Target lysis by cholesterol extraction is a rate limiting step in the resolution of phagolysosomes

Autor: Dante Barreda, Sergio Grinstein, Spencer A. Freeman

Publikováno v: European Journal of Cell Biology, Vol 103, Iss 1, Pp 151382- (2024)

The ongoing phagocytic activity of macrophages necessitates an extraordinary capacity to digest and resolve incoming material. While the initial steps leading to the formation of a terminal phagolysosome are well studied, much less is known about the

Externí odkaz: https://doaj.org/article/f07f20a17f20420595cd112d07adbcb7

Identification of Niemann-Pick C1 protein as a potential novel SARS-CoV-2 intracellular target

Autor: Urtzi Garaigorta, Isabel García-Dorival, Carmen Gil, Ana del Puerto, Nuria E. Campillo, Pablo Gastaminza, Covadonga Alonso, Miguel Ángel Cuesta-Geijo, Ana Martínez, Inmaculada Galindo, Lucía Barrado-Gil, Jesús Urquiza

Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
instname
ANTIVIRAL RESEARCH
Digital.CSIC: Repositorio Institucional del CSIC
Consejo Superior de Investigaciones Científicas (CSIC)
Antiviral Research

10 p.-4 fig.
Niemann-Pick type C1 (NPC1) receptor is an endosomal membrane protein that regulates intracellular cholesterol traffic. This protein has been shown to play an important role for several viruses. It has been reported that SARS-CoV-2

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c227588c170d1d4987230aac291abb7
http://hdl.handle.net/10261/248905

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.