Effect of a soy isoflavone supplement on lung function and clinical outcomes in patients with poorly controlled asthma: a randomized clinical trial

Autor: Adante Hart, Samang Ung, Callan J. Burzynski, Susan Rappaport, Bennie McWilliams, Elizabeth Lancet, Sabrena Mervin-Blake, Michael O. Daines, Tara F. Carr, Jennifer Kustwin, David M. Shade, Nicholas Eberlein, Elise Pangborn, Connie Romaine, Ellen D. Brown, Patricia D. Rebolledo, Andre Rogatko, Anna Adler, Adam Wanner, Stephanie M. Burns, Jonathan Cruse, Deanna M. Green, Janette C. Priefert, Gail Weinmann, W. Gerald Teague, John Welter, Deborah Keaney Chassaing, Leonard B. Bacharier, Tonya Greene, Nienchun Wu, Daniel A. Searing, Edward T. Naureckas, Lilian Cadet, Jason E. Lang, Laura Bertrand, Weijiang Shen, Robert A. Wise, April Thurman, Janet Hutchins, Andrea Lears, Amber Martineau, John S. Sundy, Nancy Prusakowski, Christine A. Sorkness, Kaharu Sumino, Nina Phillips, Andreas Schmid, Flavia C.L. Hoyte, Silvia Lopez, Marie C. Sandi, Cristine E. Berry, Edward B. Mougey, Gwen Leatherman, Scott H. Sicherer, Lisa Monchil, Lucius Robinson, Dima Ezmigna, Gang Zheng, Paula J. Puntenney, Joan Reibman, V. Susan Robertson, Lisa Webber, Nicholas R. Anthonisen, Blanca A. Lopez, Michael F. Land, Kristina Rivera, Jessica Ghidorzi, Denise Thompson-Batt, Christian Bime, Brian P. Vickery, Xavier Soler, Marilyn Scharbach, Agnes Banquet, Johana Arana, Richard S. Tejedor, Suzanna Roettger, Jonathan P. Parsons, Ben Xu, Ankoor S. Shah, Denise Jaggers, Thomas Lahiri, Eliana S. Mendes, Lucy Wang, Eveline Y. Wu, David Cosmar, Gary I. Salzman, Elizabeth De La Riva-Velasco, Alicia Newcomer, John G. Mastronarde, Elizabeth A. Sugar, Razan Yasin, Mary A. Nevin, Fernando D. Martinez, Anne S Casper, Melissa M. Scheuerman, William J. Calhoun, Jesus A. Wences, James N. Moy, Virginia S. Taggart, Nicola A. Hanania, Anne E. Dixon, Asem Abdeljalil, William C. Bailey, Jessica Williams, Monroe J. King, Sarah M. Croker, Kenneth S. Knox, Mary Warde, Rubin I. Cohen, Sankaran Krishnan, Mario Castro, Newel Bryce-Robinson, Karen Carapetyan, Christine Y. Wei, Roni Grad, Stephen C. Lazarus, Nancy Busk, Patti Haney, Richard F. Lockey, Lewis J. Smith, Michael Campos, Jaime Tarsi, Wayne J. Morgan, James L. Goodwin, Norman H. Edelman, Charles G. Irvin, Noopur Singh, Janet T. Holbrook, Johnson Ukken, David A. Kaminsky, Ravi Kalhan, Kyle I. Happel, Joe Ramsdell, Mustafa A. Atik, Nancy Archer, Raymond G. Slavin, Maria Teresa Santiago, Paul Ferguson, Virginia Zagaja, Rachael A. Compton, Joseph Santiago, Katherine Chee, Brenda M. Patterson, Ramona Ramdeo, Monica T. Varela, Joseph Boyer, Allen J. Dozor, Catherine M Foss, Robert Smith, Michael Busk, Maureen Dreyfus, Marie Daniel, Sobharani Rayapudi, Shirley McCullough, Jenny Hixon, Stephen Wasserman, Holly Currier, Andrea Paco, Tara M. Formisano, Nadav Traeger, Ingrid Gherson, Thomas Matthews, Subhadra Siegel, Michelle Freemer, J.N. Saams, Rosemary Weese, Alexis L Rea, Y. Cathy Kim, Michelle M. Cloutier, Deborah Nowakowski, Kristin W. Wavell, Dennis Pyszczynski, Kathryn V. Blake, Peter J. Kahrilas, Marianna Sockrider, Rohit K. Katial, Mark A. Brown, Suzette T. Gjonaj, Zenobia Gonsalves, Arleen Antoine, Lynn B. Gerald, Emily DiMango, Linda Rogers, Debra Amend-Libercci, Abbi Brees, Deanna Seymour, Abid Bhat, John J. Lima, Stephanie Allen, Diana B. Lowenthal, Katie Kinninger, Rebecca McCrery, Janice Drake, Cori L. Daines, Charlene Levine, Elizabeth K. Fiorino, Monica M. Vasquez, Terri Montgomery, Donna Wolf, Trisha Larson

Publikováno v: JAMA. 313(20)

Importance Soy isoflavone supplements are used to treat several chronic diseases, although the data supporting their use are limited. Some data suggest that supplementation with soy isoflavone may be an effective treatment for patients with poor asth

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https://pubmed.ncbi.nlm.nih.gov/26010632