Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Nigel P. M. Sacks"'
Autor:
Nigel P. M. Sacks, Jo Marsden
Publikováno v:
American Journal of Cancer. 3:67-78
Hormone replacement therapy (HRT), whether this consists of unopposed estrogen or estrogen combined with a progestogen, is a very effective intervention for the management of estrogen deficiency symptoms. However, combined regimens are associated wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::45b3fcde4dc9dbb49193e28b9d4089ab
https://doi.org/10.2165/00024669-200403020-00001
https://doi.org/10.2165/00024669-200403020-00001
Autor:
Catherine L, Harper-Wynne, Nigel P M, Sacks, Karyn, Shenton, Fiona A, MacNeill, Paul, Sauven, Ian J, Laidlaw, Zen, Rayter, Stephanie, Miall, Angela, Howes, Janine, Salter, Margaret J, Hills, Frances M, Lowe, Roger, A'Hern, Nazar, Nasiri, Debbie, Doody, Jhangir, Iqbal, Mitchell, Dowsett
Publikováno v:
Journal of Clinical Oncology. 20:1026-1035
PURPOSE: To determine biologic differences, if any, between presurgical endocrine treatment with an aromatase inhibitor (vorozole) and tamoxifen in patients with postmenopausal primary breast cancer. PATIENTS AND METHODS: Randomization was to 12 week
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::795c9f86e15a288600a29041f2803888
https://doi.org/10.1200/jco.2002.20.4.1026
https://doi.org/10.1200/jco.2002.20.4.1026
Autor:
Nigel P. M. Sacks, Anthony R Hyett
Publikováno v:
British Menopause Society Journal. 7:16-19
The exact incidence of new breast symptoms with hormone replacement therapy (HRT) and its trophic effects on benign breast disorders is not well quantified and remains relatively understudied. This is a rapidly growing clinical issue as the rate of H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3038c22a3b7478d83fa04c0f80c2959d
https://doi.org/10.1258/136218001100321074
https://doi.org/10.1258/136218001100321074
Autor:
Nigel P. M. Sacks, Andrew J. Spillane
Publikováno v:
ANZ Journal of Surgery. 70:515-524
Background: Controversy continues to surround the best practice for management of the axilla in patients with early breast cancer (EBC), particularly the clinically negative axilla. The balance between therapeutic and staging roles of axillary surger
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c92fe783602175f419de79f348f5985
https://doi.org/10.1046/j.1440-1622.2000.01838.x
https://doi.org/10.1046/j.1440-1622.2000.01838.x
Publikováno v:
Trends in Endocrinology & Metabolism. 9:32-38
As breast cancer is known to be a tumour sensitive to the effects of endogenous oestrogens, clinicians are reluctant to prescribe hormone replacement therapy (HRT) to women with a history of previous breast cancer for fear of stimulating disease recu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49f8ed666104b3790fc44ff4e9fa65d5
https://doi.org/10.1016/s1043-2760(98)00003-4
https://doi.org/10.1016/s1043-2760(98)00003-4
Autor:
Nigel P. M. Sacks, Jo Marsden
Publikováno v:
The journal of the British Menopause Society. 8(4)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c62aeb25aa45fad01b9f70591f25514
https://pubmed.ncbi.nlm.nih.gov/12804318
https://pubmed.ncbi.nlm.nih.gov/12804318
Autor:
Nigel P. M. Sacks, Adrian L. Harris, Andrew P. Norman, Susan LeJeune, Kenneth G. C. Smith, Michael Greenall
Publikováno v:
European Journal of Cancer. 29:426-428
Cathepsin D and the epidermal growth factor receptor (EGFr) have both been proposed as poor prognostic markers in breast cancer. We have compared the tumour cytosolic cathepsin D level with EGFr and oestrogen receptor (ER) levels and the axillary nod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e057bc6e4139f4d0a2e9cf787852ae5
https://doi.org/10.1016/0959-8049(93)90401-z
https://doi.org/10.1016/0959-8049(93)90401-z
Publikováno v:
Genetic Predisposition to Cancer ISBN: 9780412565809
The search for genes which predispose to inherited breast cancer has intensified with the cloning of the BRCA1 and BRCA2 genes. This presents doctors with a new dilemma in the management of healthy women, at very high risk but with no clinical eviden
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aa61745128b3a51d60e8c104decd7f69
https://doi.org/10.1007/978-1-4899-4501-3_17
https://doi.org/10.1007/978-1-4899-4501-3_17
Publikováno v:
Journal of surgical oncology. 58(4)
We retrospectively reviewed the records of 317 needle-localization (NL) biopsies performed at the Royal Marsden Hospital during 1989-1992. The malignancy yield in our centre, where there is an emphasis on cooperation with an experienced radiologist a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfef819ec4c4c71112286755fbcea414
https://pubmed.ncbi.nlm.nih.gov/7723365
https://pubmed.ncbi.nlm.nih.gov/7723365
Autor:
Tamas Hickish, Hugo Ford, M. Nicolson, Janine Mansi, A Hill, V Nicolson, A. R. Norman, A. G. Nash, Nigel P. M. Sacks, M. Findlay, David Cunningham, R. Carter
Publikováno v:
Europe PubMed Central
Summary Purpose A phase II study was performed in patients with unresectable or metastatic gastric cancer evaluating the efficacy of a new chemotherapy schedule combining epirubicin and cisplatin with a continuous ambulatory infusion of 5-fluorouraci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9f78543e7454bd56a42444d8eece421
https://pubmed.ncbi.nlm.nih.gov/7993836
https://pubmed.ncbi.nlm.nih.gov/7993836