Zobrazeno 1 - 10
of 244
pro vyhledávání: '"Nigel J. Crowther"'
Autor:
Alana T. Brennan, Evelyn Lauren, Jacob Bor, Jaya A. George, Kamy Chetty, Koleka Mlisana, Andrew Dai, Siyabonga Khoza, Sydney Rosen, Andrew C. Stokes, Frederick Raal, Patricia Hibberd, Sara M. Alexanian, Matthew P. Fox, Nigel J. Crowther
Publikováno v:
BMC Health Services Research, Vol 23, Iss 1, Pp 1-13 (2023)
Abstract Background Research out of South Africa estimates the total unmet need for care for those with type 2 diabetes mellitus (diabetes) at 80%. We evaluated the care cascade using South Africa’s National Health Laboratory Service (NHLS) databas
Externí odkaz:
https://doaj.org/article/c9042d4348d94f6998caf5f237509605
Autor:
Surina Singh, Ananyo Choudhury, Scott Hazelhurst, Nigel J. Crowther, Palwendé R. Boua, Hermann Sorgho, Godfred Agongo, Engelbert A. Nonterah, Lisa K. Micklesfield, Shane A. Norris, Isaac Kisiangani, Shukri Mohamed, Francesc X. Gómez-Olivé, Stephen M. Tollman, Solomon Choma, J-T. Brandenburg, Michèle Ramsay
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Most hypertension-related genome-wide association studies (GWASs) focus on non-African populations, despite hypertension (a major risk factor for cardiovascular disease) being highly prevalent in Africa. The AWI-Gen study GWAS meta-analysis
Externí odkaz:
https://doaj.org/article/32f57f6a2f214833b2a4663b6da42781
Autor:
Erika Teresa Beidelman, Molly Rosenberg, Alisha N. Wade, Nigel J. Crowther, Corey A. Kalbaugh
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 1 (2024)
Background The burden of peripheral artery disease (PAD) is increasing in low‐ and middle‐income countries. Existing literature from sub‐Saharan Africa is limited and lacks population‐representative estimates. We estimated the burden and risk
Externí odkaz:
https://doaj.org/article/4fed2617b50745a49ff695b27b88a13c
Autor:
Ananyo Choudhury, Jean-Tristan Brandenburg, Tinashe Chikowore, Dhriti Sengupta, Palwende Romuald Boua, Nigel J. Crowther, Godfred Agongo, Gershim Asiki, F. Xavier Gómez-Olivé, Isaac Kisiangani, Eric Maimela, Matshane Masemola-Maphutha, Lisa K. Micklesfield, Engelbert A. Nonterah, Shane A. Norris, Hermann Sorgho, Halidou Tinto, Stephen Tollman, Sarah E. Graham, Cristen J. Willer, AWI-Gen study, H3Africa Consortium, Scott Hazelhurst, Michèle Ramsay
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Genetic associations and polygenic scores for lipid traits have low transferability to African individuals. Here, the authors perform a large sub-Sarahan African lipid GWAS and find that larger datasets and better global representation in discovery G
Externí odkaz:
https://doaj.org/article/20c18ebde24c413f978062a3e9374696
Autor:
Palwende Romuald Boua, Jean-Tristan Brandenburg, Ananyo Choudhury, Hermann Sorgho, Engelbert A. Nonterah, Godfred Agongo, Gershim Asiki, Lisa Micklesfield, Solomon Choma, Francesc Xavier Gómez-Olivé, Scott Hazelhurst, Halidou Tinto, Nigel J. Crowther, Christopher G. Mathew, Michèle Ramsay, AWI-Gen Study, the H3Africa Consortium
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
Genetic studies of disease-relevant traits have mostly been performed on European populations. Here, the authors perform a genome-wide association study for carotid intima-media thickness, in sub-Saharan African samples, finding population-specific a
Externí odkaz:
https://doaj.org/article/a429f330eef7484d88ede78d14dca025
Autor:
Engelbert A. Nonterah, Nigel J. Crowther, Kerstin Klipstein‐Grobusch, Abraham R. Oduro, Maryam Kavousi, Godfred Agongo, Todd J. Anderson, Gershim Asiki, Palwendé R. Boua, Solomon S. R. Choma, David J. Couper, Gunnar Engström, Jacqueline de Graaf, Jussi Kauhanen, Eva M. Lonn, Ellisiv B. Mathiesen, Lisa K. Micklesfield, Shuhei Okazaki, Joseph F. Polak, Tatjana Rundek, Jukka T. Salonen, Stephen M. Tollman, Tomi‐Pekka Tuomainen, Diederick E. Grobbee, Michéle Ramsay, Michiel L. Bots
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 11, Iss 15 (2022)
Background The major risk factors for atherosclerotic cardiovascular disease differ by race or ethnicity but have largely been defined using populations of European ancestry. Despite the rising prevalence of cardiovascular disease in Africa there are
Externí odkaz:
https://doaj.org/article/bcabad2309a54ee5aca93bb07626aa4f
Autor:
Sofia Ramos, Sheetal Daya, Nigel J. Crowther, Lushen Pillay, Mohammed Tikly, Nasrin Goolam Mahyoodeen
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
BackgroundPsoriasis is associated with a high prevalence of cardiovascular disease in Caucasians, but only a few studies from sub-Saharan Africa have investigated the prevalence of cardiovascular disease in patients with psoriasis. Abdominal aortic c
Externí odkaz:
https://doaj.org/article/8074d6b9c2274bdd8a12daabc52912ed
Autor:
Engelbert A. Nonterah, Nigel J. Crowther, Abraham Oduro, Godfred Agongo, Lisa K. Micklesfield, Palwendé R. Boua, Solomon S. R. Choma, Shukri F. Mohamed, Herman Sorgho, Stephen M. Tollman, Shane A. Norris, Frederick J. Raal, Diederick E. Grobbee, Michelé Ramsay, Michiel L. Bots, Kerstin Klipstein-Grobusch, as part of the H3Africa AWI-Gen study
Publikováno v:
BMC Medicine, Vol 19, Iss 1, Pp 1-12 (2021)
Abstract Background The cardiovascular health index (CVHI) introduced by the American Heart Association is a valid, accessible, simple, and translatable metric for monitoring cardiovascular health in a population. Components of the CVHI include the f
Externí odkaz:
https://doaj.org/article/e7c9355aa83b4a46bf0f38a76d8eb1a7
Publikováno v:
Kidney & Blood Pressure Research, Vol 45, Iss 6, Pp 1009-1017 (2020)
Introduction: The C allele of the ectonucleotide pyrophosphatase/phosphodiesterase 1 (ENPP-1) rs1044498 polymorphism has previously been associated with increased binding of ENPP-1 to the insulin receptor (IR), resulting in decreased IR signalling an
Externí odkaz:
https://doaj.org/article/9e588583f9bd4674897f1c25c8852cda
Autor:
Godfred Agongo, Frederick Raal, Engelbert A. Nonterah, Cornelius Debpuur, Abraham R. Oduro, Michèle Ramsay, Nigel J. Crowther
Publikováno v:
PLoS ONE, Vol 17, Iss 12 (2022)
Few studies have compared the utility of serum levels of lipid fractions in cardiovascular disease (CVD) risk assessment in sub-Saharan Africa (SSA). The current study interrogated this question among men and women aged 40–60 years in rural norther
Externí odkaz:
https://doaj.org/article/d48fd40367e041b9a9e69a145b7119f8