Zobrazeno 1 - 10
of 115
pro vyhledávání: '"Nigel J. Fullwood"'
Autor:
Alina Akhbanbetova, Shinichiro Nakano, Stacy L. Littlechild, Robert D. Young, Madara Zvirgzdina, Nigel J. Fullwood, Ian Weston, Philip Weston, Shigeru Kinoshita, Naoki Okumura, Noriko Koizumi, Andrew J. Quantock
Publikováno v:
Journal of Ophthalmology, Vol 2017 (2017)
Purpose. To examine the effects of transcorneal freezing using a new cryoprobe designed for corneal endothelial surgery. Methods. A freezing console employing nitrous oxide as a cryogen was used to cool a series of different cryoprobe tip designs mad
Externí odkaz:
https://doaj.org/article/53de991711b74fd8917909f35f9e2f92
Autor:
Mark A. Pitt, Pierre L. Martin-Hirsch, Nigel J. Fullwood, Olaug Grude, Azzedine Hammiche, Hubert M. Pollock, Helen F. Stringfellow, Maneesh N. Singh, Michael J. Walsh, Francis L. Martin
Publikováno v:
Biomarker Insights, Vol 3, Pp 179-189 (2008)
Infrared (IR) absorbance of cellular biomolecules generates a vibrational spectrum, which can be exploited as a “biochemical fingerprint” of a particular cell type. Biomolecules absorb in the mid-IR (2–20 μm) and Fourier-transform infrared (FT
Externí odkaz:
https://doaj.org/article/d3853bf5f35147bbbf0666167462153e
Autor:
Michael J. Walsh, Maneesh N. Singh, Helen F. Stringfellow, Hubert M. Pollock, Azzedine Hammiche, Olaug Grude, Nigel J. Fullwood, Mark A. Pitt, Pierre L. Martin-Hirsch, Francis L. Martin
Publikováno v:
Biomarker Insights, Vol 3 (2008)
Infrared (IR) absorbance of cellular biomolecules generates a vibrational spectrum, which can be exploited as a “biochemical fingerprint” of a particular cell type. Biomolecules absorb in the mid-IR (2–20 μm) and Fourier-transform infrared (FT
Externí odkaz:
https://doaj.org/article/ad8a5a0465e641d4be322e654360e8fd
Autor:
Ruiz Ortega E, Townsend D, David Allsop, Masato Hasegawa, Airi Tarutani, Lucas H, Nigel J. Fullwood, Aggidis A, Amritpal Mudher, Shreyasi Chatterjee
There are currently no disease altering drugs available for Tauopathies such as Alzheimer’s disease, which alone is predicted to affect ~88 million people worldwide by 2050. As Tau aggregation underpins its toxicity, aggregation inhibitors are like
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14115746bbc1dba97c1e18a6a23ea9a4
https://eprints.soton.ac.uk/454449/
https://eprints.soton.ac.uk/454449/
Publikováno v:
Biochemistry
BIOCHEMISTRY
BIOCHEMISTRY
A pathological signature of Alzheimer's disease (AD) is the formation of neurofibrillary tangles comprising filamentous aggregates of the microtubule associated protein tau. Tau self-assembly is accelerated by polyanions including heparin, an analogu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d561d506724b8b8362ac264ccb3fad6
https://pubmed.ncbi.nlm.nih.gov/32954725
https://pubmed.ncbi.nlm.nih.gov/32954725
Autor:
Piyali Basak, Ying Yang, Nigel J. Fullwood, Samrat Paul, Sara J. Baldock, Soumik Podder, John G. Hardy, Chandan Kumar Ghosh, Bowen Xie
Materials capable of releasing reactive oxygen species (ROS) can display antibacterial and anticancer activity, and may also have anti-oxidant capacity if they suppress intracellular ROS (e.g. nitric oxide, NO) resulting in anti-inflammatory activity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2c93fb8fcc75a20079d38818d345b50
Autor:
Mohamed Saafi, Yin Chi, Bo Huang, Colin J. Lambert, Eric Whale, David Hepworth, Nigel J. Fullwood, Jianqiao Ye
Publikováno v:
Construction and Building Materials. 299:123867
Ordinary Portland cement (OPC) is the binding element in concrete materials and, CO2 emissions associated with its manufacturing and use is about 8% of the world's CO2 emissions. The engineering properties of hardened concrete depend on the amount of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dbcc285849009bfd69515cfdabfd08c3
https://doi.org/10.1016/j.conbuildmat.2021.123867
https://doi.org/10.1016/j.conbuildmat.2021.123867
Autor:
Maria Gregori, Mike Sherer, Vanessa Zambelli, Mark Taylor, Claire Louisa Tinker-Mill, Oleg Kolosov, Elisa Salvati, Claudia Balducci, Silvia Sesana, Gianluigi Forloni, David Allsop, Stephen Harris, Christos Michail, Francesca Re, Simona Mancini, Maria Michael, Nigel J. Fullwood, Massimo Masserini
Publikováno v:
Nanomedicine: Nanotechnology, Biology and Medicine. 13:723-732
Aggregation of amyloid-β peptide (Aβ) is a key event in the pathogenesis of Alzheimer's disease (AD). We investigated the effects of nanoliposomes decorated with the retro-inverso peptide RI-OR2-TAT (Ac-rGffvlkGrrrrqrrkkrGy-NH 2 ) on the aggregatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d6e5d2bd794a44f197629de4d60122c
https://doi.org/10.1016/j.nano.2016.10.006
https://doi.org/10.1016/j.nano.2016.10.006
Autor:
Pierre L. Martin-Hirsch, Shyam S. Matanhelia, Francis Martin, Alan J. Lawlor, Nigel J. Fullwood
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Scientific Reports
Scientific Reports
The structure and function of normal human prostate is still not fully understood. Herein, we concentrate on the different cell types present in normal prostate, describing some previously unreported types and provide evidence that prostasomes are pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::305073d64accfed2ed2c592d22c6cd70
https://doi.org/10.1038/s41598-019-40820-2
https://doi.org/10.1038/s41598-019-40820-2
Publikováno v:
International Journal of Nanomedicine
Alzheimer’s disease (AD) will affect around 115 million people worldwide by the year 2050. It is associated with the accumulation of misfolded and aggregated proteins (β-amyloid and tau) in the senile plaques and neurofibrillary tangles found in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e2e7e0872d535f5f34966608a643ab1
https://doi.org/10.2147/IJN.S183117
https://doi.org/10.2147/IJN.S183117