Zobrazeno 1 - 10
of 347
pro vyhledávání: '"Nigel J, Bundred"'
Autor:
Nigel J. Bundred, Emma Barrett, Chriss Todd, Julie Morris, Donna Watterson, Arnie Purushotham, Katie Riches, Abigail Evans, Anthony Skene, Vaughan Keeley, the Investigators of BEA/PLACE studies
Publikováno v:
Cancer Medicine, Vol 12, Iss 5, Pp 5506-5516 (2023)
Abstract Around 25% of women undergoing Axillary Clearance (ANC) develop lymphedema (LE). Intervention with a compression garment is recommended to prevent LE but no randomised evidence exists to support this strategy. Methods A randomised trial test
Externí odkaz:
https://doaj.org/article/7da228a3a57248068b9d6f65d33d72e8
Autor:
Simon Timbrell, Hosam Aglan, Angela Cramer, Phil Foden, David Weaver, Jonathan Pachter, Aoife Kilgallon, Robert B. Clarke, Gillian Farnie, Nigel J. Bundred
Publikováno v:
npj Breast Cancer, Vol 7, Iss 1, Pp 1-13 (2021)
Abstract Cancer stem-like cells (CSC) contribute to therapy resistance and recurrence. Focal adhesion kinase (FAK) has a role in CSC regulation. We determined the effect of FAK inhibition on breast CSC activity alone and in combination with adjuvant
Externí odkaz:
https://doaj.org/article/0042b7fcefc749e8a9c051f9adcd6bb2
Autor:
John Castle, Emma Blower, Nigel J. Bundred, James R. Harvey, Jecko Thachil, Andrea Marshall, Karina Cox, Silvia Cicconi, Chris Holcombe, Carlos Palmieri, Cliona C. Kirwan
Publikováno v:
Trials, Vol 21, Iss 1, Pp 1-11 (2020)
Abstract Background Breast cancer patients are at a four-fold increased risk of developing a venous thromboembolism (VTE), a major cause of death in this group. Conversely, coagulation factors promote tumour growth and metastasis. This has been evide
Externí odkaz:
https://doaj.org/article/6034727a1a5a448ea4b2a84673e1349f
Autor:
Hudhaifah Shaker, Nigel J. Bundred, Göran Landberg, Susan A. Pritchard, Harith Albadry, Sarah L. Nicholson, Lauren J. Harries, Jing Y. E. Heah, John Castle, Cliona C. Kirwan
Publikováno v:
Cancer Medicine, Vol 9, Iss 5, Pp 1768-1778 (2020)
Abstract Background Tumor stroma, of which fibroblasts are the most abundant cell, resembles a non‐healing wound, where a procoagulant environment creates a permissive milieu for cancer growth. We aimed to determine if tumor expression of coagulati
Externí odkaz:
https://doaj.org/article/f8cbc09ec78246c7b08d0b699a5cd27f
Autor:
James R Bundred, David Dodwell, Ramsay Cuttress, Sarah Michael, Beth Stuart, Bernd Holleczek, Kerri Beckmann, Jane Dahlstrom, Nigel J Bundred
Publikováno v:
Cancer Research. 82:P3-18
Background: International guidelines state that any post-surgical tumour margin wider than tumour on ink following breast conserving surgery (BCS) for early invasive breast cancer is acceptable, based on analyses of margin width and local recurrence(
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::588de66bbac059dee39406f769a43595
https://doi.org/10.1158/1538-7445.sabcs21-p3-18-07
https://doi.org/10.1158/1538-7445.sabcs21-p3-18-07
Autor:
Jack Cuzick, Ian S. Fentiman, Nigel J. Bundred, Sarah E. Pinder, J. Louise Jones, Pauline M. Levey, Mangesh A. Thorat
Supplementary Figure 1 summarizes the treatment allocation in the UK/ANZ DCIS trial, and distribution of patients in the biomarker study subset (BSS1).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::006cadf6105978126661f1efb86f2b86
https://doi.org/10.1158/1078-0432.22479015.v1
https://doi.org/10.1158/1078-0432.22479015.v1
Autor:
Robert B. Clarke, Sacha J. Howell, Göran Landberg, Amrita Shergill, Bruno M Simões, Nigel J. Bundred, Gillian Farnie, Jagdeep K. Singh
Purpose: Breast cancer stem-like cells (CSC) are an important therapeutic target as they are predicted to be responsible for tumor initiation, maintenance, and metastases. Interleukin (IL)-8 is upregulated in breast cancer and is associated with poor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::579f63499469f0946abe81addce01d95
https://doi.org/10.1158/1078-0432.c.6522329
https://doi.org/10.1158/1078-0432.c.6522329
Autor:
Robert B. Clarke, Sacha J. Howell, Göran Landberg, Amrita Shergill, Bruno M Simões, Nigel J. Bundred, Gillian Farnie, Jagdeep K. Singh
PDF file - 79K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81a0e5d9eca8e7e9c964397fd274d5e4
https://doi.org/10.1158/1078-0432.22451906
https://doi.org/10.1158/1078-0432.22451906
Autor:
Jack Cuzick, Ian S. Fentiman, Nigel J. Bundred, Sarah E. Pinder, J. Louise Jones, Pauline M. Levey, Mangesh A. Thorat
Purpose:The prognostic value of estrogen receptor (ER)/progesterone receptor (PgR) expression in ductal carcinoma in situ (DCIS) is unclear. We observed multi-clonality when evaluating ER/PgR expression in the UK/ANZ DCIS trial, therefore, we investi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac1d5b091326d47dd99c9e9922bc1e8d
https://doi.org/10.1158/1078-0432.c.6530106.v1
https://doi.org/10.1158/1078-0432.c.6530106.v1
Autor:
Robert B. Clarke, Sacha J. Howell, Göran Landberg, Amrita Shergill, Bruno M Simões, Nigel J. Bundred, Gillian Farnie, Jagdeep K. Singh
PDF file - 66K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2999241b5e3b872e69fa9c9b2e8b1ca4
https://doi.org/10.1158/1078-0432.22451903.v1
https://doi.org/10.1158/1078-0432.22451903.v1