Výsledky vyhledávání - "Niels O. S. Camara"

Akademický článek

A probiotic has differential effects on allergic airway inflammation in A/J and C57BL/6 mice and is correlated with the gut microbiome

Publikováno v: Microbiome, Vol 9, Iss 1, Pp 1-16 (2021)

Abstract The phenotypes of allergic airway diseases are influenced by the interplay between host genetics and the gut microbiota, which may be modulated by probiotics. We investigated the probiotic effects on allergic inflammation in A/J and C57BL/6

Externí odkaz: https://doaj.org/article/fe64bd89f1b949a2a32e5bc4468b05c1

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Akademický článek

Bifidobacterium Strains Present Distinct Effects on the Control of Alveolar Bone Loss in a Periodontitis Experimental Model

Autor: Natali Shimabukuro, Amália C. de S. Cataruci, Karin H. Ishikawa, Bruna E. de Oliveira, Dione Kawamoto, Ellen S. Ando-Suguimoto, Emmanuel Albuquerque-Souza, Jacques R. Nicoli, Caroline M. Ferreira, Jean de Lima, Manuela R. Bueno, Leandro B. R. da Silva, Pedro H. F. Silva, Michel R. Messora, Niels O. S. Camara, Maria Regina L. Simionato, Marcia P. A. Mayer

Publikováno v: Frontiers in Pharmacology, Vol 12 (2021)

Periodontitis is an inflammatory disease induced by a dysbiotic oral microbiome. Probiotics of the genus Bifidobacterium may restore the symbiotic microbiome and modulate the immune response, leading to periodontitis control. We evaluated the effect

Externí odkaz: https://doaj.org/article/553f364192d94798aa1d2fad00ce6005

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Akademický článek

Case Report: A Severe SARS-CoV-2 Infection in a Teenager With Angelman Syndrome

Publikováno v: Frontiers in Medicine, Vol 8 (2021)

Teenagers generally present mild to no symptoms of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. In the present report, we present the case of a 14-year-old boy with Angelman syndrome (AS) who presented with severe COVID-19

Externí odkaz: https://doaj.org/article/7fce7c8bb84e4e1dabf451f54ad3abba

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Akademický článek

Angiotensin-Converting Enzyme Inhibitor Protects Against Cisplatin Nephrotoxicity by Modulating Kinin B1 Receptor Expression and Aminopeptidase P Activity in Mice

Autor: Gabriel R. Estrela, Frederick Wasinski, Marcos F. Gregnani, Leandro C. Freitas-Lima, Adriano C. Arruda, Rafael Leite Morais, Denise MAC Malheiros, Niels O. S. Camara, João Bosco Pesquero, Michael Bader, Carlos Castilho Barros, Ronaldo Carvalho Araújo

Publikováno v: Frontiers in Molecular Biosciences, Vol 7 (2020)

Cisplatin is a highly effective chemotherapeutic agent. However, its use is limited by nephrotoxicity. Enalapril is an angiotensin I-converting enzyme inhibitor used for the treatment of hypertension, mainly through the reduction of angiotensin II fo

Externí odkaz: https://doaj.org/article/02b001a1ddfe41de95c51396dd191ae7

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Akademický článek

Innate And Adaptive Immunity are Progressively Activated in Parallel with Renal Injury in the 5/6 Renal Ablation Model

Autor: Camilla Fanelli, Simone C. A. Arias, Flavia G. Machado, Jessica K. Okuma, Denise M. A. C. Malheiros, Hatylas Azevedo, Carlos A. Moreira-Filho, Niels O. S. Camara, Clarice K. Fujihara, Roberto Zatz

Publikováno v: Scientific Reports, Vol 7, Iss 1, Pp 1-15 (2017)

Abstract The mechanisms triggering renal inflammation in chronic kidney disease (CKD) are unclear. We performed a detailed analysis of the time course of innate and adaptive immunity activation in the 5/6 renal ablation (Nx) model. Munich-Wistar rats

Externí odkaz: https://doaj.org/article/b5c021dc62174d1c8eff25e163a2c255

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Akademický článek

The Relevance of Thimet Oligopeptidase in the Regulation of Energy Metabolism and Diet-Induced Obesity

Publikováno v: Biomolecules, Vol 10, Iss 2, p 321 (2020)

Thimet oligopeptidase (EC 3.4.24.15; EP24.15; THOP1) is a potential therapeutic target, as it plays key biological functions in processing biologically functional peptides. The structural conformation of THOP1 provides a unique restriction regarding

Externí odkaz: https://doaj.org/article/cd23c3a4fd914795937480a86869742c

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Akademický článek

Mesenchymal Stem Cell Therapy Modulates the Inflammatory Response in Experimental Traumatic Brain Injury

Autor: Layla T. Galindo, Thais R. M. Filippo, Patricia Semedo, Carolina B. Ariza, Caroline M. Moreira, Niels O. S. Camara, Marimelia A. Porcionatto

Publikováno v: Neurology Research International, Vol 2011 (2011)

Therapy with mesenchymal stem cells (MSCs) has showed to be promising due to its immunomodulatory function. Traumatic brain injury (TBI) triggers immune response and release of inflammatory mediators, mainly cytokines, by glial cells creating a hosti

Externí odkaz: https://doaj.org/article/80bd2bd3dcad4253a91d74978c85f71c

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Akademický článek

A self-adjuvanted VLPs-based Covid-19 vaccine proven versatile, safe, and highly protective

Autor: Larissa Vuitika, Nelson Côrtes, Vanessa B. Malaquias, Jaqueline D. Q. Silva, Aline Lira, Wasim A. Prates-Syed, Lena F. Schimke, Daniela Luz, Ricardo Durães-Carvalho, Andrea Balan, Niels O. S. Câmara, Otavio Cabral-Marques, José E. Krieger, Mario H. Hirata, Gustavo Cabral-Miranda

Publikováno v: Scientific Reports, Vol 14, Iss 1, Pp 1-17 (2024)

Abstract Vaccination has played a critical role in mitigating COVID-19. Despite the availability of licensed vaccines, there remains a pressing need for improved vaccine platforms that provide high protection, safety, and versatility, while also redu

Externí odkaz: https://doaj.org/article/2d12047389a5455f9bfa8269f9ac2ba4

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