Down syndrome is associated with altered frequency and functioning of tracheal multiciliated cells, and response to influenza virus infection.

Autor: Thomas SN; Department of Bioengineering, University of Colorado Denver, Aurora, CO 80045, USA., Niemeyer BF; Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA., Jimenez-Valdes RJ; Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA., Kaiser AJ; Department of Bioengineering, University of Colorado Denver, Aurora, CO 80045, USA., Espinosa JM; Linda Crnic Institute for Down Syndrome, University of Colorado, Anschutz Medical Campus, Aurora, CO 80045, USA.; Department of Pharmacology, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA., Sullivan KD; Linda Crnic Institute for Down Syndrome, University of Colorado, Anschutz Medical Campus, Aurora, CO 80045, USA.; Department of Pediatrics, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA., Goodspeed A; Department of Pharmacology, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.; University of Colorado Comprehensive Cancer Center, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA., Costello JC; Linda Crnic Institute for Down Syndrome, University of Colorado, Anschutz Medical Campus, Aurora, CO 80045, USA.; Department of Pharmacology, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.; University of Colorado Comprehensive Cancer Center, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA., Alder JK; Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA., Cañas-Arranz R; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., García-Sastre A; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; Department of Medicine, Division of Infectious Diseases, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; Global Health and Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; The Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; Department of Pathology, Molecular and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Benam KH; Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA.; Linda Crnic Institute for Down Syndrome, University of Colorado, Anschutz Medical Campus, Aurora, CO 80045, USA.; Department of Bioengineering, University of Pittsburgh, Pittsburgh, PA 15219, USA.; Vascular Medicine Institute, University of Pittsburgh, Pittsburgh, PA 15213, USA.

Publikováno v: IScience [iScience] 2023 Jul 14; Vol. 26 (8), pp. 107361. Date of Electronic Publication: 2023 Jul 14 (Print Publication: 2023).

Untapping host-targeting cross-protective efficacy of anticoagulants against SARS-CoV-2.

Autor: Niemeyer BF; Division of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA., Benam KH; Division of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA; Department of Bioengineering, University of Pittsburgh, Pittsburgh, PA 15219, USA; Vascular Medicine Institute, University of Pittsburgh, Pittsburgh, PA 15213, USA. Electronic address: benamk@pitt.edu.

Publikováno v: Pharmacology & therapeutics [Pharmacol Ther] 2022 May; Vol. 233, pp. 108027. Date of Electronic Publication: 2021 Oct 28.

The gammaherpesvirus 68 viral cyclin facilitates expression of LANA.

Autor: Niemeyer BF; Immunology and Microbiology Department, University of Colorado Denver School of Medicine, Aurora, Colorado, United States of America., Sanford B; Department of Pediatrics, University of Colorado School of Medicine, Aurora, Colorado, United States of America., Gibson JE; Department of Pediatrics, University of Colorado School of Medicine, Aurora, Colorado, United States of America., Berger JN; Immunology and Microbiology Department, University of Colorado Denver School of Medicine, Aurora, Colorado, United States of America., Oko LM; Immunology and Microbiology Department, University of Colorado Denver School of Medicine, Aurora, Colorado, United States of America., Medina E; Immunology and Microbiology Department, University of Colorado Denver School of Medicine, Aurora, Colorado, United States of America., Clambey ET; Department of Anesthesiology, University of Colorado Anschutz Medical Campus, Aurora, Colorado, United States of America., van Dyk LF; Immunology and Microbiology Department, University of Colorado Denver School of Medicine, Aurora, Colorado, United States of America.

Publikováno v: PLoS pathogens [PLoS Pathog] 2021 Nov 15; Vol. 17 (11), pp. e1010019. Date of Electronic Publication: 2021 Nov 15 (Print Publication: 2021).

Advanced Microengineered Lung Models for Translational Drug Discovery.

Autor: Niemeyer BF; 1 Division of Pulmonary Sciences and Critical Care Medicine, Department of Medicine, University of Colorado, Anschutz Medical Campus, Aurora, CO, USA., Zhao P; 1 Division of Pulmonary Sciences and Critical Care Medicine, Department of Medicine, University of Colorado, Anschutz Medical Campus, Aurora, CO, USA., Tuder RM; 1 Division of Pulmonary Sciences and Critical Care Medicine, Department of Medicine, University of Colorado, Anschutz Medical Campus, Aurora, CO, USA., Benam KH; 1 Division of Pulmonary Sciences and Critical Care Medicine, Department of Medicine, University of Colorado, Anschutz Medical Campus, Aurora, CO, USA.; 2 Department of Bioengineering, University of Colorado Denver, Aurora, CO, USA.

Publikováno v: SLAS discovery : advancing life sciences R & D [SLAS Discov] 2018 Sep; Vol. 23 (8), pp. 777-789. Date of Electronic Publication: 2018 Feb 15.

A Conserved Gammaherpesvirus Cyclin Specifically Bypasses Host p18(INK4c) To Promote Reactivation from Latency.

Autor: Williams LM; Immunology and Microbiology Department, University of Colorado Denver School of Medicine, Aurora, Colorado, USA., Niemeyer BF; Immunology and Microbiology Department, University of Colorado Denver School of Medicine, Aurora, Colorado, USA., Franklin DS; Biochemistry Department, Tulane University, New Orleans, Louisiana, USA., Clambey ET; Anesthesiology Department, University of Colorado Denver School of Medicine, Aurora, Colorado, USA., van Dyk LF; Immunology and Microbiology Department, University of Colorado Denver School of Medicine, Aurora, Colorado, USA linda.vandyk@ucdenver.edu.

Publikováno v: Journal of virology [J Virol] 2015 Nov; Vol. 89 (21), pp. 10821-31. Date of Electronic Publication: 2015 Aug 19.