Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Niels Wedemeyer"'
Autor:
Elke Pascher, Erhard Severin, U. Hacker-Klom, Normann Willich, Burkhard Greve, Niels Wedemeyer, Joachim Kienast, Gerda Silling, Wolfgang Göhde
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 64:242-250
Purpose: An escalation in standard irradiation dose ensuring improved local tumor control is estimated, but this strategy would require the exclusion of the most sensitive individuals from treatment. Therefore, fast and reliable assays for prediction
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69c3b8771e42646d5e8868cb82422b89
https://doi.org/10.1016/j.ijrobp.2005.06.020
https://doi.org/10.1016/j.ijrobp.2005.06.020
Autor:
Klaus-Dieter Greif, Erhard Severin, H. J. Brede, W. Köhnlein, D. Schlegel, Wolfgang Göhde, Niels Wedemeyer, D. Uthe
Publikováno v:
International Journal of Radiation Biology. 79:911-918
The shape of the dose-effect curve for neutrons, i.e. the question as to whether the curve is linear or supralinear in the low-dose region, is still not clear. Therefore, the mutagenic effect of very low doses of low-energy neutrons was determined.Hu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad9cfcb2556bad7e2c90505278a9f44f
https://doi.org/10.1080/09553000310001621419
https://doi.org/10.1080/09553000310001621419
Publikováno v:
Clinical Chemistry. 48:1398-1405
Background: Competitive PCR of reverse transcribed mRNA sequences is used to quantify transcripts, but the usual approaches are labor-intensive and time-consuming. We describe the non-gel-based quantification of competitive reverse transcription (RT)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bf3bf7a969a72f1dbb67b7545e91c49
https://doi.org/10.1093/clinchem/48.9.1398
https://doi.org/10.1093/clinchem/48.9.1398
Autor:
Erhard Severin, Burkhard Greve, U. Hacker-Klom, Niels Wedemeyer, Wolfgang Köhnlein, Wolfgang Göhde, Daniela Uthe, Dagmar Denklau, Thomas Pötter
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 473:73-84
Determination of the genotoxic effects of ionizing radiation, especially at low-doses, is of great importance for risk assessment, e.g. in radiological diagnostics. The human-hamster hybrid A L cell line has been shown previously to be a well-suited
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c402e45ec11a1b9099e060be86ee2bfb
https://doi.org/10.1016/s0027-5107(00)00137-8
https://doi.org/10.1016/s0027-5107(00)00137-8
Autor:
Dirk Korthaus, Cora S. Thiel, Harald Jockusch, Karin Resch, Thomas Schmitt-John, Melanie Ronsiek, Niels Wedemeyer, Kristin Baer, Andreas Lengeling
Publikováno v:
Mammalian Genome. 9:893-898
Human Chr 2p13-14 and homologous regions on mouse Chrs 6 and 11 have been subjects of previous studies because they comprise the loci for several neuromuscular diseases. Here we report on high-resolution mapping of 55 STS and EST loci on human Chr 2p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::006c3ead05b96f57e2111f1fd6a1faa4
https://doi.org/10.1007/s003359900890
https://doi.org/10.1007/s003359900890
Autor:
Erich E. Wanker, Renate Hasenbank, Eberhard Scherzinger, Holger Eickhoff, Hans Lehrach, Niels Wedemeyer, Stephanie Wälter, Annie Sittler, Gillian P. Bates
Publikováno v:
Molecular Cell. 2:427-436
The mechanism by which aggregated polyglns cause the selective neurodegeneration in Huntington's disease (HD) is unknown. Here, we show that the SH3GL3 protein, which is preferentially expressed in brain and testis, selectively interacts with the HD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34e24ff6c5216bb261eab80740d7be8c
https://doi.org/10.1016/s1097-2765(00)80142-2
https://doi.org/10.1016/s1097-2765(00)80142-2
Publikováno v:
Genomics. 46:313-315
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::741272faddf4bb4109c57958e212a055
https://doi.org/10.1006/geno.1997.5027
https://doi.org/10.1006/geno.1997.5027
Publikováno v:
Mutation research. 476(1-2)
Using repetitive elements as probes, genomic DNA fingerprints of four randomly selected yeast artificial chromosome (YAC) clones (two human and two mouse-derived YAC) were analyzed to determine the mutation level following X-ray exposure. Because the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e926663a3f6f7c55de76e31fff7fe7e
https://pubmed.ncbi.nlm.nih.gov/11336981
https://pubmed.ncbi.nlm.nih.gov/11336981
Publikováno v:
Radiation research. 154(2)
The incidence of skin cancer is increasing in epidemic proportion. Although solar UV radiation is known to be the major risk factor, much information is lacking about the molecular mechanisms leading to skin cancer. To gain a deeper insight into thes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f7e6046f764ca289879082c0cc19ae2
https://pubmed.ncbi.nlm.nih.gov/10931686
https://pubmed.ncbi.nlm.nih.gov/10931686
Publikováno v:
Clinical chemistry. 46(8 Pt 1)
Background: Reverse transcription-PCR (RT-PCR) is a powerful tool in clinical diagnostics for analyzing even small amounts of RNA, but sensitive assays for quantifying the amplification products are time-consuming or expensive. Here we describe a nov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba420a24d5dccd37cb697fc03d5aae75
https://pubmed.ncbi.nlm.nih.gov/10926883
https://pubmed.ncbi.nlm.nih.gov/10926883