Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Nigel J Klein"'
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e27030 (2011)
BackgroundEnteropathogenic (EPEC) and Enteroaggregative (EAEC) E. coli have similar, but distinct clinical symptoms and modes of pathogenesis. Nevertheless when they infect the gastrointestinal tract, it is thought that their flagellin causes IL-8 re
Externí odkaz:
https://doaj.org/article/7cb448ced2804feb83ff843adec5927f
Autor:
Lily Gates, Talisa Mistry, Olumide Ogunbiyi, Kerry-Anne Kite, Nigel J. Klein, Neil J. Sebire, Dagmar G. Alber
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
BackgroundSudden unexpected death in infancy (SUDI) is the most common cause of post-neonatal death in the developed world. Following an extensive investigation, the cause of ~40% of deaths remains unknown. It is hypothesized that a proportion of dea
Externí odkaz:
https://doaj.org/article/80de08c9f2b3497fae742f798bdd30f2
Publikováno v:
Cerebrovascular Diseases Extra, Vol 5, Iss 2, Pp 68-74 (2015)
Background: We have previously shown that recurrent arterial ischaemic stroke (AIS) in children with cerebral arteriopathy is associated with increased circulating endothelial cells and endothelial microparticles, consistent with ongoing endothelial
Externí odkaz:
https://doaj.org/article/c90c803670cf4a1a9a3cf3b928c4f8a1
Publikováno v:
Arthritis Research & Therapy
Introduction Previously, we demonstrated that children with active systemic vasculitis (SV) have higher circulating CD34 + CD133 + KDR+ endothelial progenitor cells (EPC); the function of these EPCs, and their relationship with disease activity in va
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c4e23a31ab3c165d9cfec380428b120c
https://pubmed.ncbi.nlm.nih.gov/26475131
https://pubmed.ncbi.nlm.nih.gov/26475131
Autor:
Dominic L. Jack, Alister W. Dodds, Natasha Anwar, Catherine A. Ison, Alex Law, Matthias Frosch, Malcolm W. Turner, Nigel J. Klein
Publikováno v:
The Journal of Immunology. 160:1346-1353
Mannose-binding lectin (MBL) is a serum protein that has been demonstrated to activate the classical complement pathway and to function directly as an opsonin. Although MBL deficiency is associated with a common opsonic defect and a predisposition to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e13bb929699a67737f59eec0cf7984f4
https://doi.org/10.4049/jimmunol.160.3.1346
https://doi.org/10.4049/jimmunol.160.3.1346
Autor:
Despina, Eleftheriou, Tim, Cox, Dawn, Saunders, Nigel J, Klein, Paul A, Brogan, Vijeya, Ganesan
Publikováno v:
Developmental medicine and child neurology. 52(9)
We compared the clinical utility of magnetic resonance angiography (MRA) to catheter cerebral angiography (CA) in the investigation of children with suspected central nervous system (CNS) vasculitis.Single-centre retrospective review of children with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::155221195d7c34315e34c493299fa3e6
https://pubmed.ncbi.nlm.nih.gov/20187886
https://pubmed.ncbi.nlm.nih.gov/20187886
Autor:
Parjeet K, Boughan, Richard H, Argent, Mathilde, Body-Malapel, Jong-Hwan, Park, Katie E, Ewings, Andrew G, Bowie, Shao Jin, Ong, Simon J, Cook, Ole E, Sorensen, Barbara A, Manzo, Naohiro, Inohara, Nigel J, Klein, Gabriel, Nuñez, John C, Atherton, Mona, Bajaj-Elliott
Publikováno v:
The Journal of biological chemistry. 281(17)
Host-pathogen interactions that allow Helicobacter pylori to survive and persist in the stomach of susceptible individuals remain unclear. Human beta-defensins (hBDs), epithelial-derived antimicrobial peptides are critical components of host-defense
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9d85623f9aee4c32312387aaf00342b0
https://pubmed.ncbi.nlm.nih.gov/16513653
https://pubmed.ncbi.nlm.nih.gov/16513653
Autor:
Helen Payne, Man K. Chan, Sarah A. Watters, Kennedy Otwombe, Nei-Yuan Hsiao, Abdel Babiker, Avy Violari, Mark F. Cotton, Diana M. Gibb, Nigel J. Klein
Publikováno v:
AIDS Research and Therapy, Vol 18, Iss 1, Pp 1-12 (2021)
Abstract Background Reduction of the reservoir of latent HIV-infected cells might increase the possibility of long-term remission in individuals living with HIV. We investigated factors associated with HIV-1 proviral DNA levels in children receiving
Externí odkaz:
https://doaj.org/article/9bedca26bec5403c8510741eb07e3ca4
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
Sudden unexpected death in infancy (SUDI) is the sudden and unexpected death of an apparently healthy infant occurring within the first year of life where the cause is not immediately obvious. It is believed that a proportion of unexplained infant de
Externí odkaz:
https://doaj.org/article/5ff42b90ba6344289bb3877a4313047a