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pro vyhledávání: '"Niessen Kyle Steven"'
Autor:
Rosemary J. Akhurst, Bahar Zivak, Eswari Dodagatta-Marri, John T. Li, Niessen Kyle Steven, Bing Yang, Szu-Ying Chen, Joselyn S. Del Cid, Dean Sheppard, Michael Rosenblum, Benjia Liang, Dominique S. Meyer, Tatsuya Tsukui, Anand Giddabasappa, Hsiao-Yen Ma, Lauren Pinzas, Sharon Yang, Mark B. Headley, Kai-Hui Sun, Nilgun Isik Reed, Xin Ren, Joseph Dal Porto, Kavon Noorbehesht, Amha Atakilit, Byron Hann
Publikováno v:
Cell reports
SUMMARY αvβ8 integrin, a key activator of transforming growth factor β (TGF-β), inhibits anti-tumor immunity. We show that a potent blocking monoclonal antibody against αvβ8 (ADWA-11) causes growth suppression or complete regression in syngenei
Autor:
Maeva Adoumie, Joselyn S. Del Cid, Dean Sheppard, Tatsuya Tsukui, Lauren Pinzas, Eswari Dodagatta-Marri, Xin Ren, John T. Li, Sharon Yang, Niessen Kyle Steven, Bing Yang, Anand Giddabasappa, Mark B. Headley, Benjia Liang, Kai-Hui Sun, Nilgun Isik Reed, Hsiao-Yen Ma, Bahar Zivak, Dominique S. Meyer, Rosemary J. Akhurst, Michael Rosenblum, Amha Atakilit, Kavon Noorbehesht, Byron Hann, Joseph Dal Porto
The αvβ8 integrin is a key activator of transforming growth factor β (TGF β), which has been shown to inhibit anti-tumor immunity. Previous work has suggested that αvβ8 on tumor cells could modulate tumor growth and responses to immune checkpoi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ff1856d50cc8a87bd543566bac9f47b
https://doi.org/10.1101/2020.05.14.084913
https://doi.org/10.1101/2020.05.14.084913
Autor:
Bahar Zivak, Dominique S. Meyer, John T. Li, Rosemary J. Akhurst, Nilgun Isik Reed, Eswari Dodagatta-Marri, Mark B. Headley, Anand Giddabasappa, Kai-Hui Sun, Niessen Kyle Steven, Bing Yang, Sharon Yang, Joselyn S. Del Cid, Dean Sheppard, Maeva Adoumie, Michael Rosenblum, Tatsuya Tsukui, Hsiao-Yen Ma, Amha Atakilit, Xin Ren, Kavon Noorbehesht, Joseph Dal Porto, Byron Hann, Benjia Liang, Lauren Pinzas
Publikováno v:
SSRN Electronic Journal.
The αvβ8 integrin is a key activator of transforming growth factor β(TGFβ), which has been shown to inhibit anti-tumor immunity. Previous work has suggested that αvβ8 on tumor cells could modulate tumor growth and responses to immune checkpoint