Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Nigel P. Pringle"'
Publikováno v:
Journal of Visualized Experiments.
Detection of gene expression in different types of brain cells e.g., neurons, astrocytes, oligodendrocytes, oligodendrocyte precursors and microglia, can be hampered by the lack of specific primary or secondary antibodies for immunostaining. Here we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44cbf8ae45f7c17881675f27aa0ae338
https://doi.org/10.3791/53976
https://doi.org/10.3791/53976
Publikováno v:
Philosophical Transactions of the Royal Society B: Biological Sciences. 363:71-85
All the neurons and glial cells of the central nervous system are generated from the neuroepithelial cells in the walls of the embryonic neural tube, the ‘embryonic neural stem cells’. The stem cells seem to be equivalent to the so-called ‘radi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c88b2dd8ea2c496afce3a69ff8ecad3
https://doi.org/10.1098/rstb.2006.2013
https://doi.org/10.1098/rstb.2006.2013
Autor:
William D. Richardson, Nigel P. Pringle, David M. Ornitz, Marisa Howell, Jennifer S. Colvin, Wei-Ping Yu
Publikováno v:
Development. 130:93-102
The postnatal central nervous system (CNS) contains many scattered cells that express fibroblast growth factor receptor 3 transcripts (Fgfr3). They first appear in the ventricular zone (VZ) of the embryonic spinal cord in mid-gestation and then distr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dad537415917e40a2cc4221f751feafb
https://doi.org/10.1242/dev.00184
https://doi.org/10.1242/dev.00184
Autor:
William D. Richardson, Rachel H. Woodruff, Hazel K. Smith, Anita C. Hall, Nigel P. Pringle, Tao Sun
Publikováno v:
Glia. 29:136-142
One of the more surprising recent discoveries in glial biology has been that oligodendrocytes (OLs) originate from very restricted regions of the embryonic neural tube. This was surprising because myelinating OLs are widespread in the mature central
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fac9e4b2c7a70d5f06a1fdbd910d257b
https://doi.org/10.1002/(sici)1098-1136(20000115)29:2<136::aid-glia6>3.0.co
https://doi.org/10.1002/(sici)1098-1136(20000115)29:2<136::aid-glia6>3.0.co
Publikováno v:
Molecular and Cellular Neuroscience. 12:228-239
Neuroepithelial precursors in the ventral ventricular zone (VZ) of the spinal cord generate motor neurons (MNs) and interneurons, and then a subset of precursors starts to produce oligodendrocyte progenitors (OLPs). We show that OLPs originate in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f30ba2c29f5216af8b1ddadbc6a6a265
https://doi.org/10.1006/mcne.1998.0711
https://doi.org/10.1006/mcne.1998.0711
Publikováno v:
Neuron. 20(5):883-893
There is evidence that oligodendrocytes in the spinal cord are derived from a restricted part of the ventricular zone near the floor plate. An alternative view is that oligodendrocytes are generated from all parts of the ventricular zone. We reinvest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c657d834b923093c44c5cae99a96902f
Publikováno v:
Journal of Neuroscience Research. 47:264-270
A point mutation in exon 3 of the proteolipid protein (PLP) gene of the myelin-deficient (md) rat leads to a failure of oligodendrocyte maturation and early death of oligodendrocytes, resulting in dysmyelination. It has been suggested that an alterna
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ef7e788e22febac8e4cff25701bca911
https://doi.org/10.1002/(sici)1097-4547(19970201)47:3<264::aid-jnr4>3.0.co
https://doi.org/10.1002/(sici)1097-4547(19970201)47:3<264::aid-jnr4>3.0.co
Autor:
Henk Roelink, Wei-Ping Yu, Alan C. Peterson, Andrew Lumsden, Nigel P. Pringle, William D. Richardson, Sarah Guthrie
Publikováno v:
Developmental Biology. 177(1):30-42
Near the floor plate of the embryonic neural tube there is a group of neuroepithelial precursor cells that are specialized for production of the oligodendrocyte lineage. We performed experiments to test whether specification of these neuroepithelial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::087c68342c3e9b421397eda546a11877
Publikováno v:
Neuron. 12:1353-1362
2′,3′-cyclic-nucleotide 3′-phosphodiesterase (CNP) is an abundant protein of myelinating oligodendrocytes. We report that one of the alternatively spliced CNP mRNAs is also expressed in cultured oligodendrocyte progenitor cells. In situ hybridi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e44fa9feb6bded3c1f8037ff3acaafad
https://doi.org/10.1016/0896-6273(94)90450-2
https://doi.org/10.1016/0896-6273(94)90450-2
Autor:
Nigel P. Pringle, William D. Richardson, Matthew Grist, Tomoyuki Mitsumori, Kaylene M. Young, Nicoletta Kessaris
Publikováno v:
Glia. 58(8)
The lack of markers for astrocytes, particularly gray matter astrocytes, significantly hinders research into their development and physiological properties. We previously reported that fibroblast growth factor receptor 3 (Fgfr3) is expressed by radia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e403b8ef9bd81718186eb2ba0e05715
https://pubmed.ncbi.nlm.nih.gov/20155815
https://pubmed.ncbi.nlm.nih.gov/20155815