Impact of gluten intake on clinical outcomes in patients with chronic inflammatory diseases initiating biologics: Secondary analysis of the prospective multicentre BELIEVE cohort study.

Autor: Gregersen L; Molecular Diagnostics and Clinical Research Unit, University Hospital of Southern Denmark, Aabenraa, Denmark.; The Faculty of Health Sciences, Institute of Regional Health Research, University of Southern Denmark, Odense, Denmark., Jessen PD; Molecular Diagnostics and Clinical Research Unit, University Hospital of Southern Denmark, Aabenraa, Denmark.; The Faculty of Health Sciences, Institute of Regional Health Research, University of Southern Denmark, Odense, Denmark., Lund HW; Molecular Diagnostics and Clinical Research Unit, University Hospital of Southern Denmark, Aabenraa, Denmark.; The Faculty of Health Sciences, Institute of Regional Health Research, University of Southern Denmark, Odense, Denmark., Overgaard SH; Molecular Diagnostics and Clinical Research Unit, University Hospital of Southern Denmark, Aabenraa, Denmark.; The Faculty of Health Sciences, Institute of Regional Health Research, University of Southern Denmark, Odense, Denmark., Hikmat Z; Molecular Diagnostics and Clinical Research Unit, University Hospital of Southern Denmark, Aabenraa, Denmark.; The Faculty of Health Sciences, Institute of Regional Health Research, University of Southern Denmark, Odense, Denmark., Ellingsen T; Research Unit of Rheumatology, Department of Clinical Research, University of Southern Denmark, Odense University Hospital, Odense, Denmark., Kjeldsen J; Research Unit of Gastroenterology, Department of Clinical Research, University of Southern Denmark, Odense University Hospital, Odense, Denmark., Pedersen AK; Department of Clinical Research, University Hospital of Southern Denmark, Aabenraa, Denmark.; Open Patient Data Exploration Network (OPEN), Odense, Denmark., Petersen SR; Department of Clinical Research, University Hospital of Southern Denmark, Aabenraa, Denmark., Jawhara M; Section of Upper Benign and Hernia Surgery (G3), Department of Surgery, Odense University Hospital, Svendborg, Denmark., Nexøe AB; The Faculty of Health Sciences, Institute of Regional Health Research, University of Southern Denmark, Odense, Denmark., Bygum A; Research Unit of Human Genetics, Department of Clinical Research, University of Southern Denmark, Odense University Hospital, Odense, Denmark., Hvas CL; Institute of Clinical Medicine, Aarhus University, Aarhus, Denmark.; Department of Hepatology and Gastroenterology, Aarhus University Hospital, Aarhus, Denmark., Dahlerup JF; Department of Hepatology and Gastroenterology, Aarhus University Hospital, Aarhus, Denmark.; The Abdominal Center, Medical Section, Bispebjerg University Hospital, Copenhagen, Denmark., Bergenheim FO; The Abdominal Center, Medical Section, Bispebjerg University Hospital, Copenhagen, Denmark., Glerup H; University Research Clinic for Innovative Patient Pathways, Silkeborg Regional Hospital, Silkeborg, Denmark., Henriksen RH; University Research Clinic for Innovative Patient Pathways, Silkeborg Regional Hospital, Silkeborg, Denmark., Guldmann T; University Research Clinic for Innovative Patient Pathways, Silkeborg Regional Hospital, Silkeborg, Denmark., Hvid L; Department of Dermatology and Allergy Centre, Odense University Hospital, Odense, Denmark., Brodersen J; The Faculty of Health Sciences, Institute of Regional Health Research, University of Southern Denmark, Odense, Denmark.; Department of Internal Medicine-Gastroenterology, Esbjerg & Grindsted Hospital, University Hospital of Southern Denmark, Esbjerg, Denmark., Munk HL; Department of Rheumatology, Odense University Hospital, Odense, Denmark.; Center for Rheumatology and Spine Diseases, Rigshospitalet, Copenhagen, Denmark., Pedersen N; Department of Gastroenterology, Slagelse Regional Hospital, Slagelse, Denmark., Saboori S; Department of Gastroenterology, Slagelse Regional Hospital, Slagelse, Denmark., Nielsen OH; Department of Gastroenterology, Herlev Hospital, Herlev, Denmark., Heitmann BL; Research Unit for Dietary Studies, The Parker Institute, Bispebjerg and Frederiksberg Hospital, Copenhagen, Denmark., Haldorsson TI; Molecular Diagnostics and Clinical Research Unit, University Hospital of Southern Denmark, Aabenraa, Denmark.; Faculty of Food Science and Nutrition, University of Iceland, Reykjavik, Iceland., Christensen R; Research Unit of Rheumatology, Department of Clinical Research, University of Southern Denmark, Odense University Hospital, Odense, Denmark.; Section for Biostatistics and Evidence-Based Research, The Parker Institute, Bispebjerg and Frederiksberg Hospital, Copenhagen, Denmark., Andersen V; Open Patient Data Exploration Network (OPEN), Odense, Denmark.; Institute of Molecular Medicine, University of Southern Denmark, Odense, Denmark.

Publikováno v: Scandinavian journal of immunology [Scand J Immunol] 2024 Oct 02, pp. e13409. Date of Electronic Publication: 2024 Oct 02.

Microfibrillar-associated protein 4 as a predictive biomarker of treatment response in patients with chronic inflammatory diseases initiating biologics: secondary analyses based on the prospective BELIEVE cohort study.

Autor: Sofíudóttir BK; Department of Rheumatology, Odense University Hospital, Odense, Denmark. bks@rsyd.dk.; Research Unit of Rheumatology, Department of Clinical Research, University of Southern Denmark, Odense University Hospital, Odense, Denmark. bks@rsyd.dk.; Section for Biostatistics and Evidence-Based Research, the Parker Institute, Bispebjerg and Frederiksberg Hospital, Copenhagen, Denmark. bks@rsyd.dk., Munk HL; Department of Rheumatology, Odense University Hospital, Odense, Denmark.; Center for Rheumatology and Spine Diseases, Rigshospitalet, Glostrup, Denmark., Christensen R; Research Unit of Rheumatology, Department of Clinical Research, University of Southern Denmark, Odense University Hospital, Odense, Denmark.; Section for Biostatistics and Evidence-Based Research, the Parker Institute, Bispebjerg and Frederiksberg Hospital, Copenhagen, Denmark.; Cochrane Denmark & Centre for Evidence-Based Medicine Odense (CEBMO), Department of Clinical Research, University of Southern Denmark, Odense, Denmark., Möller S; OPEN - Open Patient Data Explorative Network, Odense University Hospital, Odense, Denmark.; Department of Clinical Research, University of Southern Denmark, Odense, Denmark., Overgaard SH; Section for Biostatistics and Evidence-Based Research, the Parker Institute, Bispebjerg and Frederiksberg Hospital, Copenhagen, Denmark.; Internal Medicine Research, Unit University Hospital of Southern Denmark, Aabenraa, Denmark.; Department of Regional Health Research, University of Southern, Odense, Denmark., Sorensen GL; Department of Inflammation Research, Institute of Molecular Medicine, University of Southern Denmark, Odense, Denmark., Møllegaard KM; Internal Medicine Research, Unit University Hospital of Southern Denmark, Aabenraa, Denmark.; Department of Regional Health Research, University of Southern, Odense, Denmark., Pingel J; Internal Medicine Research, Unit University Hospital of Southern Denmark, Aabenraa, Denmark.; Department of Regional Health Research, University of Southern, Odense, Denmark., Nexøe AB; Department of Inflammation Research, Institute of Molecular Medicine, University of Southern Denmark, Odense, Denmark.; Department of Medical Gastroenterology, Odense University Hospital, Odense, Denmark., Glerup H; University Research Clinic for Innovative Patient Pathways, Silkeborg Regional Hospital, Silkeborg, Denmark., Guldmann T; University Research Clinic for Innovative Patient Pathways, Silkeborg Regional Hospital, Silkeborg, Denmark., Pedersen N; Department of Gastroenterology, Slagelse Hospital, Slagelse, Denmark., Dahlerup JF; Department of Hepatology and Gastroenterology, Aarhus University Hospital, Aarhus, Denmark., Hvas CL; Department of Hepatology and Gastroenterology, Aarhus University Hospital, Aarhus, Denmark., Andersen KW; Department of Regional Health Research, University of Southern, Odense, Denmark.; Department of Surgery, University Hospital of Southern Denmark, Aabenraa, Denmark., Jawhara M; Department of Surgery, University Hospital of Southern Denmark, Aabenraa, Denmark., Nielsen OH; Department of Gastroenterology, Herlev Hospital, University of Copenhagen, Herlev, Denmark., Bergenheim FO; The Abdominal Center, Medical Section, Bispebjerg and Frederiksberg University Hospital, Copenhagen, Denmark., Bygum A; Department of Clinical Research, University of Southern Denmark, Odense, Denmark., Davidsen JR; Department of Clinical Research, University of Southern Denmark, Odense, Denmark.; Department of Respiratory Medicine, Odense University Hospital, Odense, Denmark., Sørensen SB; Internal Medicine Research, Unit University Hospital of Southern Denmark, Aabenraa, Denmark.; Department of Regional Health Research, University of Southern, Odense, Denmark.; Department of Inflammation Research, Institute of Molecular Medicine, University of Southern Denmark, Odense, Denmark., Brodersen JB; Department of Regional Health Research, University of Southern, Odense, Denmark.; Department of Gastroenterology, Esbjerg and Grindsted Hospital - University Hospital of Southern Denmark, Esbjerg, Denmark., Kjeldsen J; Department of Medical Gastroenterology, Odense University Hospital, Odense, Denmark.; Research Unit of Medical Gastroenterology, Department of Clinical Research, University of Southern Denmark, Odense, Denmark., Andersen V; Internal Medicine Research, Unit University Hospital of Southern Denmark, Aabenraa, Denmark.; Department of Regional Health Research, University of Southern, Odense, Denmark.; Department of Inflammation Research, Institute of Molecular Medicine, University of Southern Denmark, Odense, Denmark., Ellingsen T; Department of Rheumatology, Odense University Hospital, Odense, Denmark.; Research Unit of Rheumatology, Department of Clinical Research, University of Southern Denmark, Odense University Hospital, Odense, Denmark.; Department of Clinical Research, University of Southern Denmark, Odense, Denmark.

Publikováno v: Rheumatology international [Rheumatol Int] 2024 Oct 28. Date of Electronic Publication: 2024 Oct 28.

In Severe Inflammatory Bowel Disease, the Onset of Effectiveness of Biologics and Small Molecules Depends More on the Medication Than on the Diagnosis.

Autor: Attauabi M; Department of Gastroenterology and Hepatology, Copenhagen University Hospital - Herlev and Gentofte, Herlev, Denmark.; Gastrounit, Medical Section, Copenhagen University Hospital - Amager and Hvidovre, Hvidovre, Denmark.; Copenhagen Center for Inflammatory Bowel Disease in Children, Adolescents, and Adults, Hvidovre Hospital, Hvidovre, Denmark.; Faculty of Health and Medical Sciences, Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark., Burisch J; Gastrounit, Medical Section, Copenhagen University Hospital - Amager and Hvidovre, Hvidovre, Denmark.; Copenhagen Center for Inflammatory Bowel Disease in Children, Adolescents, and Adults, Hvidovre Hospital, Hvidovre, Denmark.; Faculty of Health and Medical Sciences, Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark., Nielsen OH; Department of Gastroenterology and Hepatology, Copenhagen University Hospital - Herlev and Gentofte, Herlev, Denmark.; Faculty of Health and Medical Sciences, Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark., Seidelin JB; Department of Gastroenterology and Hepatology, Copenhagen University Hospital - Herlev and Gentofte, Herlev, Denmark.; Faculty of Health and Medical Sciences, Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.

Publikováno v: Inflammatory bowel diseases [Inflamm Bowel Dis] 2024 Oct 03; Vol. 30 (10), pp. 1931-1932.

JAK/STAT signaling promotes the emergence of unique cell states in ulcerative colitis.

Autor: Maciag G; Novo Nordisk Foundation Center for Stem Cell Medicine (reNEW), Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen N, Denmark., Hansen SL; Novo Nordisk Foundation Center for Stem Cell Medicine (reNEW), Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen N, Denmark., Krizic K; Novo Nordisk Foundation Center for Stem Cell Medicine (reNEW), Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen N, Denmark., Kellermann L; Department of Gastroenterology, Herlev Hospital, University of Copenhagen, 2730 Herlev, Denmark., Inventor Zøylner MJ; Novo Nordisk Foundation Center for Stem Cell Medicine (reNEW), Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen N, Denmark., Ulyanchenko S; Novo Nordisk Foundation Center for Stem Cell Medicine (reNEW), Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen N, Denmark., Maimets M; Novo Nordisk Foundation Center for Stem Cell Medicine (reNEW), Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen N, Denmark., Baattrup AM; Novo Nordisk Foundation Center for Stem Cell Medicine (reNEW), Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen N, Denmark., Riis LB; Department of Pathology, Herlev Hospital, University of Copenhagen, 2730 Herlev, Denmark., Khodosevich K; Biotech Research and Innovation Centre, University of Copenhagen, 2200 Copenhagen N, Denmark., Sato T; Department of Organoid Medicine, Keio University School of Medicine, Tokyo, Japan; Department of Gastroenterology, Keio University School of Medicine, Tokyo, Japan., Bressan RB; Novo Nordisk Foundation Center for Stem Cell Medicine (reNEW), Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen N, Denmark. Electronic address: raul.bressan@sund.ku.dk., Nielsen OH; Department of Gastroenterology, Herlev Hospital, University of Copenhagen, 2730 Herlev, Denmark. Electronic address: ohn@dadlnet.dk., Jensen KB; Novo Nordisk Foundation Center for Stem Cell Medicine (reNEW), Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen N, Denmark; Biotech Research and Innovation Centre, University of Copenhagen, 2200 Copenhagen N, Denmark. Electronic address: kim.jensen@sund.ku.dk.

Publikováno v: Stem cell reports [Stem Cell Reports] 2024 Aug 13; Vol. 19 (8), pp. 1172-1188. Date of Electronic Publication: 2024 Jul 18.

Organoids as regenerative medicine for inflammatory bowel disease.

Autor: Hammerhøj A; Department of Gastroenterology, Herlev Hospital, University of Copenhagen, Herlev, Denmark., Chakravarti D; Department of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Sato T; Department of Organoid Medicine, Keio University School of Medicine, Tokyo, Japan., Jensen KB; Novo Nordisk Foundation Center for Stem Cell Medicine (reNEW), Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Nielsen OH; Department of Gastroenterology, Herlev Hospital, University of Copenhagen, Herlev, Denmark.

Publikováno v: IScience [iScience] 2024 May 27; Vol. 27 (6), pp. 110118. Date of Electronic Publication: 2024 May 27 (Print Publication: 2024).