Zobrazeno 1 - 10 of 41 pro vyhledávání: '"Nieves Rodríguez Henche"'
1
Akademický článek
Targeting AMP‐activated kinase impacts hepatocellular cancer stem cells induced by long‐term treatment with sorafenib
Autor: Alicia Bort, Belén G. Sánchez, Pedro A. Mateos‐Gómez, Diana Vara‐Ciruelos, Nieves Rodríguez‐Henche, Inés Díaz‐Laviada
Publikováno v: Molecular Oncology, Vol 13, Iss 5, Pp 1311-1331 (2019)
Hepatocellular carcinoma (HCC) is the third leading cause of cancer death worldwide. HCC treatment is hindered by the frequent emergence of chemoresistance to the multikinase inhibitor sorafenib, which has been related to the presence of cancer stem
Externí odkaz: https://doaj.org/article/e8408f6e3e2247afa66d7c76d863ded4
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2
Akademický článek
Combination of the natural product capsaicin and docetaxel synergistically kills human prostate cancer cells through the metabolic regulator AMP-activated kinase
Autor: Belén G. Sánchez, Alicia Bort, Pedro A. Mateos-Gómez, Nieves Rodríguez-Henche, Inés Díaz-Laviada
Publikováno v: Cancer Cell International, Vol 19, Iss 1, Pp 1-14 (2019)
Abstract Background Current chemotherapy for castration-resistant prostate cancer is established on taxane-based compounds like docetaxel. However, eventually, the development of toxic side effects and resistance limits the therapeutic benefit being
Externí odkaz: https://doaj.org/article/d20b7b4fc2d54d669631da9dc77519d5
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3
Akademický článek
The red pepper's spicy ingredient capsaicin activates AMPK in HepG2 cells through CaMKKβ.
Autor: Alicia Bort, Belén G Sánchez, Elena Spínola, Pedro A Mateos-Gómez, Nieves Rodríguez-Henche, Inés Díaz-Laviada
Publikováno v: PLoS ONE, Vol 14, Iss 1, p e0211420 (2019)
Capsaicin is a natural compound present in chili and red peppers and the responsible of their spicy flavor. It has recently provoked interest because of its antitumoral effects in many cell types although its action mechanism is not clearly understoo
Externí odkaz: https://doaj.org/article/4a11297523a343c991573d5a09d49e7b
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7
Akademický článek
Up-Regulated Expression of LAMP2 and Autophagy Activity during Neuroendocrine Differentiation of Prostate Cancer LNCaP Cells.
Autor: Cecilia Morell, Alicia Bort, Diana Vara-Ciruelos, Ágata Ramos-Torres, Manuel Altamirano-Dimas, Inés Díaz-Laviada, Nieves Rodríguez-Henche
Publikováno v: PLoS ONE, Vol 11, Iss 9, p e0162977 (2016)
Neuroendocrine (NE) prostate cancer (PCa) is a highly aggressive subtype of prostate cancer associated with resistance to androgen ablation therapy. In this study, we used LNCaP prostate cancer cells cultured in a serum-free medium for 6 days as a NE
Externí odkaz: https://doaj.org/article/6d133d84d13c4a479c58975617f7497e
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8
Akademický článek
Novel cancer chemotherapy hits by molecular topology: dual Akt and Beta-catenin inhibitors.
Autor: Riccardo Zanni, Maria Galvez-Llompart, Cecilia Morell, Nieves Rodríguez-Henche, Inés Díaz-Laviada, Maria Carmen Recio-Iglesias, Ramon Garcia-Domenech, Jorge Galvez
Publikováno v: PLoS ONE, Vol 10, Iss 4, p e0124244 (2015)
Background and purposeColorectal and prostate cancers are two of the most common types and cause of a high rate of deaths worldwide. Therefore, any strategy to stop or at least slacken the development and progression of malignant cells is an importan
Externí odkaz: https://doaj.org/article/dcab84bd48f3458da4ed03dfab5117b4
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9
Combination of the natural product capsaicin and docetaxel synergistically kills human prostate cancer cells through the metabolic regulator AMP-activated kinase
Autor: Pedro A. Mateos-Gómez, Nieves Rodríguez-Henche, Alicia Bort, Inés Díaz-Laviada, Belén G. Sánchez
Publikováno v: Cancer Cell International, Vol 19, Iss 1, Pp 1-14 (2019)
Cancer Cell International
Background Current chemotherapy for castration-resistant prostate cancer is established on taxane-based compounds like docetaxel. However, eventually, the development of toxic side effects and resistance limits the therapeutic benefit being the major
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::884e627dd199e89ddfbf686aa8690897
http://link.springer.com/article/10.1186/s12935-019-0769-2
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