Zobrazeno 1 - 10
of 81
pro vyhledávání: '"Nigel Brooks"'
Publikováno v:
Heliyon, Vol 10, Iss 9, Pp e30178- (2024)
Developing multifunctional nanomaterials through environmentally friendly and efficient approaches is a pivotal focus in nanotechnology. This study aimed to employ a biogenic method to synthesize multifunctional copper oxide nanoparticles (LI-CuO NPs
Externí odkaz:
https://doaj.org/article/e29d5fd1284844d5b64d9a102fcb4e70
Autor:
Addisie Geremew, John Gonzalles, Elisha Peace, Selamawit Woldesenbet, Sheena Reeves, Nigel Brooks, Laura Carson
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 2, p 904 (2024)
In the face of evolving healthcare challenges, the utilization of silver nanoparticles (AgNPs) has emerged as a compelling solution due to their unique properties and versatile applications. The aim of this study was the synthesis and characterizatio
Externí odkaz:
https://doaj.org/article/8c640eccdf1a49a39d7a3f8034c4fd76
Autor:
Addisie Geremew, Laura Carson, Selamawit Woldesenbet, Huichen Wang, Sheena Reeves, Nigel Brooks, Premkumar Saganti, Aruna Weerasooriya, Elisha Peace
Publikováno v:
Frontiers in Plant Science, Vol 14 (2023)
BackgroundThe sustainability of crop production is impacted by climate change and land degradation, and the advanced application of nanotechnology is of paramount importance to overcome this challenge. The development of nanomaterials based on essent
Externí odkaz:
https://doaj.org/article/6d2f99b40b314354bc99197b138bed39
Autor:
Jeannine Diesch, Marguerite-Marie Le Pannérer, René Winkler, Raquel Casquero, Matthias Muhar, Mark van der Garde, Michael Maher, Carolina Martínez Herráez, Joan J. Bech-Serra, Michaela Fellner, Philipp Rathert, Nigel Brooks, Lurdes Zamora, Antonio Gentilella, Carolina de la Torre, Johannes Zuber, Katharina S. Götze, Marcus Buschbeck
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Azacitidine (AZA) treatment is used for patients with myelodysplasias that cannot undergo bone marrow transplantation; however, AZA treatment is only partially effective. Here the authors show synergy of AZA with compounds inhibiting the chromatin re
Externí odkaz:
https://doaj.org/article/d0619bde27374a0bbc9ce933934d9f91
Autor:
A. Nigel Brooks, Stephen R. Wedge, Susan E. Critchlow, Craig N. Robson, Simon T. Barry, Chris Womack, Luke Gaughan, Alfred Rabow, Robert H. Bradbury, Rhys D.O. Jones, Joanne Wilson, Marie Cumberbatch, Vivien N. Jacobs, Fadhel S. Shaheen, Elizabeth Mouchet, Dawn Trueman, Natalie C. Stratton, Nicola Broadbent, Sandra R. Brave, Tom P.J. Dunkley, Graeme E. Walker, David M. Robinson, Andrew G. Thomason, Sarah J. Ross, Sarah A. Loddick
PDF - 56KB, Supplementary methods detailing Relative peptide quantification by selected reaction monitoring (SRM)using mass spectrometry
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54d12f691841ae5003bde43d483fc498
https://doi.org/10.1158/1535-7163.22500958
https://doi.org/10.1158/1535-7163.22500958
Autor:
A. Nigel Brooks, Stephen R. Wedge, Susan E. Critchlow, Craig N. Robson, Simon T. Barry, Chris Womack, Luke Gaughan, Alfred Rabow, Robert H. Bradbury, Rhys D.O. Jones, Joanne Wilson, Marie Cumberbatch, Vivien N. Jacobs, Fadhel S. Shaheen, Elizabeth Mouchet, Dawn Trueman, Natalie C. Stratton, Nicola Broadbent, Sandra R. Brave, Tom P.J. Dunkley, Graeme E. Walker, David M. Robinson, Andrew G. Thomason, Sarah J. Ross, Sarah A. Loddick
PDF - 464KB, Supplementary Figure 1: Inhibition of AR transcripts with AZD3514 treated LNCaPs in steroid free media and the timecourse of AZD3514 effects in the presence and absence of DHT. Supplementary Figure 2: Effect of AZD3514 on growth of AR ne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5d194c3a51c866f292b69afd928b73e
https://doi.org/10.1158/1535-7163.22500961
https://doi.org/10.1158/1535-7163.22500961
Autor:
A. Nigel Brooks, Stephen R. Wedge, Susan E. Critchlow, Craig N. Robson, Simon T. Barry, Chris Womack, Luke Gaughan, Alfred Rabow, Robert H. Bradbury, Rhys D.O. Jones, Joanne Wilson, Marie Cumberbatch, Vivien N. Jacobs, Fadhel S. Shaheen, Elizabeth Mouchet, Dawn Trueman, Natalie C. Stratton, Nicola Broadbent, Sandra R. Brave, Tom P.J. Dunkley, Graeme E. Walker, David M. Robinson, Andrew G. Thomason, Sarah J. Ross, Sarah A. Loddick
PDF - 71KB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36cd40a1e742de8a4011274fdf37bb1e
https://doi.org/10.1158/1535-7163.22500964.v1
https://doi.org/10.1158/1535-7163.22500964.v1
Autor:
Johann S. de Bono, Neil Pegg, Karen E. Knudsen, Matthew J. Schiewer, David Taddei, Amanda Swain, Jian Ning, Antje J. Neeb, Suzanne Carreira, Nina Tunariu, Rita Pereira, Ana Ferreira, Mateus Crespo, Susana Miranda, Veronica S. Gil, Gareth W. Harbottle, Don Smyth, Richard Brown, Silvia Paoletta, Jonathan Shannon, Stuart Onions, Jenny Worthington, Stuart Thomson, Jordan Lane, Amy Prosser, Meera Raja, Barbara Young, William West, Denisa Bogdan, Jan Rekowski, Bora Gurel, Ruth Riisnaes, Ines Figueiredo, Abhijit Pal, Saswati N. Chand, Christopher McNair, Wei Yuan, Nigel Brooks, Adam Sharp, Jonathan Welti
Resistance to androgen receptor (AR) blockade in castration-resistant prostate cancer (CRPC) is associated with sustained AR signaling, including through alternative splicing of AR (AR-SV). Inhibitors of transcriptional coactivators that regulate AR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c73d8a93c6f4a3feb2612ceef314ced
https://doi.org/10.1158/2159-8290.c.6549379
https://doi.org/10.1158/2159-8290.c.6549379
Autor:
A. Nigel Brooks, Stephen R. Wedge, Susan E. Critchlow, Craig N. Robson, Simon T. Barry, Chris Womack, Luke Gaughan, Alfred Rabow, Robert H. Bradbury, Rhys D.O. Jones, Joanne Wilson, Marie Cumberbatch, Vivien N. Jacobs, Fadhel S. Shaheen, Elizabeth Mouchet, Dawn Trueman, Natalie C. Stratton, Nicola Broadbent, Sandra R. Brave, Tom P.J. Dunkley, Graeme E. Walker, David M. Robinson, Andrew G. Thomason, Sarah J. Ross, Sarah A. Loddick
PDF - 329KB, Supplementary Table 1: TSQ Vantage mass spectrometry instrument settings. Supplementary Table 2: 4000 QTRAP mass spectrometry instrument settings. Supplementary Table 3: The half-life of AR for the first 6 hours following treatment calcu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b48ad0925bc03fcf57e4609a27abf58
https://doi.org/10.1158/1535-7163.22500955
https://doi.org/10.1158/1535-7163.22500955
Autor:
Johann S. de Bono, Neil Pegg, Karen E. Knudsen, Matthew J. Schiewer, David Taddei, Amanda Swain, Jian Ning, Antje J. Neeb, Suzanne Carreira, Nina Tunariu, Rita Pereira, Ana Ferreira, Mateus Crespo, Susana Miranda, Veronica S. Gil, Gareth W. Harbottle, Don Smyth, Richard Brown, Silvia Paoletta, Jonathan Shannon, Stuart Onions, Jenny Worthington, Stuart Thomson, Jordan Lane, Amy Prosser, Meera Raja, Barbara Young, William West, Denisa Bogdan, Jan Rekowski, Bora Gurel, Ruth Riisnaes, Ines Figueiredo, Abhijit Pal, Saswati N. Chand, Christopher McNair, Wei Yuan, Nigel Brooks, Adam Sharp, Jonathan Welti
Supplementary figures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d313da933b889d09a6fcaf5a2385ff7
https://doi.org/10.1158/2159-8290.22540441.v1
https://doi.org/10.1158/2159-8290.22540441.v1