikováno v:
Trends in Genetics. 4:325-325