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Autor:
Riggi N Knoechel B Gillespie S Rheinbay E Boulay G Suvà ML, Nielsen GP Stamenkovic I Aryee MJ Bernstein BE Rivera MN
Publikováno v:
Cancer Cell
The aberrant transcription factor EWS FLI1 drives Ewing sarcoma but its molecular function is not completely understood. We find that EWS FLI1 reprograms gene regulatory circuits in Ewing sarcoma by directly inducing or repressing enhancers. At GGAA