Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Nienke van Rooij"'
Autor:
Anneke L. Eerkens, Koen Brummel, Annegé Vledder, Sterre T. Paijens, Marta Requesens, Dominik Loiero, Nienke van Rooij, Annechien Plat, Floris-Jan Haan, Patty Klok, Refika Yigit, Thijs Roelofsen, Natascha M. de Lange, Rie Klomp, David Church, Arja ter Elst, René Wardenaar, Diana Spierings, Floris Foijer, Viktor Hendrik Koelzer, Tjalling Bosse, Joost Bart, Mathilde Jalving, Anna K. L. Reyners, Marco de Bruyn, Hans W. Nijman
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Neoadjuvant immune checkpoint blockade (ICB) has shown unprecedented activity in mismatch repair deficient (MMRd) colorectal cancers, but its effectiveness in MMRd endometrial cancer (EC) remains unknown. In this investigator-driven, phase I
Externí odkaz:
https://doaj.org/article/1b7aedf643dd44ed914769ada0de8d61
Autor:
Martijn Vlaming, Vrouyr Bilemjian, Jimena Álvarez Freile, Harm Jan Lourens, Nienke van Rooij, Gerwin Huls, Tom van Meerten, Marco de Bruyn, Edwin Bremer
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract The presence of T cells that are dimly positive for the B cell marker CD20 is well-established in autoimmunity and correlates with disease severity in various diseases. Further, we previously identified that the level of CD20-positive T cell
Externí odkaz:
https://doaj.org/article/5b0c52b51ccf44eb9aa17073f9d75dfd
Autor:
Hagma H. Workel, Nienke van Rooij, Annechien Plat, Diana C.J. Spierings, Rudolf S. N. Fehrmann, Hans W. Nijman, Marco de Bruyn
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 11, p 3770 (2020)
Tumor-infiltrating CD8+ T cells (TIL) are of the utmost importance in anti-tumor immunity. CD103 defines tumor-resident memory T cells (TRM cells) associated with improved survival and response to immune checkpoint blockade (ICB) across human tumors.
Externí odkaz:
https://doaj.org/article/973b2dff834643d89129dbabe2c71464
Autor:
Stephanie van de Wall, Mateusz Walczak, Nienke van Rooij, Baukje-Nynke Hoogeboom, Tjarko Meijerhof, Hans W. Nijman, Toos Daemen
Publikováno v:
Vaccines, Vol 3, Iss 2, Pp 221-238 (2015)
The skin is an attractive organ for immunization because of the presence of antigen-presenting cells. Intradermal delivery via tattooing has demonstrated superior vaccine immunogenicity of DNA vaccines in comparison to conventional delivery methods.
Externí odkaz:
https://doaj.org/article/16d3a377a40e4e5a9d935b562174666a
Autor:
Bettien M. van Hemel, Nienke van Rooij, Bart Koopman, Timco Koopman, Marco de Bruyn, Harry Pijper, Harry Hollema, Bea Wisman, Joyce M Lubbers, Jessica M de Klerk-Sluis, Hans W. Nijman, Annechien Plat
Publikováno v:
Cancer science, 112(1), 61-71. Wiley
Cancer Science
Cancer Science
DNA‐sensing receptor Cyclic GMP–AMP Synthase (cGAS) and its downstream signaling effector STimulator of INterferon Genes (STING) have gained significant interest in the field of tumor immunology, as a dysfunctional cGAS‐STING pathway is associa
Autor:
Joyce M. Lubbers, Marta A. Ważyńska, Nienke van Rooij, Arjan Kol, Hagma H. Workel, Annechien Plat, Sterre T. Paijens, Martijn R. Vlaming, Diana C. J. Spierings, Philip H. Elsinga, Edwin Bremer, Hans W. Nijman, Marco de Bruyn
Publikováno v:
Cancers, 14(8):1924. MDPI AG
Cancers; Volume 14; Issue 8; Pages: 1924
Cancers; Volume 14; Issue 8; Pages: 1924
Identification of human cancer-reactive CD8+ T cells is crucial for the stratification of patients for immunotherapy and determination of immune-therapeutic effects. To date, these T cells have been identified mainly based on cell surface expression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fba6a752dc959719d6c9dfef8d9b2b2
https://research.rug.nl/en/publications/1b60c38f-4cad-406a-9c62-f6ddb9811bc2
https://research.rug.nl/en/publications/1b60c38f-4cad-406a-9c62-f6ddb9811bc2
Autor:
Annechien Plat, Nienke van Rooij, Marco de Bruyn, Rudolf S N Fehrmann, Diana C.J. Spierings, Hans W. Nijman, Hagma H. Workel
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, 21(11):3770. MDPI AG
Volume 21
Issue 11
International Journal of Molecular Sciences, Vol 21, Iss 3770, p 3770 (2020)
International Journal of Molecular Sciences, 21(11):3770. MDPI AG
Volume 21
Issue 11
International Journal of Molecular Sciences, Vol 21, Iss 3770, p 3770 (2020)
Tumor-infiltrating CD8+ T cells (TIL) are of the utmost importance in anti-tumor immunity. CD103 defines tumor-resident memory T cells (TRM cells) associated with improved survival and response to immune checkpoint blockade (ICB) across human tumors.
Autor:
Sander Kelderman, Stieneke van den Brink, Ton N. Schumacher, Nienke van Rooij, Sovann Kaing, Lorenzo F. Fanchi, Emile E. Voest, Chiara M Cattaneo, Krijn K. Dijkstra
Publikováno v:
Nat Protoc
T cells are a key player in cancer immunotherapy, but strategies to expand tumor-reactive cells and study their interaction with tumor cells at the level of an individual patient are limited. This protocol describes the generation and functional asse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::010f51d68bb26e76f05cc6a1efdedd62
https://europepmc.org/articles/PMC7610702/
https://europepmc.org/articles/PMC7610702/
Antigen-specific TIL therapy for melanoma: A flexible platform for personalized cancer immunotherapy
Autor:
Lorenzo F. Fanchi, Sander Kelderman, Nienke van Rooij, Samira Michels, John B. A. G. Haanen, Mireille Toebes, Pia Kvistborg, Bianca Heemskerk, Marit M. van Buuren, N. M. Schumacher, Lothar Germeroth, Daisy Philips
Publikováno v:
European Journal of Immunology. 46:1351-1360
Tumor infiltrating lymphocyte (TIL) therapy has shown objective clinical response rates of 50% in stage IV melanoma patients in a number of clinical trials. Nevertheless, the majority of patients progress either directly upon therapy or after an init
Autor:
Mateusz Walczak, Stephanie van de Wall, Toos Daemen, Tjarko Meijerhof, Baukje Nynke Hoogeboom, Nienke van Rooij, Hans W. Nijman
Publikováno v:
Vaccines, Vol 3, Iss 2, Pp 221-238 (2015)
Vaccines, 3(2), 221-238. MDPI AG
Vaccines
Volume 3
Issue 2
Pages 221-238
Vaccines, 3(2), 221-238. MDPI AG
Vaccines
Volume 3
Issue 2
Pages 221-238
The skin is an attractive organ for immunization because of the presence of antigen-presenting cells. Intradermal delivery via tattooing has demonstrated superior vaccine immunogenicity of DNA vaccines in comparison to conventional delivery methods.