Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Nienwen Chow"'
Autor:
Nienwen Chow, J. H. David Wu
Enzymatic degradation of plant biomass is carried out by a myriad of cellulases and hemicellulases. Complete hydrolysis of crystalline cellulose is facilitated by the synergistic action between endo- and exo-β-glucanases. Although most biomass-degra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::62d92e6c30c7cde6b67a137feabfaa24
https://doi.org/10.1016/b978-0-12-803725-6.00010-8
https://doi.org/10.1016/b978-0-12-803725-6.00010-8
Autor:
Erika Cristina G. Aguieiras, Miguel Alcalde, Miguel Arroyo, Rafael Bargiela, José-Luis Barredo, Sudhanshu S. Behera, Jenny M. Blamey, Elba P.S. Bon, Adelar Bracht, Goutam Brahmachari, Felipe Calzado, Magali C. Cammarota, Filipe Carvalho, Nienwen Chow, Fabiano Jares Contesini, Rúbia Carvalho Gomes Côrrea, Ayla Sant’Ana da Silva, Bruna Polacchine da Silva, Isabel de la Mata, Ricardo Rodrigues de Melo, Livian Ribeiro Vasconcelos de Sá, Marcella Fernandes de Souza, Karel De Winter, Arnold L. Demain, Tom Desmet, Guocheng Du, Pedro Fernandes, Viridiana S. Ferreira-Leitão, Manuel Ferrer, Fabian Fischer, Denise M.G. Freire, José-Luis García, Patricia Gomez de Santos, David Gonzalez-Perez, Kohsuke Honda, Shigenori Kanaya, Camila Gabriel Kato, Yuichi Koga, Chandrakant Kokare, Jianghua Li, Paloma Liras, Long Liu, Xiangyang Liu, Danielle Branta Lopes, Jose Valdo Madeira, Juan F. Martín, Mónica Martínez-Martínez, Diana M. Mate, Ivan Mateljak, Hans-Peter Meyer, Ashok Pandey, Anil Kumar Patel, Rosane Marina Peralta, Ramesh C. Ray, Diana Rocha, Alba Romero, Marcelo Ventura Rubio, Beatriz Ruiz-Villafán, Sergio Sanchez, Felipe Sarmiento, Flávio Augusto Vicente Seixas, Reeta Rani Singhania, Kazufumi Takano, Ricardo Sposina Sobral Teixeira, Ryo Uehara, Tom Verhaeghe, Ana Isabel Vicente, J. H. David Wu, Haiquan Yang, Manfred Zinn, Mariane Paludetti Zubieta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5d4c7b10e77db9c566af3a2accb94ab7
https://doi.org/10.1016/b978-0-12-803725-6.00028-5
https://doi.org/10.1016/b978-0-12-803725-6.00028-5
Autor:
Nienwen Chow, Frederick J. Marshall, Richard J. Caselli, Marwan N. Sabbagh, Eric M. Reiman, Jennifer Nolz, Elaine Delvaux, Diego Mastroeni, Paul D. Coleman
Publikováno v:
Neurobiology of Aging, 58, 225-237. Elsevier Science
The need for a reliable, simple, and inexpensive blood test for Alzheimer's disease (AD) suitable for use in a primary care setting is widely recognized. This has led to a large number of publications describing blood tests for AD, which have, for th
Autor:
John H. Griffin, Patrick D. Lyden, Berislav V. Zlokovic, Zhen Zhao, Yaoming Wang, Nienwen Chow, Padmesh S. Rajput
Publikováno v:
Stroke. 44:3529-3536
Background and Purpose— 3K3A-activated protein C (APC) protects young, healthy male rodents after ischemic stroke. 3K3A-APC is currently under development as a neuroprotectant for acute ischemic stroke in humans. Stroke Therapy Academic Industry Ro
Autor:
Huang Guo, Robert D. Bell, Su Wang, Berislav V. Zlokovic, Nienwen Chow, Steven A. Goldman, Zhen Zhao, Thomas P. Davis, John H. Griffin, Qi Yang, Min Wang
Publikováno v:
The Journal of Neuroscience. 33:6181-6190
Activated protein C (APC) is a protease with anticoagulant and cell-signaling activities. In the CNS, APC and its analogs with reduced anticoagulant activity but preserved cell signaling activities, such as 3K3A-APC, exert neuroprotective, vasculopro
Publikováno v:
Brain Research. 1507:97-104
3K3A-APC is a recombinant analog of activated protein C (APC) which is an endogenous protease with multiple functions in the body. Compared to APC, 3K3A-APC has reduced anticoagulant activity but preserved cell signaling activities. In the brain, 3K3
Autor:
Berislav V. Zlokovic, Nienwen Chow, Zhenggang Zhang, John H. Griffin, Thomas P. Davis, Michael Chopp, Yaoming Wang
Publikováno v:
Stroke. 43:2444-2449
Background and Purpose— Tissue plasminogen activator (tPA) is the only approved therapy for acute ischemic stroke. However, tPA has a brief therapeutic window. Its side effects include intracerebral bleeding and neurotoxicity. Therefore, a combinat
Autor:
Theresa M Barrett, Itender Singh, Berislav V. Zlokovic, Huang Guo, José A. Fernández, Rashid Deane, John H. Griffin, Nienwen Chow, Yaoming Wang
Publikováno v:
European Journal of Neuroscience. 29:1119-1130
The anticoagulant activated protein C (APC) protects neurons and endothelium via protease activated receptor (PAR)1, PAR3 and endothelial protein C receptor. APC is neuroprotective in stroke models. Bleeding complications may limit the pharmacologic
Autor:
Nienwen Chow, Jeffrey W. Streb, Jiyuan Chen, Andrew I. Brooks, William E. Van Nostrand, Rashid Deane, Berislav V. Zlokovic, Robert D. Bell, Joseph M. Miano
Publikováno v:
Proceedings of the National Academy of Sciences. 104:823-828
Cerebral angiopathy contributes to cognitive decline and dementia in Alzheimer's disease (AD) through cerebral blood flow (CBF) reductions and dysregulation. We report vascular smooth muscle cells (VSMC) in small pial and intracerebral arteries, whic
Autor:
Rashid Deane, Anna Rubio, Jan Sallstrom, Fang Li, Zhenhua Wu, Florence M. Hofman, Andrew I. Brooks, Thomas A. Gasiewicz, Nienwen Chow, Suhasini Kanagala, Berislav V. Zlokovic, Dong Liu, Abhay P. Sagare, Raphael Zidovetzki, Don Armstrong, Robert D. Bell, Huang Guo, Xiaomei Song
Publikováno v:
Nature Medicine. 11:959-965
Neurovascular dysfunction substantially contributes to Alzheimer disease. Here, we show that transcriptional profiling of human brain endothelial cells (BECs) defines a subset of genes whose expression is age-independent but is considerably altered i