Zobrazeno 1 - 10
of 453
pro vyhledávání: '"Nigel S. Key"'
Publikováno v:
Haematologica, Vol 999, Iss 1 (2024)
Not available.
Externí odkaz:
https://doaj.org/article/60ae9fe1668a4357a80d9ebdf2799be3
Autor:
Mayck Silva Barbosa, Franciele de Lima, Carla Roberta Peachazepi Moraes, Ivanio Teixeira Borba-Junior, Stephany Cares Huber, Irene Santos, Bruna Bombassaro, Sergio San Juan Dertkigil, Anton Ilich, Nigel S. Key, Joyce M. Annichino-Bizzacchi, Fernanda Andrade Orsi, Eli Mansour, Licio A. Velloso, Erich Vinicius De Paula
Publikováno v:
Frontiers in Medicine, Vol 11 (2024)
Coagulation activation in immunothrombosis involves various pathways distinct from classical hemostasis, offering potential therapeutic targets to control inflammation-induced hypercoagulability while potentially sparing hemostasis. The Angiopoietin/
Externí odkaz:
https://doaj.org/article/d0c2997deb6d4891849f15b35a464aa5
Autor:
Sarah C. Skinner, Vimal K. Derebail, Caroline J. Poulton, Donna C. Bunch, Prabir Roy-Chaudhury, Nigel S. Key
Publikováno v:
Kidney Medicine, Vol 3, Iss 4, Pp 607-618 (2021)
Individuals receiving long-term hemodialysis are at increased risk of developing cardiovascular disease (CVD). Traditional cardiovascular risk factors do not fully explain the high CVD risk in this population. During hemodialysis, blood interacts wit
Externí odkaz:
https://doaj.org/article/6af09f2881ce4fbc8b2790fd950740c2
Autor:
Sarah Skinner, Eric D. Ryan, Harry C. Stafford, Robert G. McMurray, Nigel S. Key, Micah J. Mooberry
Publikováno v:
eJHaem, Vol 1, Iss 1, Pp 251-254 (2020)
Abstract This exploratory study evaluated the effect of intense exercise on biomarkers of inflammation and coagulation activation in subjects with and without sickle cell trait (SCT). Fifteen healthy African American men (18‐35 years, 5 SCT, 10 con
Externí odkaz:
https://doaj.org/article/5dfbc59f5dbe4f6890dab15ca186146f
Autor:
Michael W. Henderson, Denis F. Noubouossie, Anton Ilich, Kathy J. Wilson, Rafal Pawlinski, Dougald M. Monroe, Nigel S. Key
Publikováno v:
Research and Practice in Thrombosis and Haemostasis, Vol 4, Iss 5, Pp 789-798 (2020)
Abstract Mounting evidence suggests that a variety of disease states are pathophysiologically related to activation of the contact system in vivo. The plasma contact system is composed of a cascade of serine proteases initiated by surface activation
Externí odkaz:
https://doaj.org/article/ef9e3503ced04bb0a1cc394be1c50aa8
Publikováno v:
Research and Practice in Thrombosis and Haemostasis, Vol 4, Iss 4, Pp 518-523 (2020)
Abstract The coronavirus disease 2019 (COVID‐19) pandemic is becoming one of the largest global public health crises in modern history. The race for an effective drug to prevent or treat the infection is the highest priority among health care provi
Externí odkaz:
https://doaj.org/article/7db446f535f648a38ff66c60f037add3
Publikováno v:
Research and Practice in Thrombosis and Haemostasis, Vol 4, Iss 4, Pp 636-643 (2020)
Abstract Introduction We conducted a longitudinal study in patients with pancreatic and colorectal cancer. We determined the effect of chemotherapy on extracellular vesicle tissue factor (EVTF) activity and the association of plasma EVTF activity wit
Externí odkaz:
https://doaj.org/article/2e5fccf8be5f4d2a91aa14bdc8e7c28a
Autor:
Anton Ilich, Denis F. Noubouossie, Michael Henderson, Patrick Ellsworth, Kathleen F. Molitor, Elena Campello, Shannon Meeks, Amy Dunn, Myung S. Park, Rafal Pawlinski, Paolo Simioni, Amy Shapiro, Nigel S. Key
Publikováno v:
Research and Practice in Thrombosis and Haemostasis, Vol 4, Iss 1, Pp 46-53 (2020)
Abstract Numerous methods for evaluation of global fibrinolytic activity in whole blood or plasma have been proposed, with the majority based on tissue‐type plasminogen activator (t‐PA) addition to initiate fibrinolysis. We propose that such an a
Externí odkaz:
https://doaj.org/article/900e4ab51d71429d996a029b893c09f7
Autor:
Annette Von Drygalski, Adam Giermasz, Giancarlo Castaman, Nigel S. Key, Susan Lattimore, Frank W.G. Leebeek, Wolfgang Miesbach, Michael Recht, Alison Long, Robert Gut, Eileen K. Sawyer, Steven W. Pipe
Publikováno v:
Blood Advances, Vol 3, Iss 21, Pp 3241-3247 (2019)
Etranacogene dezaparvovec (AMT-061) is a recombinant AAV5 vector including a gene cassette containing the factor IX (FIX) Padua variant under the control of a liver-specific promoter. A phase 2b study was conducted to confirm that a single dose of 2
Externí odkaz:
https://doaj.org/article/66cb66c72e9147b78eee95d74a7a1df4
Autor:
Dana N. LeVine, Rachel E. Cianciolo, Keith E. Linder, Petra Bizikova, Adam J. Birkenheuer, Marjory B. Brooks, Abdelghaffar K. Salous, Shila K. Nordone, Dwight A. Bellinger, Henry Marr, Sam L. Jones, Thomas H. Fischer, Yu Deng, Marshall Mazepa, Nigel S. Key
Publikováno v:
Platelets, Vol 30, Iss 1, Pp 88-97 (2019)
Bleeding heterogeneity amongst patients with immune thrombocytopenia (ITP) is poorly understood. Platelets play a role in maintaining endothelial integrity, and variable thrombocytopenia-induced endothelial changes may influence bleeding severity. Pl
Externí odkaz:
https://doaj.org/article/d401d13a61cd44a6aa725f1e5272a207