Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Niels Schneberger"'
Autor:
Niels Schneberger, Philipp Hendricks, Martin F. Peter, Erik Gehrke, Sophie C. Binder, Paul-Albert Koenig, Stephan Menzel, Gavin H. Thomas, Gregor Hagelueken
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-11 (2024)
Abstract The tripartite ATP-independent periplasmic (TRAP) transporters enable Vibrio cholerae and Haemophilus influenzae to acquire sialic acid, aiding their colonization of human hosts. This process depends on SiaP, a substrate-binding protein (SBP
Externí odkaz:
https://doaj.org/article/a6c30ef2134942bfb74c4e1030f110c3
Autor:
Martin F. Peter, Jan A. Ruland, Yeojin Kim, Philipp Hendricks, Niels Schneberger, Jan Peter Siebrasse, Gavin H. Thomas, Ulrich Kubitscheck, Gregor Hagelueken
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract The tripartite ATP-independent periplasmic (TRAP) transporters use an extra cytoplasmic substrate binding protein (SBP) to transport a wide variety of substrates in bacteria and archaea. The SBP can adopt an open- or closed state depending o
Externí odkaz:
https://doaj.org/article/b83022bdcbc940eaaa4826707fa4d729
Autor:
Martin F. Peter, Jan A. Ruland, Peer Depping, Niels Schneberger, Emmanuele Severi, Jonas Moecking, Karl Gatterdam, Sarah Tindall, Alexandre Durand, Veronika Heinz, Jan Peter Siebrasse, Paul-Albert Koenig, Matthias Geyer, Christine Ziegler, Ulrich Kubitscheck, Gavin H. Thomas, Gregor Hagelueken
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Tripartite ATP-independent periplasmic (TRAP) transporters are widespread in bacteria and archaea. Here, the authors used cryo-EM and a range of biophysical techniques to study the structure of function of the sialic acid TRAP transporter HiSiaQM.
Externí odkaz:
https://doaj.org/article/77d7c0c6e18748a0b6f9d495c47f442b
Autor:
Christophe Rouillon, Niels Schneberger, Haotian Chi, Katja Blumenstock, Stefano Da Vela, Katrin Ackermann, Jonas Moecking, Martin F. Peter, Wolfgang Boenigk, Reinhard Seifert, Bela E. Bode, Jonathan L. Schmid-Burgk, Dmitri Svergun, Matthias Geyer, Malcolm F. White, Gregor Hagelueken
Publikováno v:
Nature
Funding information: M.G. and J.L.S.B. are funded by the Deutsche Forschungsgemeinschaft under Germany’s Excellence Strategy–EXC2151–390873048. M.F.W. acknowledges a European Research Council Advanced Grant (grant number 101018608) and the Chin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4d062fd4abf5ab686d29231fe864680
https://hdl.handle.net/10023/27669
https://hdl.handle.net/10023/27669
Autor:
Christophe Rouillon, Niels Schneberger, Haotian Chi, Martin F. Peter, Matthias Geyer, Wolfgang Boenigk, Reinhard Seifert, Malcolm F. White, Gregor Hagelueken
SummaryCRISPR antiviral defense systems such as the well-known DNA-targeting Cas9- and the more complex RNA-targeting type III systems are widespread in bacteria and archea 1, 2. The type III systems can orchestrate a complex antiviral response that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c19e5a774303fe4a61606f1f9ae34e9c
https://doi.org/10.1101/2021.12.06.471393
https://doi.org/10.1101/2021.12.06.471393
Autor:
Martin F. Peter, Peer Depping, Niels Schneberger, Emmanuele Severi, Karl Gatterdam, Sarah Tindall, Alexandre Durand, Veronika Heinz, Paul-Albert Koenig, Matthias Geyer, Christine Ziegler, Gavin H. Thomas, Gregor Hagelueken
SummaryTripartite ATP-independent periplasmic (TRAP) transporters are widespread in bacteria and archaea and provide important uptake routes for many metabolites 1–3. They consist of three structural domains, a soluble substrate-binding protein (P-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7a66b228670338f784790e398c5b5b77
https://doi.org/10.1101/2021.12.03.471092
https://doi.org/10.1101/2021.12.03.471092
Autor:
Thomas Mayr, Paul L. Dix, Sayed-Mohammad Hasheminasab, Chuanpit Hampel, Marc Sylvester, Niels Schneberger, Sarah Foerster, Gregor Hagelueken, Samikshan Dutta, Glen Kristiansen, Regine Schneider-Stock, Kaustubh Datta, Michael H. Muders
Publikováno v:
Cancer Research. 82:831-831
Upregulation of the non-tyrosine kinase receptor neuropilin-2 (NRP2) is described for several tumor entities and correlates with disease progression. Two membrane-anchored isoforms are transcribed from the NRP2 gene that only differ in their terminal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7a86f8dd7ddcc48939d96b8d20efd49e
https://doi.org/10.1158/1538-7445.am2022-831
https://doi.org/10.1158/1538-7445.am2022-831
Autor:
Martin F. Peter, Gregor Hagelueken, Gavin H. Thomas, Marijn de Boer, Janin Glaenzer, Niels Schneberger, Christian Gebhardt, Thorben Cordes
Publikováno v:
Journal of Molecular Biology, 433(3):166756. Academic Press
The pathogens Vibrio cholerae and Haemophilus influenzae use tripartite ATP-independent periplasmic transporters (TRAPs) to scavenge sialic acid from host tissues. They use it as a nutrient or to evade the innate immune system by sialylating surface
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc55921a28523155932bf19e964bcb9f
https://research.rug.nl/en/publications/8247a5f5-fc38-41f2-adcd-6cd7535212e1
https://research.rug.nl/en/publications/8247a5f5-fc38-41f2-adcd-6cd7535212e1
Autor:
Martin F. Peter, Marijn de Boer, Gavin H. Thomas, Thorben Cordes, Gregor Hagelueken, Christian Gebhardt, Janin Glaenzer, Niels Schneberger
The pathogensVibrio choleraeandHaemophilus influenzaeuse tripartite ATP-independent periplasmic transporters (TRAPs) to scavenge sialic acid from host tissues. They use it as a nutrient or to evade the innate immune system by sialylating surface lipo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5461087173aa0300c83b01878551b89d
https://doi.org/10.1101/2020.12.02.404004
https://doi.org/10.1101/2020.12.02.404004