Výsledky vyhledávání - "Nievergelt, CM"

HIGH AND LOW THRESHOLD FOR STARTLE REACTIVITY ASSOCIATED WITH PTSD SYMPTOMS BUT NOT PTSD RISK: EVIDENCE FROM A PROSPECTIVE STUDY OF ACTIVE DUTY MARINES

Autor: Glenn, DE, Acheson, DT, Geyer, MA, Nievergelt, CM, Baker, DG, Risbrough, VB, Team, MRS

Publikováno v: Depression and anxiety, vol 33, iss 3
Glenn, DE; Acheson, DT; Geyer, MA; Nievergelt, CM; Baker, DG; Risbrough, VB; et al.(2016). HIGH AND LOW THRESHOLD FOR STARTLE REACTIVITY ASSOCIATED WITH PTSD SYMPTOMS BUT NOT PTSD RISK: EVIDENCE FROM A PROSPECTIVE STUDY OF ACTIVE DUTY MARINES. DEPRESSION AND ANXIETY, 33(3), 192-202. doi: 10.1002/da.22475. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/77s696sk

BackgroundHeightened startle response is a symptom of PTSD, but evidence for exaggerated startle in PTSD is inconsistent. This prospective study aimed to clarify whether altered startle reactivity represents a trait risk-factor for developing PTSD or

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https://escholarship.org/uc/item/77s696sk

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Biogeographic Ancestry in the African Descent and Glaucoma Evaluation Study (ADAGES): Association With Corneal and Optic Nerve Structure

Autor: Girkin, CA, Nievergelt, CM, Kuo, JZ, Maihofer, AX, Huisingh, C, Liebmann, JM, Ayyagari, R, Weinreb, RN, Ritch, R, Zangwill, LM, Grp, ADAGESS

Publikováno v: Investigative ophthalmology & visual science, vol 56, iss 3
Girkin, CA; Nievergelt, CM; Kuo, JZ; Maihofer, AX; Huisingh, C; Liebmann, JM; et al.(2015). Biogeographic Ancestry in the African Descent and Glaucoma Evaluation Study (ADAGES): Association With Corneal and Optic Nerve Structure. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 56(3), 2043-2049. doi: 10.1167/iovs.14-15719. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/3zz7n3p3

PurposeWe determined if quantitative measurements of biogeographic ancestry (BGA) correlate with variations in optic disc area, corneal thickness (CCT), and retinal nerve fiber layer (RNFL) thickness.MethodsData were obtained from 656 participants in

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https://escholarship.org/uc/item/3zz7n3p3

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Blood-based gene-expression biomarkers of post-traumatic stress disorder among deployed marines: A pilot study

Publikováno v: Tylee, DS; Chandler, SD; Nievergelt, CM; Liu, X; Pazol, J; Woelk, CH; et al.(2015). Blood-based gene-expression biomarkers of post-traumatic stress disorder among deployed marines: A pilot study. Psychoneuroendocrinology, 51, 472-494. doi: 10.1016/j.psyneuen.2014.09.024. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/7wb4k616

© 2014 Elsevier Ltd. The etiology of post-traumatic stress disorder (PTSD) likely involves the interaction of numerous genes and environmental factors. Similarly, gene-expression levels in peripheral blood are influenced by both genes and environmen

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http://www.escholarship.org/uc/item/7wb4k616

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Diagnostic Utility of the Posttraumatic Stress Disorder (PTSD) Checklist for Identifying Full and Partial PTSD in Active-Duty Military

Autor: Dickstein, BD, Weathers, FW, Angkaw, AC, Nievergelt, CM, Yurgil, K, Nash, WP, Baker, DG, Litz, BT

Publikováno v: Dickstein, BD; Weathers, FW; Angkaw, AC; Nievergelt, CM; Yurgil, K; Nash, WP; et al.(2015). Diagnostic Utility of the Posttraumatic Stress Disorder (PTSD) Checklist for Identifying Full and Partial PTSD in Active-Duty Military. Assessment, 22(3), 289-297. doi: 10.1177/1073191114548683. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/2qn0c1f7

© The Author(s) 2014. The aim of this study was to determine optimally efficient cutoff scores on the Posttraumatic Stress Disorder Checklist (PCL) for identifying full posttraumatic stress disorder (PTSD) and partial PTSD (P-PTSD) in active-duty Ma

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http://www.escholarship.org/uc/item/2qn0c1f7

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Conditioned fear and extinction learning performance and its association with psychiatric symptoms in active duty Marines

Autor: Acheson, DT, Geyer, MA, Baker, DG, Nievergelt, CM, Yurgil, K, Risbrough, VB, MRS-II Team

BackgroundPosttraumatic Stress Disorder (PTSD) is a major public health concern, especially given the recent wars in Iraq and Afghanistan. Nevertheless, despite a sharp increase in the incidence of psychiatric disorders in returning veterans, empiric

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https://escholarship.org/uc/item/28s459p8

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Assessment of plasma C-Reactive protein as a biomarker of posttraumatic stress disorder risk

Autor: Eraly, SA, Nievergelt, CM, Maihofer, AX, Barkauskas, DA, Biswas, N, Agorastos, A, O'Connor, DT, Baker, DG

Publikováno v: Eraly, SA; Nievergelt, CM; Maihofer, AX; Barkauskas, DA; Biswas, N; Agorastos, A; et al.(2014). Assessment of plasma C-Reactive protein as a biomarker of posttraumatic stress disorder risk. JAMA Psychiatry, 71(4), 423-431. doi: 10.1001/jamapsychiatry.2013.4374. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/17c8r6x1

IMPORTANCE Posttraumatic stress disorder (PTSD) has been associated in cross-sectional studies with peripheral inflammation. It is not known whether this observed association is the result of PTSD predisposing to inflammation (as sometimes postulated

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http://www.escholarship.org/uc/item/17c8r6x1

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Association between traumatic brain injury and risk of posttraumatic stress disorder in active-duty marines

Autor: Yurgil, KA, Barkauskas, DA, Vasterling, JJ, Nievergelt, CM, Larson, GE, Schork, NJ, Litz, BT, Nash, WP, Baker, DG

Publikováno v: Yurgil, KA; Barkauskas, DA; Vasterling, JJ; Nievergelt, CM; Larson, GE; Schork, NJ; et al.(2014). Association between traumatic brain injury and risk of posttraumatic stress disorder in active-duty marines. JAMA Psychiatry, 71(2), 149-157. doi: 10.1001/jamapsychiatry.2013.3080. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/982232r7

Importance Whether traumatic brain injury (TBI) is a risk factor for posttraumatic stress disorder (PTSD) has been difficult to determine because of the prevalence of comorbid conditions, overlapping symptoms, and cross-sectional samples. OBJECTIVE T

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Enrichment of cis-regulatory gene expression SNPs and methylation quantitative trait loci among bipolar disorder susceptibility variants

Autor: Byerley, William, Gamazon, ER, Badner, JA, Cheng, L, Zhang, C, Zhang, D, Cox, NJ, Gershon, ES, Kelsoe, JR, Greenwood, TA, Nievergelt, CM

Publikováno v: Byerley, William; Gamazon, ER; Badner, JA; Cheng, L; Zhang, C; Zhang, D; et al.(2013). Enrichment of cis-regulatory gene expression SNPs and methylation quantitative trait loci among bipolar disorder susceptibility variants. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/9t47m5fh

We conducted a systematic study of top susceptibility variants from a genome-wide association (GWA) study of bipolar disorder to gain insight into the functional consequences of genetic variation influencing disease risk. We report here the results o

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http://www.escholarship.org/uc/item/9t47m5fh

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Functional genetic variation in the Rev-Erbα pathway and lithium response in the treatment of bipolar disorder

Autor: McCarthy, MJ, Nievergelt, CM, Shekhtman, T, Kripke, DF, Welsh, DK, Kelsoe, JR

Publikováno v: Genes, brain, and behavior, vol 10, iss 8
Mccarthy, MJ; Nievergelt, CM; Shekhtman, T; Kripke, DF; Welsh, DK; & Kelsoe, JR. (2011). Functional genetic variation in the Rev-Erbα pathway and lithium response in the treatment of bipolar disorder. Genes, Brain and Behavior, 10(8), 852-861. doi: 10.1111/j.1601-183X.2011.00725.x. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/0jb7q8tj

Bipolar disorder (BD) is characterized by disruptions in circadian rhythms such as sleep and daily activity that often normalize after lithium treatment in responsive patients. As lithium is known to interact with the circadian clock, we hypothesized

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