Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Nigel R. Burns"'
Autor:
Wendy J. Fowler, Mercedes Garcia-Valcarcel, Guy T. Layton, Michele Susanne Dr. Hill-Perkins, Gary Murphy, Donald J. Jeffries, Nigel R. Burns, David R. Harper, Alan J. Kingsman, Sally Adams
Publikováno v:
Virology. 214(2):531-540
The envelope proteins of varicella-zoster virus (VZV) are highly immunogenic and one of the most abundant is glycoprotein E (gE). However, its immunodominant regions and epitopes have not been identified. In this study, using human sera from individu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac27b295ab839b3b6ef000b06dce99ce
Autor:
G T Layton, T J French, E L Berrie, Sally Adams, Stephen J. Harris, J C Griffiths, A J Kingsman, Nigel R. Burns
Publikováno v:
Journal of Virology. 67:3191-3198
In attempts to increase the immunogenicity of recombinant antigens, a number of particulate antigen presentation systems have been developed. In this study, we used human immunodeficiency virus Gag particles as carriers for the human immunodeficiency
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f01cfe95b37dbd8702c68d3ed4543ab7
https://doi.org/10.1128/jvi.67.6.3191-3198.1993
https://doi.org/10.1128/jvi.67.6.3191-3198.1993
Publikováno v:
Trends in Biotechnology. 9:303-309
The manipulation of retrotransposon and retroviral particles to carry biologically active molecules is becoming feasible. In addition, recent experiments suggest that it may be possible to target these engineered particles to specific cell types. Thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::664f9677cf442d0bf4e5ecf6d6c8c139
https://doi.org/10.1016/0167-7799(91)90100-v
https://doi.org/10.1016/0167-7799(91)90100-v
Autor:
Stewart Craig, Nigel R. Burns, Susan M. Kingsman, Nigel Stenner, Sally Adams, Alan J. Kingsman, S. Mark H. Richardson, Sheena R. Lee
Publikováno v:
Journal of Molecular Biology. 216:207-211
We have developed a novel method for the expression and purification of p27, the major core protein of simian immunodeficiency virus. Circular dichroism measurements of purified p27 were used to determine the relative amounts of alpha-helix, beta-she
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df6aba9b067720024838de0089497143
https://doi.org/10.1016/s0022-2836(05)80308-0
https://doi.org/10.1016/s0022-2836(05)80308-0
The self-assembly properties of a protein encoded by the TYA gene of the yeast Ty element can be exploited to produce hybrid Ty-VLPs (virus-like particles) (1,2). There has been developed a series of expression vectors that allow the construction of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c2ae390297b51c01d9cbd99702798502
https://doi.org/10.1385/0-89603-191-8:277
https://doi.org/10.1385/0-89603-191-8:277
Autor:
Nicola Myers, Kevin J. Palmer, Sarah J. Butcher, Willem Tichelaar, Alan John Kingsman, Helen R. Saibil, Nigel R. Burns, Stephen D. Fuller
Publikováno v:
University of Helsinki
Journal of Virology
Journal of Virology
The virus-like particles (VLPs) produced by the yeast retrotransposon Ty1 are functionally related to retroviral cores. These particles are unusual in that they have variable radif. A paired mass-radius analysis of VLPs by scanning transmission elect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f20d425fea624760e215ff2ec807cd0
https://europepmc.org/articles/PMC191967/
https://europepmc.org/articles/PMC191967/
Publikováno v:
Annals of the New York Academy of Sciences. 754
The development of technologies to produce recombinant proteins for use in the pharmaceutical industry has made substantial advances, in particular in the area of generating antigens containing multiple copies of important immunological regions. One
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa62d6721a22cd2eec8dd29b4b7ec3be
https://pubmed.ncbi.nlm.nih.gov/7625653
https://pubmed.ncbi.nlm.nih.gov/7625653
Autor:
Nigel Clark, Nicola Meyers, Susan M. Kingsman, Stephen Matthews, Geoff Barton, Robert B. Russell, Nigel R. Burns, Helen Mills, Jonathan Boyd, Iain D. Campbell, Paul N. Barlow, Alan J. Kingsman, Mark Cunningham
Publikováno v:
Scopus-Elsevier
THE human immunodeficiency virus (HIV) matrix protein, p17, forms the outer shell of the core of the virus, lining the inner surface of the viral membrane1–4. The protein has several key functions. It orchestrates viral assembly via targeting signa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc456f6b0a9fbfeea6ecfd652ba95728
https://pubmed.ncbi.nlm.nih.gov/8065455
https://pubmed.ncbi.nlm.nih.gov/8065455
Publikováno v:
Molecular biotechnology. 1(2)
The self-assembly properties of a protein encoded by the TYA gene of the yeast Ty element can be exploited to produce hybrid Ty-VLPs (virus-like particles) (1,2). There has been developed a series of expression vectors that allow the construction of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fdb89d8194b9273ad575e07d749afee
https://pubmed.ncbi.nlm.nih.gov/7859157
https://pubmed.ncbi.nlm.nih.gov/7859157
Publikováno v:
International reviews of immunology. 11(2)
Vaccines need to activate antigen presenting cells, overcome genetic restriction in T-cell responses and elicit both T and B memory cells. In order to produce recombinant vaccines which can do this, considerable effort has been put into developing pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d62f11c9c14864a7979968e92be53c2b
https://pubmed.ncbi.nlm.nih.gov/8046274
https://pubmed.ncbi.nlm.nih.gov/8046274