Oxygen-enhanced MRI and radiotherapy in patients with oropharyngeal squamous cell carcinoma

Autor: Emma Bluemke, Ambre Bertrand, Kwun-Ye Chu, Nigar Syed, Andrew G. Murchison, Rosie Cooke, Tessa Greenhalgh, Brian Burns, Martin Craig, Nia Taylor, Ketan Shah, Fergus Gleeson, Daniel Bulte

Publikováno v: Clinical and Translational Radiation Oncology, Vol 39, Iss , Pp 100563- (2023)

Background and purpose: This study aimed to assess the role of T1 mapping and oxygen-enhanced MRI in patients undergoing radical dose radiotherapy for HPV positive oropharyngeal cancer, which has not yet been examined in an OE-MRI study. Materials an

Externí odkaz: https://doaj.org/article/fb78570ab45f4b82bba427125458114f

Supplementary Information from Functional Parameters Derived from Magnetic Resonance Imaging Reflect Vascular Morphology in Preclinical Tumors and in Human Liver Metastases

Autor: Veerle Kersemans, Ricky A. Sharma, Mike Partridge, Ruth J. Muschel, Adrian L. Harris, Tim Maughan, Julia A. Schnabel, Sean Smart, Stuart Gilchrist, Paul Kinchesh, Bosjtan Markelc, Jakob Kaeppler, Bartlomiej W. Papiez, Benjamin Irving, Nigar Syed, Philip D. Allen, Russell Bates, Daniel Warren, Helen Winter, Warren W. Kretzschmar, Pavitra Kannan

Supplementary methods and data. Supplementary Table 1. Equations of chosen models fit using ordinary least squares regression with the best Bayesian Information Criterion for iAUC90, Ktrans, and BATfrac in untreated preclinical tumors (cohort 1). Goo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57976c059b7a53d0abb5e6c056d2f328
https://doi.org/10.1158/1078-0432.22470495.v1

The impact of radiobiologically-informed dose prescription on the clinical benefit of yttrium-90 SIRT in colorectal cancer patients

Autor: Nadia Falzone, Christiana Kartsonaki, Philip Boardman, Ricky A. Sharma, Katherine A. Vallis, Tessa A Greenhalgh, Nigar Syed, Daniel R. McGowan, Elliot M Abbott, Helen Winter, Ana M. Denis-Bacelar, B.Q. Lee

The purpose of this study was to establish the dose-response relationship of selective internal radiation therapy (SIRT) in patients with metastatic colorectal cancer (mCRC), when informed by radiobiological sensitivity parameters derived from mCRC c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d524864e1568ac7444555766de8baca6
https://ora.ox.ac.uk/objects/uuid:cb2c5707-16e4-4f57-8c4d-eb4ba17b4505

Functional parameters derived from magnetic resonance imaging reflect vascular morphology in preclinical tumors and in human liver metastases

Autor: Benjamin Irving, Stuart Gilchrist, Bartlomiej W. Papiez, Pavitra Kannan, Paul Kinchesh, Daniel R Warren, Nigar Syed, Sean Smart, Warren W. Kretzschmar, Ricky A. Sharma, Helen Winter, Philip D. Allen, Mike Partridge, Julia A. Schnabel, Veerle Kersemans, Bostjan Markelc, Jakob Kaeppler, Ruth J. Muschel, Russell Bates, Adrian L. Harris, Tim Maughan

Publikováno v: Kannan, P, Kretzschmar, W W, Winter, H, Warren, D R, Bates, R, Allen, P D, Syed, N, Irving, B, Papież, B W, Kaeppler, J, Markelc, B, Kinchesh, P, Gilchrist, S, Smart, S C, Schnabel, J A, Maughan, T S, Harris, A L, Muschel, R J, Partridge, M, Sharma, R A & Kersemans, V 2018, ' Functional parameters derived from magnetic resonance imaging reflect vascular morphology in preclinical tumors and in human liver metastases ', Clinical Cancer Research . https://doi.org/10.1158/1078-0432.CCR-18-0033

Purpose: Tumor vessels influence the growth and response of tumors to therapy. Imaging vascular changes in vivo using dynamic contrast-enhanced MRI (DCE-MRI) has shown potential to guide clinical decision making for treatment. However, quantitative M

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efdd5905f31dc980e7b7a9238359f967
https://europepmc.org/articles/PMC6171743/