Zobrazeno 1 - 10
of 525
pro vyhledávání: '"Nigel S. SCRUTTON"'
Autor:
Erik K. R. Hanko, Christopher J. Robinson, Sahara Bhanot, Adrian J. Jervis, Nigel S. Scrutton
Publikováno v:
Microbial Cell Factories, Vol 23, Iss 1, Pp 1-12 (2024)
Abstract Background Flavonoids are a structurally diverse group of secondary metabolites, predominantly produced by plants, which include a range of compounds with pharmacological importance. Pinocembrin is a key branch point intermediate in the bios
Externí odkaz:
https://doaj.org/article/1b21593da9fc404f9360ccceb4261f3d
Publikováno v:
Microbial Cell Factories, Vol 23, Iss 1, Pp 1-15 (2024)
Abstract Background Achieving cost-competitiveness remains challenging for industrial biomanufacturing. With whole-cell biocatalysis, inefficiency presents when individual cells vary in their production levels. The problem exacerbates when the basis
Externí odkaz:
https://doaj.org/article/266572d8298942f98ea7ecab435a35c9
Autor:
Shaowei Zhang, Laura N. Jeffreys, Harshwardhan Poddar, Yuqi Yu, Chuanyang Liu, Kaylee Patel, Linus O. Johannissen, Lingyun Zhu, Matthew J. Cliff, Cunyu Yan, Giorgio Schirò, Martin Weik, Michiyo Sakuma, Colin W. Levy, David Leys, Derren J. Heyes, Nigel S. Scrutton
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Photoreceptor proteins utilise chromophores to sense light and trigger a biological response. The discovery that adenosylcobalamin (or coenzyme B12) can act as a light-sensing chromophore heralded a new field of B12-photobiology. Although mi
Externí odkaz:
https://doaj.org/article/a0f44c530eda465fa74001ba20e7cc49
Autor:
Matthew Faulkner, Robin Hoeven, Paul P. Kelly, Yaqi Sun, Helen Park, Lu-Ning Liu, Helen S. Toogood, Nigel S. Scrutton
Publikováno v:
Biotechnology for Biofuels and Bioproducts, Vol 16, Iss 1, Pp 1-14 (2023)
Abstract Background Production of relatively low value, bulk commodity chemicals and fuels by microbial species requires a step-change in approach to decrease the capital and operational costs associated with scaled fermentation. The utilisation of t
Externí odkaz:
https://doaj.org/article/8169c2a43dd743c9a183c7bfd0123248
Autor:
Harshwardhan Poddar, Ronald Rios-Santacruz, Derren J. Heyes, Muralidharan Shanmugam, Adam Brookfield, Linus O. Johannissen, Colin W. Levy, Laura N. Jeffreys, Shaowei Zhang, Michiyo Sakuma, Jacques-Philippe Colletier, Sam Hay, Giorgio Schirò, Martin Weik, Nigel S. Scrutton, David Leys
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract CarH is a coenzyme B12-dependent photoreceptor involved in regulating carotenoid biosynthesis. How light-triggered cleavage of the B12 Co-C bond culminates in CarH tetramer dissociation to initiate transcription remains unclear. Here, a seri
Externí odkaz:
https://doaj.org/article/001606f7b0874be9a4255441eb03bd98
Publikováno v:
Microbial Biotechnology, Vol 16, Iss 2, Pp 307-321 (2023)
Abstract Halomonas bluephagenesis TD1.0 was engineered to produce the biofuel propane, bioplastic poly‐3‐hydroxybutyrate (PHB), and biochemicals mandelate and hydroxymandelate in a single, semi‐continuous batch fermentation under non‐sterile
Externí odkaz:
https://doaj.org/article/39b4b04f344543ab917b77edbaa9fe02
Autor:
Matthew Russell, Andrew Currin, William Rowe, Guo-Qiang Chen, Perdita Barran, Nigel S. Scrutton
Publikováno v:
Scientific Data, Vol 9, Iss 1, Pp 1-9 (2022)
Measurement(s) Genome • Proteomic Profile Technology Type(s) PacBio Sequel System • nanoflow liquid chromatography-electrospray ionisation mass spectrometry Sample Characteristic - Organism Halomonas sp. TD01
Externí odkaz:
https://doaj.org/article/93575e06332d4a3386ad282de06fbed2
Publikováno v:
Biotechnology for Biofuels, Vol 14, Iss 1, Pp 1-17 (2021)
Abstract Current industrial bioethanol production by yeast through fermentation generates carbon dioxide. Carbon neutral bioethanol production by cyanobacteria uses biological fixation (photosynthesis) of carbon dioxide or other waste inorganic carbo
Externí odkaz:
https://doaj.org/article/707168e8b04141de9de781028473e5eb
Autor:
Emmanuel Wolde-Michael, Aled D. Roberts, Derren J. Heyes, Ahu G. Dumanli, Jonny J. Blaker, Eriko Takano, Nigel S. Scrutton
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract The remarkable camouflage capabilities of cephalopods have inspired many to develop dynamic optical materials which exploit certain design principles and/or material properties from cephalopod dermal cells. Here, the angle-dependent optical
Externí odkaz:
https://doaj.org/article/98fad925ef36449ba62e72b02ad43ee5
A plasmid toolset for CRISPR‐mediated genome editing and CRISPRi gene regulation in Escherichia coli
Autor:
Adrian J. Jervis, Erik K.R. Hanko, Mark S. Dunstan, Christopher J. Robinson, Eriko Takano, Nigel S. Scrutton
Publikováno v:
Microbial Biotechnology, Vol 14, Iss 3, Pp 1120-1129 (2021)
Summary CRISPR technologies have become standard laboratory tools for genetic manipulations across all kingdoms of life. Despite their origins in bacteria, the development of CRISPR tools for engineering bacteria has been slower than for eukaryotes;
Externí odkaz:
https://doaj.org/article/93c6321b959a442383f2e02ce5235557