Cholangiocarcinoma progression depends on the uptake and metabolization of extracellular lipids

Autor: Mikel Ruiz de Gauna, Francesca Biancaniello, Francisco González‐Romero, Pedro M. Rodrigues, Ainhoa Lapitz, Beatriz Gómez‐Santos, Paula Olaizola, Sabina Di Matteo, Igor Aurrekoetxea, Ibone Labiano, Ane Nieva‐Zuluaga, Asier Benito‐Vicente, María J. Perugorria, Maider Apodaka‐Biguri, Nuno A. Paiva, Diego Sáenz de Urturi, Xabier Buqué, Igotz Delgado, César Martín, Mikel Azkargorta, Felix Elortza, Diego F. Calvisi, Jesper B. Andersen, Domenico Alvaro, Vincenzo Cardinale, Luis Bujanda, Jesús M. Banales, Patricia Aspichueta

Publikováno v: Ruiz de Gauna, M, Biancaniello, F, González-Romero, F, Rodrigues, P M, Lapitz, A, Gómez-Santos, B, Olaizola, P, Di Matteo, S, Aurrekoetxea, I, Labiano, I, Nieva-Zuluaga, A, Benito-Vicente, A, Perugorria, M J, Apodaka-Biguri, M, Paiva, N A, Sáenz de Urturi, D, Buqué, X, Delgado, I, Martín, C, Azkargorta, M, Elortza, F, Calvisi, D F, Andersen, J B, Alvaro, D, Cardinale, V, Bujanda, L, Banales, JM & Aspichueta, P 2022, ' Cholangiocarcinoma progression depends on the uptake and metabolization of extracellular lipids ', Hepatology, vol. 76, no. 6, pp. 1617-1633 . https://doi.org/10.1002/hep.32344

[Background and Aims] Cholangiocarcinoma (CCA) includes a heterogeneous group of biliary cancers with a dismal prognosis. We investigated if lipid metabolism is disrupted in CCA and its role in tumor proliferation.
[Approach and Results] The in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78325d0133d0e5293fd2e7b3e6a39a25
http://hdl.handle.net/10261/304495

TOP-229-YI The E2F2 target glycerophosphodiester phosphodiesterase domain containing 3 is involved in MASLD progression to HCC and related dyslipidemias

Autor: Apodaka-Biguri, Maider, Muñoz-Llanes, Nerea, Gonzalez-Romero, Francisco, Aurrekoetxea, Igor, Santos, Beatriz Gómez, Delgado, Igotz, Buque, Xabier, Nieva-Zuluaga, Ane, de Gauna, Mikel Ruiz, Fernández-Puertas, Idoia, Gomez-Jauregui, Paul, Sainz-Ramírez, Natalia, Alfaro-Jiménez, Kendall, Castillero, Estibaliz, Congregado, Daniela Mestre, Woodhoo, Ashwin, Varela-Rey, Marta, Lujambio, Amaia, Zubiaga, Ana, Aspichueta, Patricia

Publikováno v: In Journal of Hepatology June 2024 80 Supplement 1:S562-S562

FRI-343-YI APAP induced liver damage is prevented by activation of PPARgamma and PPAR-alpha

Autor: Gomez-Jauregui, Paul, Gonzalez-Romero, Francisco, Santos, Beatriz Gómez, Apodaka-Biguri, Maider, Buque, Xabier, Crespo, Maria, Mora, Alfonso, Mesquita, Mariana, Aurrekoetxea, Igor, Delgado, Igotz, Nieva-Zuluaga, Ane, de Gauna, Mikel Ruiz, Fernández-Puertas, Idoia, Sainz-Ramírez, Natalia, Alfaro-Jiménez, Kendall, Irizar, María Esther, Iglesias, Ainhoa, Cubero, Francisco Javier, Sabio, Guadalupe, Zubiaga, Ana, Aspichueta, Patricia

Publikováno v: In Journal of Hepatology June 2024 80 Supplement 1:S112-S113

miR34a-5p is a target of E2F2 transcription factor in MAFLD-related HCC

Autor: Maider Apodaka-Biguri, Francisco Gonzalez-Romero, Daniela Mestre Congregado, Igor Aurrekoetxea, Beatriz Gómez Santos, Igotz Delgado, Xabier Buque, Ane Nieva-Zuluaga, Mikel Ruiz de Gauna, Idoia Fernámdez-Puertas, Ainhoa Iglesias, Ana María Aransay, Juanjo Lozano, Cesar Augusto Martín, Irantzu Bernales, Ana Zubiaga, Patricia Aspichueta

Publikováno v: Journal of Hepatology. 77:S651-S652

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::34a53d5704014a1879679ec49e53bf9f
https://doi.org/10.1016/s0168-8278(22)01618-x

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