Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Nigel S, Atkinson"'
Autor:
Nigel S. Atkinson
Publikováno v:
Cells, Vol 12, Iss 11, p 1508 (2023)
An understanding of neuroimmune signaling has become central to a description of how alcohol causes addiction and how it damages people with an AUD. It is well known that the neuroimmune system influences neural activity via changes in gene expressio
Externí odkaz:
https://doaj.org/article/3de7dc603f6d49afaa7dc99e98f7382c
Autor:
Nigel S Atkinson
Publikováno v:
Neuroscience Insights, Vol 16 (2021)
Intraspecies aggression is commonly focused on securing reproductive resources such as food, territory, and mates, and it is often males who do the fighting. In humans, individual acts of overt physical aggression seem maladaptive and probably repres
Externí odkaz:
https://doaj.org/article/cb4c9447d65c4396909c76e99cc261c0
Publikováno v:
eLife, Vol 9 (2020)
For decades, numerous researchers have documented the presence of the fruit fly or Drosophila melanogaster on alcohol-containing food sources. Although fruit flies are a common laboratory model organism of choice, there is relatively little understoo
Externí odkaz:
https://doaj.org/article/361e5a8e05774186afdd3bdd99ed06c0
Autor:
Thilini P. Wijesekera, Zheng Wu, Nicole P. Stephens, Rahul Godula, Linda Kao Lew, Nigel S. Atkinson
Publikováno v:
J Neurosci
NF-κB proteins are well known as transcription factors important in immune system activation. In this highly conserved role, they contribute to changes in behavior in response to infection and in response to a variety of other insults and experience
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18309002f4f3d75888331b3e61ad3698
https://europepmc.org/articles/PMC9034786/
https://europepmc.org/articles/PMC9034786/
Autor:
Maria E. Velez-Hernandez, Benjamin R. Troutwine, Nigel S. Atkinson, S. John Mihic, Linda Lew, Annie Park
Publikováno v:
Alcohol Clin Exp Res
BACKGROUND: NMDA receptors regulate synaptic plasticity and modulate a wide variety of behaviors. Mammalian NMDA receptors are inhibited by ethanol even at low concentrations. In mice, the F639A mutation in transmembrane domain 3 of the NR1 subunit r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2da8b55bbb169aeeaa6700911faf9240
https://doi.org/10.1111/acer.14215
https://doi.org/10.1111/acer.14215
Ancient association between cation leak channels and Mid1 proteins is conserved in fungi and animals
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 7 (2014)
Neuronal resting potential can tune the excitability of neural networks, affecting downstream behavior. Sodium leak channels (NALCN) play a key role in rhythmic behaviors by helping set, or subtly changing neuronal resting potential. The full complex
Externí odkaz:
https://doaj.org/article/4f41868919cf479db9e6158027128fe2
Autor:
Alfredo Ghezzi, Harish R Krishnan, Linda Lew, Francisco J Prado, Darryl S Ong, Nigel S Atkinson
Publikováno v:
PLoS Genetics, Vol 9, Iss 12, p e1003986 (2013)
Sustained or repeated exposure to sedating drugs, such as alcohol, triggers homeostatic adaptations in the brain that lead to the development of drug tolerance and dependence. These adaptations involve long-term changes in the transcription of drug-r
Externí odkaz:
https://doaj.org/article/0fd2e7fc6f58452883bf1fe37fce68e8
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e75549 (2013)
Drug tolerance and withdrawal are insidious responses to drugs of abuse; the first increases drug consumption while the second punishes abstention. Drosophila generate functional tolerance to benzyl alcohol sedation by increasing neural expression of
Externí odkaz:
https://doaj.org/article/393ab1ee3d8d455d999e86953a5283e9
Publikováno v:
eLife
eLife, Vol 9 (2020)
eLife, Vol 9 (2020)
For decades, numerous researchers have documented the presence of the fruit fly orDrosophila melanogasteron alcohol-containing food sources. Although fruit flies are a common laboratory model organism of choice, there is relatively little understood
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec3779b41bc2ad030164c435ee13c861
https://doi.org/10.7554/elife.59853
https://doi.org/10.7554/elife.59853