Zobrazeno 1 - 10
of 198
pro vyhledávání: '"Nigel B Jamieson"'
Autor:
Bryan W Miller, Jennifer P Morton, Mark Pinese, Grazia Saturno, Nigel B Jamieson, Ewan McGhee, Paul Timpson, Joshua Leach, Lynn McGarry, Emma Shanks, Peter Bailey, David Chang, Karin Oien, Saadia Karim, Amy Au, Colin Steele, Christopher Ross Carter, Colin McKay, Kurt Anderson, Thomas R Jeffry Evans, Richard Marais, Caroline Springer, Andrew Biankin, Janine T Erler, Owen J Sansom
Publikováno v:
EMBO Molecular Medicine, Vol 7, Iss 8, Pp 1063-1076 (2015)
Abstract Pancreatic ductal adenocarcinoma (PDAC) is one of the leading causes of cancer‐related mortality. Despite significant advances made in the treatment of other cancers, current chemotherapies offer little survival benefit in this disease. Pa
Externí odkaz:
https://doaj.org/article/34d487ab4e35409d91ce088f409d4cf7
Autor:
Liane M McGlynn, Simon McCluney, Nigel B Jamieson, Jackie Thomson, Alasdair I MacDonald, Karin Oien, Euan J Dickson, C Ross Carter, Colin J McKay, Paul G Shiels
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0131344 (2015)
The sirtuin gene family has been linked with tumourigenesis, in both a tumour promoter and suppressor capacity. Information regarding the function of sirtuins in pancreatic cancer is sparse and equivocal. We undertook a novel study investigating SIRT
Externí odkaz:
https://doaj.org/article/8273598e05554560a83e1781d238c0ff
Autor:
Josh McGovern, Stephen Leadbitter, Gillian Miller, Adam Hounat, Irvine Kamande, Ross D. Dolan, Paul G. Horgan, David K. Chang, Nigel B. Jamieson, Donald C. McMillan
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-8 (2023)
Abstract High vagal nerve activity, reliability measured by HRV, is considered protective in cancer, reducing oxidative stress, inflammation and opposing sympathetic nerve activity. The present monocentric study examines the relationship between HRV,
Externí odkaz:
https://doaj.org/article/0344f688208c4bb4922fe908ca3e567e
Autor:
Colin S. Wood, Kathryn A.F. Pennel, Holly Leslie, Assya Legrini, Andrew J. Cameron, Lydia Melissourgou-Syka, Jean A. Quinn, Hester C. van Wyk, Jennifer Hay, Antonia K. Roseweir, Colin Nixon, Campbell S.D. Roxburgh, Donald C. McMillan, Andrew V. Biankin, Owen J. Sansom, Paul G. Horgan, Joanne Edwards, Colin W. Steele, Nigel B. Jamieson
Publikováno v:
Cancer Research. 83:1329-1344
Strong immune responses in primary colorectal cancer correspond with better patient survival following surgery compared with tumors with predominantly stromal microenvironments. However, biomarkers to identify patients with colorectal cancer liver me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::774945f4abcfa2bf86be777d51c0e348
https://doi.org/10.1158/0008-5472.can-22-2794
https://doi.org/10.1158/0008-5472.can-22-2794
Autor:
David K. Chang, Roberto Salvia, Rosie Upstill-Goddard, Federica Marchesi, Alessandro Zerbi, Nigel B. Jamieson, Rita T. Lawlor, Stephan Dreyer, Anthony J. Gill, Jaswinder S. Samra, Euan J. Dickson, Andrew V. Biankin, Anubhav Mittal, Amber L. Johns, Aldo Scarpa, Georgios Gemenetzis, Kirsty Bisset, Fraser Duthie, Antonio Pea, Sarah Rae, Colin J. McKay, Alessandra Pulvirenti
Publikováno v:
Annals of Surgery. 277:e396-e405
Background: The long-term outcomes following surgical resection for pancreatic ductal adenocarcinoma (PDAC) remains poor, with only 20% of patients surviving 5 years after pancreatectomy. Patient selection for surgery remains sub-optimal largely due
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55c1bdc0c3442237b17767719efbaf56
https://doi.org/10.1097/sla.0000000000005050
https://doi.org/10.1097/sla.0000000000005050
Publikováno v:
Frontiers in Medicine, Vol 7 (2020)
Well-differentiated pancreatic neuroendocrine tumors are increasingly diagnosed neoplasms. For localized disease, surgery is the first-line therapy and is curative in most cases. However, although recurrence is a rare event, it can still occur up to
Externí odkaz:
https://doaj.org/article/78f4093fee6c4e00a603deca7f84720c
Autor:
Nigel B. Jamieson, Colin W. Steele, Joanne Edwards, Paul G. Horgan, Owen J. Sansom, Andrew V. Biankin, Donald C. McMillan, Campbell S.D. Roxburgh, Colin Nixon, Antonia K. Roseweir, Jennifer Hay, Hester C. van Wyk, Jean A. Quinn, Lydia Melissourgou-Syka, Andrew J. Cameron, Assya Legrini, Holly Leslie, Kathryn A.F. Pennel, Colin S. Wood
All supplementary figures and supplementary tables 1 and 2 from the manuscript
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::403e64c8ec0da6f59bb48f6e55065ecc
https://doi.org/10.1158/0008-5472.22633296.v1
https://doi.org/10.1158/0008-5472.22633296.v1
Autor:
Nigel B. Jamieson, Colin W. Steele, Joanne Edwards, Paul G. Horgan, Owen J. Sansom, Andrew V. Biankin, Donald C. McMillan, Campbell S.D. Roxburgh, Colin Nixon, Antonia K. Roseweir, Jennifer Hay, Hester C. van Wyk, Jean A. Quinn, Lydia Melissourgou-Syka, Andrew J. Cameron, Assya Legrini, Holly Leslie, Kathryn A.F. Pennel, Colin S. Wood
Gene Set Enrichment Analysis results obtained by interrogating ranked list of differentially expressed KM high vs KM low genes against the REACTOME curated gene set database using ClusterProfiler package
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52eb2629c57087ccdf7531fa25bf1bf6
https://doi.org/10.1158/0008-5472.22633287.v1
https://doi.org/10.1158/0008-5472.22633287.v1
Autor:
Nigel B. Jamieson, Colin W. Steele, Joanne Edwards, Paul G. Horgan, Owen J. Sansom, Andrew V. Biankin, Donald C. McMillan, Campbell S.D. Roxburgh, Colin Nixon, Antonia K. Roseweir, Jennifer Hay, Hester C. van Wyk, Jean A. Quinn, Lydia Melissourgou-Syka, Andrew J. Cameron, Assya Legrini, Holly Leslie, Kathryn A.F. Pennel, Colin S. Wood
Supplementary details regarding methods and materials
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c84d91b354ecd603c7bb4d3097c5852
https://doi.org/10.1158/0008-5472.22633293.v1
https://doi.org/10.1158/0008-5472.22633293.v1
Autor:
Nigel B. Jamieson, Colin W. Steele, Joanne Edwards, Paul G. Horgan, Owen J. Sansom, Andrew V. Biankin, Donald C. McMillan, Campbell S.D. Roxburgh, Colin Nixon, Antonia K. Roseweir, Jennifer Hay, Hester C. van Wyk, Jean A. Quinn, Lydia Melissourgou-Syka, Andrew J. Cameron, Assya Legrini, Holly Leslie, Kathryn A.F. Pennel, Colin S. Wood
SpatialDecon derived immune cell counts aggregated by Region, KM grade and KRAS status with pairwise comparison between groups. Mann-Whitney test used to determine statistical significance between groups
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58adec63ac2802bd346cb81495e87314
https://doi.org/10.1158/0008-5472.22633290
https://doi.org/10.1158/0008-5472.22633290