Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Niels Vandewalle"'
Autor:
Niels Vandewalle, Nathan De Beule, Ann De Becker, Elke De Bruyne, Eline Menu, Karin Vanderkerken, Karine Breckpot, Nick Devoogdt, Kim De Veirman
Publikováno v:
Experimental Hematology & Oncology, Vol 13, Iss 1, Pp 1-20 (2024)
Abstract Until recently, treatment options for patients diagnosed with Acute Myeloid Leukemia (AML) were limited and predominantly relied on various combinations, dosages, or schedules of traditional chemotherapeutic agents. Patients with advanced ag
Externí odkaz:
https://doaj.org/article/b82af3f652d947baaa454fecce5ba893
Autor:
Yanmeng Wang, Niels Vandewalle, Kim De Veirman, Karin Vanderkerken, Eline Menu, Elke De Bruyne
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-17 (2024)
Abstract Multiple Myeloma (MM), a cancer of terminally differentiated plasma cells, is the second most prevalent hematological malignancy and is incurable due to the inevitable development of drug resistance. Intense protein synthesis is a distinctiv
Externí odkaz:
https://doaj.org/article/e5bf627c82af4b75bb7d189ce17c47ad
Autor:
Rong Fan, Hatice Satilmis, Niels Vandewalle, Emma Verheye, Elke De Bruyne, Eline Menu, Nathan De Beule, Ann De Becker, Gamze Ates, Ann Massie, Tessa Kerre, Marie Törngren, Helena Eriksson, Karin Vanderkerken, Karine Breckpot, Ken Maes, Kim De Veirman
Publikováno v:
Blood Cancer Journal, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Acute Myeloid Leukemia (AML) is a heterogeneous disease with limited treatment options and a high demand for novel targeted therapies. Since myeloid-related protein S100A9 is abundantly expressed in AML, we aimed to unravel the therapeutic i
Externí odkaz:
https://doaj.org/article/e3d2c809e45a47e385516477b86ed8c1
Autor:
Marie Törngren, Rong Fan, Eline Menu, Helena Eriksson, Karin Vanderkerken, Andrew Chantry, Hatice Satilmis, Niels Vandewalle, Emma Verheye, Philip Vlummens, Anke Maes, Catharina Muylaert, Elke De Bruyne, Holly Evans, Nathan De Beule, Dirk Hose, Ken Maes, Karine Breckpot, Kim De Veirman
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 1 (2023)
Background Immunotherapy emerged as a promising treatment option for multiple myeloma (MM) patients. However, therapeutic efficacy can be hampered by the presence of an immunosuppressive bone marrow microenvironment including myeloid cells. S100A9 wa
Externí odkaz:
https://doaj.org/article/d2125622a63f49eba73f4bc280a4cd85
Autor:
Hatice Satilmis, Emma Verheye, Philip Vlummens, Inge Oudaert, Niels Vandewalle, Rong Fan, Jennifer M Knight, Nathan De Beule, Gamze Ates, Ann Massie, Jerome Moreaux, Anke Maes, Elke De Bruyne, Karin Vanderkerken, Eline Menu, Erica K Sloan, Kim De Veirman
Publikováno v:
Vrije Universiteit Brussel
While multi-drug combinations and continuous treatment have become standard for multiple myeloma, the disease remains incurable. Repurposing drugs that are currently used for other indications could provide a novel approach to improve the therapeutic
Autor:
Rong Fan, Hatice Satilmis, Niels Vandewalle, Emma Verheye, Philip Vlummens, Anke Maes, Catharina Muylaert, Elke De Bruyne, Eline Menu, Holly Evans, Andrew Chantry, Nathan De Beule, Dirk Hose, Marie Törngren, Helena Eriksson, Karin Vanderkerken, Ken Maes, Karine Breckpot, Kim De Veirman
Publikováno v:
Journal for ImmunoTherapy of Cancer. 11:e005319
BackgroundImmunotherapy emerged as a promising treatment option for multiple myeloma (MM) patients. However, therapeutic efficacy can be hampered by the presence of an immunosuppressive bone marrow microenvironment including myeloid cells. S100A9 was
Autor:
Marie Törngren, Helena Eriksson, Kim De Veirman, Hatice Satilmis, Karine Breckpot, Elke De Bruyne, Holly Evans, Andrew D Chantry, Rong Fan, Eline Menu, Ken Maes, Karin Vanderkerken, Niels Vandewalle
Publikováno v:
Vrije Universiteit Brussel
Introduction Immunotherapy has revolutionized cancer treatment and significantly affected the management of Multiple Myeloma (MM) patients. Unfortunately, these immunotherapeutic approaches are hampered by the presence of a suppressive bone marrow mi
Autor:
Eline Menu, Karin Vanderkerken, Niels Vandewalle, Kim De Veirman, Ken Maes, Nathan De Beule, Sylvia Faict, Elke De Bruyne, Siyang Yan
Publikováno v:
Cancers
Cancers, Vol 11, Iss 11, p 1727 (2019)
Cancers, Vol 11, Iss 11, p 1727 (2019)
AXL belongs to the TAM (TYRO3, AXL, and MERTK) receptor family, a unique subfamily of the receptor tyrosine kinases. Their common ligand is growth arrest-specific protein 6 (GAS6). The GAS6/TAM signaling pathway regulates many important cell processe
Publikováno v:
Vrije Universiteit Brussel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::1767818186bdceea128f829902610583
https://researchportal.vub.be/en/publications/42e9869f-0070-4f6c-ba84-64a64c6ef534
https://researchportal.vub.be/en/publications/42e9869f-0070-4f6c-ba84-64a64c6ef534
Autor:
Rong Fan, Emma Verheye, Hatice Satilmis, Niels Vandewalle, Elke De Bruyne, Eline Menu, Nathan De Beule, Dirk Hose, Karin Vanderkerken, Karine Breckpot, Ken Maes, Kim De Veirman
Publikováno v:
Vrije Universiteit Brussel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::0c028be405c108152733ebe0c5f54719
https://researchportal.vub.be/en/publications/a72486f3-69b3-4a5f-bba5-c1529e2e70a4
https://researchportal.vub.be/en/publications/a72486f3-69b3-4a5f-bba5-c1529e2e70a4