Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Nigel M, Davies"'
Autor:
Meenakshi Arora, Annette Bak, Nigel M. Davies, Ahil N. Ganesh, Sudhakar Garad, Eric Gruff, Tariq Islam, Mark J. Jackman, Swapnil Khadke, Fiona MacDougall, Sanyogitta Puri, M.N.V. Ravi Kumar, Jefferson D. Revell, Manuel V. Sanchez-Felix, J. Anand Subramony, Ruchit Trivedi, Puneet Tyagi, Dianxiong Zou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::984d7e77e384dfc40c26f3b082286337
https://doi.org/10.1016/b978-0-12-821061-1.00015-0
https://doi.org/10.1016/b978-0-12-821061-1.00015-0
Autor:
Staffan, Berg, Helena, Edlund, William, R F Goundry, Christel, A S Bergström, Nigel M, Davies
Publikováno v:
International Journal of Pharmaceutics. 628:122238
This paper reviews many of the properties of a peptide that need to be considered prior to development as an oral dosage form when co-formulated with a permeation enhancer to improve oral bioavailability, including the importance and implications of
Autor:
Nigel M. Davies, Lynette K. Lambert, P. Nicholas Shaw, Ross P. McGeary, Marguerite J. Kutyla, Benjamin P. Ross
Publikováno v:
International Journal of Pharmaceutics. 444:175-184
The aim of this work was to develop mucoadhesive hydrogels with variable drug delivery properties by crosslinking poly(acrylic acid) (PAA) with cyclodextrins (CDs). CD-PAA polymers with high CD content and good inter-batch reproducibility were synthe
Autor:
Ross P. McGeary, Jonathan Tuke, P. Nicholas Shaw, Nigel M. Davies, Michael W. Boehm, Benjamin P. Ross, Jason R. Stokes, Marguerite J. Kutyla
Publikováno v:
AAPS PharmSciTech. 14:301-311
The controlled release of diflunisal and fluconazole from tablets made of novel polymers, poly(acrylic acid) (PAA) crosslinked with either β-cyclodextrin (βCD) or hydroxypropyl-βCD (HPβCD), was investigated and Carbopol 934P (Carbopol) was used a
Publikováno v:
Journal of Liposome Research. 21:95-105
Targeted delivery of therapeutics to the endothelium is an important goal in the treatment of inflammatory diseases. The aim of this work was to exploit the overexpression of intercellular adhesion molecule-1 (ICAM-1) on activated endothelial cells f
Publikováno v:
International Journal of Pharmaceutics. 376:123-133
The aim of the study was to prepare cationic ISCOMs using cationic derivatives of the saponin Quil A. The polyamines ethylenediamine, spermidine and spermine were conjugated with the glucuronic acid moiety of Quil A. The aqueous solubility of the der
Publikováno v:
Drug Delivery. 16:82-91
The effects of chemical enhancers and sonophoresis on the transdermal permeation of tizanidine hydrochloride (TIZ) across mouse skin were investigated. Parameters including drug solubility, apparent partition coefficient (APC), drug permeation, and d
Autor:
Hsin-I Chang, Sherry Y. Wu, Mingtao Liang, Lisa N. Putral, Nigel M. Davies, Nigel A.J. McMillan
Publikováno v:
Pharmaceutical Research. 26:512-522
A simple yet novel method was developed to prepare stable PEGylated siRNA-loaded lipid particles which are suitable for in vivo use. PEGylated siRNA-loaded lipid particles were formulated by hydration of a freeze-dried matrix. The effect of various f
Publikováno v:
International Journal of Pharmaceutics. 362:141-146
Low molecular hydrophilic actives such as peptides are typically poorly encapsulated within poly(alkyl cyanoacrylate) nanoparticles when prepared from micellar or microemulsion templates. The aim of the present study was to investigate whether the en