Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Niels W. C. J. Van de Donk"'
Autor:
Paula Rodriguez-Otero, Niels W. C. J. van de Donk, Kodandaram Pillarisetti, Ingrid Cornax, Deeksha Vishwamitra, Kathleen Gray, Brandi Hilder, Jaszianne Tolbert, Thomas Renaud, Tara Masterson, Christoph Heuck, Colleen Kane, Raluca Verona, Philippe Moreau, Nizar Bahlis, Ajai Chari
Publikováno v:
Blood Cancer Journal, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Multiple myeloma is a genetically complex and heterogenous malignancy with a 5-year survival rate of approximately 60%. Despite advances in therapy, patients experience cycles of remission and relapse, with each successive line of therapy as
Externí odkaz:
https://doaj.org/article/3ef6305f5c894c229cdfe5cd8505447b
Autor:
Paula Rodriguez-Otero, Niels W. C. J. van de Donk, Kodandaram Pillarisetti, Ingrid Cornax, Deeksha Vishwamitra, Kathleen Gray, Brandi Hilder, Jaszianne Tolbert, Thomas Renaud, Tara Masterson, Christoph Heuck, Colleen Kane, Raluca Verona, Philippe Moreau, Nizar Bahlis, Ajai Chari
Publikováno v:
Blood Cancer Journal, Vol 14, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/e057160cc1394d3d997f011a0b01b171
Autor:
Mirian Brink, Monique C. Minnema, Otto Visser, Mark-David Levin, Eduardus F. M. Ward Posthuma, Annemiek Broijl, Pieter Sonneveld, Marjolein van der Klift, Wilfried W. H. Roeloffzen, Matthijs Westerman, Cleo R. van Rooijen, Paul A. F. Geerts, Sonja Zweegman, Niels W. C. J. van de Donk, Avinash G. Dinmohamed
Publikováno v:
Blood Cancer Journal, Vol 12, Iss 3, Pp 1-4 (2022)
Externí odkaz:
https://doaj.org/article/7eef70a1e844411ea966620a09685d92
Autor:
Adam D. Cohen, Samir Parekh, Bianca D. Santomasso, Jaime Gállego Pérez-Larraya, Niels W. C. J. van de Donk, Bertrand Arnulf, Maria-Victoria Mateos, Nikoletta Lendvai, Carolyn C. Jackson, Kevin C. De Braganca, Jordan M. Schecter, Loreta Marquez, Erin Lee, Ingrid Cornax, Enrique Zudaire, Claire Li, Yunsi Olyslager, Deepu Madduri, Helen Varsos, Lida Pacaud, Muhammad Akram, Dong Geng, Andrzej Jakubowiak, Hermann Einsele, Sundar Jagannath
Publikováno v:
Blood Cancer Journal, Vol 12, Iss 2, Pp 1-9 (2022)
Abstract Chimeric antigen receptor (CAR) T-cell therapies are highly effective for multiple myeloma (MM) but their impressive efficacy is associated with treatment-related neurotoxicities in some patients. In CARTITUDE-1, 5% of patients with MM repor
Externí odkaz:
https://doaj.org/article/c52ccfe861b6431796f476020b355a8d
Autor:
Mirian Brink, Kaz Groen, Pieter Sonneveld, Monique C. Minnema, Annemiek Broijl, Avinash G. Dinmohamed, Ellen van der Spek, Mark-David Levin, Paula F. Ypma, Esther de Waal, Eduardus F. M. Ward Posthuma, Sonja Zweegman, Niels W. C. J. van de Donk
Publikováno v:
Blood Cancer Journal, Vol 11, Iss 11, Pp 1-7 (2021)
Abstract Identification of risk factors for early mortality (EM) in multiple myeloma (MM) patients may contribute to different therapeutic approaches in patients at risk for EM. This population-based study aimed to assess trends in EM and risk factor
Externí odkaz:
https://doaj.org/article/10e01658db454831b4b2e5e6af5592ee
Autor:
Stefanie Slot, Niels W. C. J. van de Donk, René H. J. Otten, Bouke J. H. Boden, Josée Zijlstra, Pieter G. H. M. Raijmakers, Sonja Zweegman
Publikováno v:
Cancer Imaging, Vol 21, Iss 1, Pp 1-13 (2021)
Abstract Background Diagnostic and treatment response criteria for the JAK2/CALR/MPL mutation-related myeloproliferative neoplasms (MPNs) are largely based on bone marrow (BM) biopsy results. However, these biopsies have several limitations, such as
Externí odkaz:
https://doaj.org/article/3e1c7c05def847efaef3a2a7281eae06
Publikováno v:
Hemato, Vol 2, Iss 1, Pp 116-130 (2021)
In the 2010s, immunotherapy revolutionized the treatment landscape of multiple myeloma. CD38-targeting antibodies were initially applied as monotherapy in end-stage patients, but are now also approved by EMA/FDA in combination with standards-of-care
Externí odkaz:
https://doaj.org/article/33c01c8ea07e4041822f5d012e1e2948
Autor:
Arwen Stikvoort, Jort van der Schans, Subhashis Sarkar, Renée Poels, Ruud Ruiter, Jyoti Naik, Huipin Yuan, Joost D. de Bruijn, Niels W. C. J. van de Donk, Sonja Zweegman, Maria Themeli, Richard Groen, Michael O’Dwyer, Tuna Mutis
Publikováno v:
HemaSphere, Vol 5, Iss 7, p e596 (2021)
Chimeric antigen receptor (CAR) T cells are highly successful in the treatment of hematologic malignancies. We recently generated affinity-optimized CD38CAR T cells, which effectively eliminate multiple myeloma (MM) cells with little or no toxicities
Externí odkaz:
https://doaj.org/article/0d632eee6293461a9238e2e2e12fa1df
Autor:
Lisa C. Holthof, Arwen Stikvoort, Hilma J. van der Horst, Anne T. Gelderloos, Renée Poels, Fengzhi Li, Richard W. J. Groen, Sonja Zweegman, Niels W. C. J. van de Donk, Michael O’Dwyer, Tuna Mutis
Publikováno v:
HemaSphere, Vol 5, Iss 5, p e561 (2021)
We have recently shown the strong negative impact of multiple myeloma (MM)-bone marrow mesenchymal stromal cell (BMMSC) interactions to several immunotherapeutic strategies including conventional T cells, chimeric antigen receptor (CAR) T cells, and
Externí odkaz:
https://doaj.org/article/58b52a303c724b53a0467fbcccf06ef7
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Externí odkaz:
https://doaj.org/article/c1c360c4a938464088c0b17b6a560494