An overview of the role of Niemann-pick C1 (NPC1) in viral infections and inhibition of viral infections through NPC1 inhibitor.

Autor: Ahmad, Irfan¹ (AUTHOR), Fatemi, Seyede Narges² (AUTHOR), Ghaheri, Mohammad³ (AUTHOR), Rezvani, Ali⁴ (AUTHOR), Khezri, Dorsa Azizi⁵ (AUTHOR), Natami, Mohammad⁶ (AUTHOR), Yasamineh, Saman⁷ (AUTHOR) Yassaman124@gmail.com, Gholizadeh, Omid⁷ (AUTHOR) ogholizade1374@gmail.com, Bahmanyar, Zahra⁸ (AUTHOR) zhra.bmnyr97@gmail.com

Publikováno v: Cell Communication & Signaling. 12/14/2023, Vol. 21 Issue 1, p1-16. 16p.

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Niemann-Pick C1 protein regulates platelet membrane-associated calcium ion signaling in thrombo-occlusive diseases in mice.

Autor: Manke MC; DFG Heisenberg Group Thrombocardiology; Department of Cardiology, Angiology and Cardiovascular Medicine, University of Tübingen, Germany., Roslan A; Department of Pharmacology, Toxicology and Clinical Pharmacy, University of Tübingen, Germany., Walker B; DFG Heisenberg Group Thrombocardiology., Münzer P; DFG Heisenberg Group Thrombocardiology; Department of Cardiology, Angiology and Cardiovascular Medicine, University of Tübingen, Germany., Kollotzek F; DFG Heisenberg Group Thrombocardiology; Department of Cardiology, Angiology and Cardiovascular Medicine, University of Tübingen, Germany., Peng B; Leibniz-Institut für Analytische Wissenschaften-ISAS, Dortmund, Germany; Division of Rheumatology, Department of Medicine Solna, Karolinska Institute, Karolinska University Hospital, Stockholm, Sweden., Mencl S; Department of Neurology and Center for Translational Neuro- and Behavioral Sciences (C-TNBS), University Hospital Essen, University of Duisburg-Essen, Essen, Germany., Coman C; Department of Analytical Chemistry, University of Vienna, Austria., Szepanowski RD; Department of Neurology and Center for Translational Neuro- and Behavioral Sciences (C-TNBS), University Hospital Essen, University of Duisburg-Essen, Essen, Germany., Schulze H; Institute of Experimental Biomedicine, University Hospital Würzburg, Germany., Lieberman AP; Department of Pathology, University of Michigan Medical School, USA., Lang F; Department of Physiology, University of Tübingen, Germany., Gawaz M; DFG Heisenberg Group Thrombocardiology., Kleinschnitz C; Department of Neurology and Center for Translational Neuro- and Behavioral Sciences (C-TNBS), University Hospital Essen, University of Duisburg-Essen, Essen, Germany., Lukowski R; Department of Pharmacology, Toxicology and Clinical Pharmacy, University of Tübingen, Germany., Ahrends R; Leibniz-Institut für Analytische Wissenschaften-ISAS, Dortmund, Germany; Department of Analytical Chemistry, University of Vienna, Austria., Bobe R; HITh, UMR_S1176, INSERM, Université Paris-Saclay, France., Borst O; DFG Heisenberg Group Thrombocardiology; Department of Cardiology, Angiology and Cardiovascular Medicine, University of Tübingen, Germany. Electronic address: oliver.borst@med.uni-tuebingen.de.

Publikováno v: Journal of thrombosis and haemostasis : JTH [J Thromb Haemost] 2023 Jul; Vol. 21 (7), pp. 1957-1966. Date of Electronic Publication: 2023 Apr 11.

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Purification and structure of luminal domain C of human Niemann-Pick C1 protein.

Autor: Odongo L; Center for Membrane and Cell Physiology, University of Virginia, Charlottesville, VA 22908, USA., Zadrozny KK; Center for Membrane and Cell Physiology, University of Virginia, Charlottesville, VA 22908, USA., Diehl WE; Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, MA 01605, USA., Luban J; Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, MA 01605, USA., White JM; Center for Membrane and Cell Physiology, University of Virginia, Charlottesville, VA 22908, USA., Ganser-Pornillos BK; Center for Membrane and Cell Physiology, University of Virginia, Charlottesville, VA 22908, USA., Tamm LK; Center for Membrane and Cell Physiology, University of Virginia, Charlottesville, VA 22908, USA., Pornillos O; Center for Membrane and Cell Physiology, University of Virginia, Charlottesville, VA 22908, USA.

Publikováno v: Acta crystallographica. Section F, Structural biology communications [Acta Crystallogr F Struct Biol Commun] 2023 Feb 01; Vol. 79 (Pt 2), pp. 45-50. Date of Electronic Publication: 2023 Feb 02.