Zobrazeno 1 - 10
of 601
pro vyhledávání: '"Nigel, Mackman"'
Autor:
Ana T. A. Sachetto, Nigel Mackman
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/02041e3081e648e7a7be3dc09dbf4846
Autor:
Nigel Mackman, Ana T.A. Sachetto
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/3fc1efff434b4065b311b10122d83f4d
Autor:
Cornelia Englisch, Florian Moik, Johannes Thaler, Silvia Koder, Nigel Mackman, Matthias Preusser, Ingrid Pabinger, Cihan Ay
Publikováno v:
Haematologica, Vol 109, Iss 4 (2023)
Venous thromboembolism (VTE) is a common complication in patients with cancer. Data on the role of natural inhibitors of coagulation for occurrence of cancer-associated VTE are limited, thus, we investigated the association of tissue factor pathway i
Externí odkaz:
https://doaj.org/article/70622f744d904a23ac4e6d653ee1fe29
Autor:
Michael F. Bode, Clare M. Schmedes, Grant J. Egnatz, Vanthana Bharathi, Yohei M. Hisada, David Martinez, Tomohiro Kawano, Alice Weithauser, Leah Rosenfeldt, Ursula Rauch, Joseph S. Palumbo, Silvio Antoniak, Nigel Mackman
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Protease-activated receptor 1 (PAR1) is widely expressed in humans and mice, and is activated by a variety of proteases, including thrombin. Recently, we showed that PAR1 contributes to the innate immune response to viral infection. Mice wit
Externí odkaz:
https://doaj.org/article/2196c66abee14dc480f8af601153009b
Autor:
Shu Yamakage, Yuji Oe, Emiko Sato, Koji Okamoto, Akiyo Sekimoto, Satoshi Kumakura, Hiroshi Sato, Mai Yoshida, Tasuku Nagasawa, Mariko Miyazaki, Sadayoshi Ito, Nigel Mackman, Nobuyuki Takahashi
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Patients with chronic kidney disease (CKD) commonly exhibit hypercoagulability. Increased levels of uremic toxins cause thrombogenicity by increasing tissue factor (TF) expression and activating the extrinsic coagulation cascade. TF is induc
Externí odkaz:
https://doaj.org/article/417c4d56cb9f41a1a7c5ffd5485b6f48
Autor:
Robert A. Ariëns, Beverley J. Hunt, Ejaife O. Agbani, Josefin Ahnström, Robert Ahrends, Raza Alikhan, Alice Assinger, Zsuzsa Bagoly, Alessandra Balduini, Elena Barbon, Christopher D. Barrett, Paul Batty, Jorge David Aivazoglou Carneiro, Wee Shian Chan, Moniek deMaat, Kerstin deWit, Cécile Denis, Martin H. Ellis, Renee Eslick, Hongxia Fu, Catherine P. M. Hayward, Benoit Ho‐Tin‐Noé, Frederikus A. Klok, Riten Kumar, Karin Leiderman, Rustem I. Litvinov, Nigel Mackman, Zoe McQuilten, Matthew D. Neal, William A. E. Parker, Roger J. S. Preston, Julie Rayes, Alireza R. Rezaie, Lara N. Roberts, Bianca Rocca, Susan Shapiro, Deborah M. Siegal, Lirlândia P. Sousa, Katsue Suzuki‐Inoue, Tahira Zafar, Jiaxi Zhou
Publikováno v:
Research and Practice in Thrombosis and Haemostasis, Vol 6, Iss 5, Pp n/a-n/a (2022)
Abstract The ISTH London 2022 Congress is the first held (mostly) face‐to‐face again since the COVID‐19 pandemic took the world by surprise in 2020. For 2 years we met virtually, but this year’s in‐person format will allow the ever‐so‐i
Externí odkaz:
https://doaj.org/article/f79ff8eebaef425b98250762e3be6774
Autor:
Steven P. Grover, Nigel Mackman
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
Appropriate activation of coagulation requires a balance between procoagulant and anticoagulant proteins in blood. Loss in this balance leads to hemorrhage and thrombosis. A number of endogenous anticoagulant proteins, such as antithrombin and hepari
Externí odkaz:
https://doaj.org/article/0a3cd870983d4d11935e03d6530660bb
Autor:
Silvio Antoniak, Nigel Mackman
Publikováno v:
Platelets, Vol 32, Iss 3, Pp 325-330 (2021)
Platelets play an essential role in maintaining vascular integrity after injury. In addition, platelets contribute to the immune response to pathogens. For instance, they express receptors that mediate binding of viruses, and toll-like receptors that
Externí odkaz:
https://doaj.org/article/8bddbf41e3ec473187ffbeb6050cdc28
Autor:
Axel Rosell, Katherina Aguilera, Yohei Hisada, Clare Schmedes, Nigel Mackman, Håkan Wallén, Staffan Lundström, Charlotte Thålin
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract Predicting survival accurately in patients with advanced cancer is important in guiding interventions and planning future care. Objective tools are therefore needed. Blood biomarkers are appealing due to their rapid measurement and objective
Externí odkaz:
https://doaj.org/article/6878c987d3634635982d478f171288b0
Autor:
Fien A. vonMeijenfeldt, Sebastian Havervall, Jelle Adelmeijer, Annika Lundström, Ann‐Sofie Rudberg, Maria Magnusson, Nigel Mackman, Charlotte Thalin, Ton Lisman
Publikováno v:
Research and Practice in Thrombosis and Haemostasis, Vol 5, Iss 1, Pp 132-141 (2021)
Abstract Background and Aims Patients with severe coronavirus disease 2019 (COVID‐19) are at significant risk of thrombotic complications. However, their prothrombotic state is incompletely understood. Therefore, we measured in vivo activation mark
Externí odkaz:
https://doaj.org/article/bdc4ab05fd334b419099c41a75635090