Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Nieves M, Gabrielli"'
Autor:
Nieves M. Gabrielli, Luciana C. Mazzocchi, Vitalii Kryvenko, Khodr Tello, Susanne Herold, Rory E. Morty, Friedrich Grimminger, Laura A. Dada, Werner Seeger, Jacob I. Sznajder, István Vadász
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Several acute and chronic lung diseases are associated with alveolar hypoventilation leading to accumulation of CO2 (hypercapnia). The β-subunit of the Na,K-ATPase plays a pivotal role in maintaining epithelial integrity by functioning as a cell adh
Externí odkaz:
https://doaj.org/article/be568d9bd36f4d7cb23b5118e3ec3871
Autor:
Elmira, Tokhtaeva, Haying, Sun, Nimrod, Deiss-Yehiely, Yi, Wen, Pritin N, Soni, Nieves M, Gabrielli, Elizabeth A, Marcus, Karen M, Ridge, George, Sachs, Mónica, Vazquez-Levin, Jacob I, Sznajder, Olga, Vagin, Laura A, Dada
Publikováno v:
Journal of cell science. 129(12)
FXYD5 (also known as dysadherin), a regulatory subunit of the Na,K-ATPase, impairs intercellular adhesion by a poorly understood mechanism. Here, we determined whether FXYD5 disrupts the trans-dimerization of Na,K-ATPase molecules located in neighbor
Autor:
Werner Seeger, Christine U. Vohwinkel, Susanne Herold, Rory E. Morty, Yasmin Buchäckert, Benno Grzesik, Sebastian Rummel, István Vadász, Nieves M. Gabrielli, Konstantin Mayer
Publikováno v:
The Journal of Physiology. 590:5167-5181
Key points • Under physiological conditions the lung alveoli are impermeable to protein. • In patients with acute lung injury/acute respiratory distress syndrome (ALI/ARDS) protein-rich oedema fluid accumulates in the distal airspaces and leads t
Publikováno v:
American journal of physiology. Lung cellular and molecular physiology. 305(10)
In this review we summarize recent major advances in our understanding on the molecular mechanisms, mediators, and biomarkers of acute lung injury (ALI) and alveolar-capillary barrier dysfunction, highlighting the role of immune cells, inflammatory a