Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Nigel D. Christie"'
Antineoplastic Agents 293. The Exceptional Human Cancer Cell Growth Inhibitors Spongistatins 6 and 7
Autor:
George R. Pettit, Jean M. Schmidt, Michael R. Boyd, Nigel D. Christie, Zbigniew A. Cichacz, Cherry L. Herald, Feng Gao
Publikováno v:
Natural Product Letters. 3:239-244
A twenty year investigation of the South African marine sponge Spirastrella spinispirulifera (Carter, 1879) for antineoplastic constituents has now led to discovery of spongistatin 6 (1e) and 7 (2b) in 3.5 × 10−7% and 2.2 × 10−7% yields. Struct
Autor:
Dennis L. Doubek, Jean M. Schmidt, Cherry L. Herald, Claude Dufresne, Michael R. Boyd, Masuo Inoue, Nigel D. Christie, George R. Pettit, Yoshiaki Kamano
Publikováno v:
The Journal of Organic Chemistry. 57:429-431
Autor:
Nigel D. Christie, Michael D. Williams, Jun-Ping Xu, Jean M. Schmidt, George R. Pettit, Michael R. Boyd, Dennis L. Doubek
Publikováno v:
Journal of natural products. 57(1)
Further investigation of antineoplastic constituents from the marine worm Cephalodiscus gilchristi, employing a 450 kg re-collection from the Indian Ocean (Southeast Africa), has led to isolation and structural determination of two previously undetec
Autor:
Fred E. Boettner, Zbigniew A. Cichacz, Nigel D. Christie, Michael R. Boyd, George R. Pettit, Cherry L. Herald, Feng Gao, Jean M. Schmidt
Publikováno v:
Journal of the Chemical Society, Chemical Communications. :1805
The Southwest Indian Ocean marine sponge Spirastrella spinispirulifera has been found to contain (in 10–7% yields) two extraordinarily potent (Gl50ca. 10–8µg ml–1) human cancer cell line inhibitors designated spongistatins 4 1d and 5 2.
Autor:
Jean M. Schmidt, Nigel D. Christie, Dennis L. Doubek, George R. Pettit, Masuo Inoue, Claude Dufresne, Yoshiaki Kamano
Publikováno v:
Canadian Journal of Chemistry. 67:1509-1513
The Indian Ocean (South African) marine worm Cephalodiscusgilchristi (Hemichordata phylum) has been found to contain a series of unusual disteroidal alkaloids, designated the cephalostatins, that possess exceptionally potent lymphocytic leukemia (mur
Autor:
Jean M. Schmidt, Masuo Inoue, Yoshiaki Kamano, Nigel D. Christie, Delbert L. Herald, Christoph A. Arm, Timothy S. Krupa, George R. Pettit, Dennis L. Doubek, Claude Dufresne
Publikováno v:
Journal of the American Chemical Society. 110:2006-2007
Autor:
Nigel D. Christie, Margaret L. Niven, Yoshiaki Kamano, Delbert L. Herald, Claude Dufresne, George R. Pettit, Masuo Inoue
Publikováno v:
Journal of the Chemical Society, Chemical Communications. :865
Three new cephalostatins possessing powerful cytostatic activity have been isolated from the Indian Ocean marine worm Cephalodiscus gilchristi; structures were assigned on the basis of detailed high-field n.m.r. and mass spectral analyses.
Autor:
Yoshiaki Kamano, Claude Dufresne, Nigel D. Christie, Masuo Inoue, Delbert L. Herald, George R. Pettit, Margaret L. Niven
Publikováno v:
Journal of the Chemical Society, Chemical Communications. :1440
Autor:
Pettit, George R., Herald, Cherry L., Cichacz, Zbigniew A., Gao, Feng, Boyd, Michael R., Christie, Nigel D., Schmidt, Jean M.
Publikováno v:
Natural Product Letters; Dec1993, Vol. 3 Issue 4, p239-244, 6p
Publikováno v:
Journal of the Chemical Society, Chemical Communications; 12/21/1993, Issue 24, pP093-P096, 4p