Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Niels Moeslund"'
Autor:
Marc Gjern Weiss, Anne Marye de Jong, Helene Seegert, Niels Moeslund, Hanno Maassen, Camilla Schjalm, Eline de Boer, Henri Leuvenink, Tom Eirik Mollnes, Marco Eijken, Anna Krarup Keller, Gerard Dijkstra, Bente Jespersen, Søren Erik Pischke
Publikováno v:
Transplant International, Vol 37 (2024)
Organs obtained from brain dead donors can have suboptimal outcomes. Activation of the innate immune system and translocation of intestinal bacteria could be causative. Thirty two pigs were assigned to control, brain death (BD), BD + luminal intestin
Externí odkaz:
https://doaj.org/article/591bbe74d3ef46c2a58fbe1dcbcd991a
Autor:
Oskar Kjærgaard Hørsdal, Niels Moeslund, Kristoffer Berg-Hansen, Roni Nielsen, Niels Møller, Hans Eiskjær, Henrik Wiggers, Nigopan Gopalasingam
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-14 (2024)
Abstract Background Lactate is traditionally recognized as a by-product of anaerobic metabolism. However, lactate is a preferred oxidative substrate for stressed myocardium. Exogenous lactate infusion increases cardiac output (CO). The exact mechanis
Externí odkaz:
https://doaj.org/article/65a963583d804b29bade278454b76dc0
Autor:
Jacob Marthinsen Seefeldt, Yaara Libai, Katrine Berg, Nichlas Riise Jespersen, Thomas Ravn Lassen, Frederik Flyvholm Dalsgaard, Pia Ryhammer, Michael Pedersen, Lars Bo Ilkjaer, Michiel A. Hu, Michiel E. Erasmus, Roni R. Nielsen, Hans Erik Bøtker, Oren Caspi, Hans Eiskjær, Niels Moeslund
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Normothermic regional perfusion (NRP) allows assessment of therapeutic interventions prior to donation after circulatory death transplantation. Sodium-3-hydroxybutyrate (3-OHB) increases cardiac output in heart failure patients and diminishe
Externí odkaz:
https://doaj.org/article/1a66841ddc5640f09a88e154cc730f6c
Autor:
Nigopan Gopalasingam, Niels Moeslund, Kristian Hylleberg Christensen, Kristoffer Berg‐Hansen, Jacob Seefeldt, Casper Homilius, Erik Nguyen Nielsen, Mie Ringgaard Dollerup, Aage K. Alstrup Olsen, Mogens Johannsen, Ebbe Boedtkjer, Niels Møller, Hans Eiskjær, Lars Christian Gormsen, Roni Nielsen, Henrik Wiggers
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 8 (2024)
Background The ketone body 3‐hydroxybutyrate (3‐OHB) increases cardiac output (CO) by 35% to 40% in healthy people and people with heart failure. The mechanisms underlying the effects of 3‐OHB on myocardial contractility and loading conditions
Externí odkaz:
https://doaj.org/article/5b06f1a0c49843c0ad0ad5a5885374ac
Autor:
Maibritt Meldgaard Arildsen, Christian Østergaard Mariager, Christoffer Vase Overgaard, Thomas Vorre, Martin Bøjesen, Niels Moeslund, Aage Kristian Olsen Alstrup, Lars Poulsen Tolbod, Mikkel Holm Vendelbo, Steffen Ringgaard, Michael Pedersen, Niels Henrik Buus
Publikováno v:
Journal of Imaging, Vol 10, Iss 9, p 209 (2024)
The aim was to establish combined H215O PET/MRI during ex vivo normothermic machine perfusion (NMP) of isolated porcine kidneys. We examined whether changes in renal arterial blood flow (RABF) are accompanied by changes of a similar magnitude in rena
Externí odkaz:
https://doaj.org/article/09db8a4378674b31947b0251cd87e24f
Autor:
Mathilde Emilie Kirk, Victor Tang Merit, Niels Moeslund, Simone Juel Dragsbaek, Jacob Valentin Hansen, Asger Andersen, Mads Dam Lyhne
Publikováno v:
Experimental Physiology, Vol 108, Iss 5, Pp 762-771 (2023)
Abstract Animal models of cardiovascular disease are often evaluated by invasive instrumentation for phenotyping. As no consensus exists, both open‐ and closed‐chest approaches are used, which might compromise rigour and reproducibility in precli
Externí odkaz:
https://doaj.org/article/1a5cce6db719456cb61c947e17558880
Autor:
Niels Moeslund, Imran A. Ertugrul, Michiel A. Hu, Frederik Flyvholm Dalsgaard, Lars Bo Ilkjaer, Pia Ryhammer, Michael Pedersen, Michiel E. Erasmus, Hans Eiskjaer
Publikováno v:
Journal of Heart and Lung Transplantation, 42(6), 730-740. ELSEVIER SCIENCE INC
Moeslund, N, Ertugrul, I A, Hu, M A, Dalsgaard, F F, Ilkjaer, L B, Ryhammer, P, Pedersen, M, Erasmus, M E & Eiskjaer, H 2023, ' Ex-situ oxygenated hypothermic machine perfusion in donation after circulatory death heart transplantation following either direct procurement or in-situ normothermic regional perfusion ', The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, vol. 42, no. 6, pp. 730-740 . https://doi.org/10.1016/j.healun.2023.01.014
Moeslund, N, Ertugrul, I A, Hu, M A, Dalsgaard, F F, Ilkjaer, L B, Ryhammer, P, Pedersen, M, Erasmus, M E & Eiskjaer, H 2023, ' Ex-situ oxygenated hypothermic machine perfusion in donation after circulatory death heart transplantation following either direct procurement or in-situ normothermic regional perfusion ', The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, vol. 42, no. 6, pp. 730-740 . https://doi.org/10.1016/j.healun.2023.01.014
BACKGROUND: Heart transplantation in donation after circulatory death (DCD) relies on warm perfusion using either in situ normothermic regional perfusion (NRP) or ex situ normothermic machine perfusion. In this study, we explore an alternative: oxyge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abf1370c1795ad758d39156ac4f8773a
https://hdl.handle.net/11370/9c503e7d-ccd5-4157-84c8-e40910513732
https://hdl.handle.net/11370/9c503e7d-ccd5-4157-84c8-e40910513732
Autor:
Zhang Long Zhang, Niels Moeslund, Michiel Andy Hu, Roland Hoffmann, Leonie Harmina Venema, Caroline Van De Wauwer, Wim Timens, Toshihiro Okamoto, Erik Alfons Maria Verschuuren, Henri Gerrit Derk Leuvenink, Hans Eiskjaer, Michiel Elardus Erasmus
Publikováno v:
ARTIFICIAL ORGANS, 46(11), 2179-2190. Wiley
Zhang, Z L, Moeslund, N, Hu, M A, Hoffmann, R, Venema, L H, Van De Wauwer, C, Timens, W, Okamoto, T, Verschuuren, E A M, Leuvenink, H G D, Eiskjaer, H & Erasmus, M E 2022, ' Establishing an economical and widely accessible donation after circulatory death animal abattoir model for lung research using ex vivo lung perfusion ', Artificial organs, vol. 46, no. 11, pp. 2179-2190 . https://doi.org/10.1111/aor.14345
Zhang, Z L, Moeslund, N, Hu, M A, Hoffmann, R, Venema, L H, Van De Wauwer, C, Timens, W, Okamoto, T, Verschuuren, E A M, Leuvenink, H G D, Eiskjaer, H & Erasmus, M E 2022, ' Establishing an economical and widely accessible donation after circulatory death animal abattoir model for lung research using ex vivo lung perfusion ', Artificial organs, vol. 46, no. 11, pp. 2179-2190 . https://doi.org/10.1111/aor.14345
Ex vivo lung perfusion (EVLP), is a platform that allows simultaneous testing and treatment of the lungs. However, use of EVLP is costly and requires access to lab animals and accompanying facilities. To increase the use of EVLP for research, we deve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5af21110f9737330013c25cc4744bd26
https://doi.org/10.1111/aor.14345
https://doi.org/10.1111/aor.14345
Autor:
Niels Moeslund, Zhang Long Zhang, Frederik Flyvholm Dalsgaard, Sif Bay Glenting, Lars Bo Ilkjaer, Pia Ryhammer, Johan Palmfeldt, Michael Pedersen, Michiel Erasmus, Hans Eiskjaer
Publikováno v:
Transplantation, 107(1), E3-E10. LIPPINCOTT WILLIAMS & WILKINS
Moeslund, N, Zhang, Z L, Dalsgaard, F F, Glenting, S B, Ilkjaer, L B, Ryhammer, P, Palmfeldt, J, Pedersen, M, Erasmus, M & Eiskjaer, H 2023, ' Clamping of the Aortic Arch Vessels During Normothermic Regional Perfusion Does Not Negatively Affect Donor Cardiac Function in Donation After Circulatory Death ', Transplantation, vol. 107, no. 1 . https://doi.org/10.1097/TP.0000000000004298
Moeslund, N, Zhang, Z L, Dalsgaard, F F, Glenting, S B, Ilkjaer, L B, Ryhammer, P, Palmfeldt, J, Pedersen, M, Erasmus, M & Eiskjaer, H 2023, ' Clamping of the Aortic Arch Vessels During Normothermic Regional Perfusion Does Not Negatively Affect Donor Cardiac Function in Donation After Circulatory Death ', Transplantation, vol. 107, no. 1 . https://doi.org/10.1097/TP.0000000000004298
Background. The hemodynamic effects of aortic arch vessel (AAV) clamping during normothermic regional perfusion (NRP) in donation after circulatory death is unknown. We investigated effects of AAV clamping during NRP compared with no clamping in a po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b10294ca457dd3deae352e30c097d1e1
https://doi.org/10.1097/tp.0000000000004298
https://doi.org/10.1097/tp.0000000000004298
Autor:
Niels Moeslund, Zhang Long Zhang, Lars Bo Ilkjaer, Pia Ryhammer, Christine Cramer, Johan Palmfeldt, Michael Pedersen, Michiel Elardus Erasmus, Steven Tsui, Hans Eiskjaer
Publikováno v:
Moeslund, N, Long Zhang, Z, Bo Ilkjaer, L, Ryhammer, P K, Cramer, C, Palmfeldt, J, Pedersen, M, Erasmus, M E, Tsui, S & Eiskjaer, H 2022, ' High Oxygenation During Normothermic Regional Perfusion After Circulatory Death Is Beneficial on Donor Cardiac Function in a Porcine Model ', Transplantation, vol. 106, no. 7, pp. e326-e335 . https://doi.org/10.1097/TP.0000000000004164
Transplantation, 106(7), E326-E335. LIPPINCOTT WILLIAMS & WILKINS
Transplantation, 106(7), E326-E335. LIPPINCOTT WILLIAMS & WILKINS
BACKGROUND: Thoracoabdominal normothermic regional perfusion (NRP) is a new method for in situ reperfusion and reanimation of potential donor organs in donation after circulatory death by reperfusion of the thoracic and abdominal organs with oxygenat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1c586aa081c876ca4356cb4eea4c6f5
https://hdl.handle.net/11370/96fc64ae-b3fa-4c54-96a1-d4a20b1c2f0b
https://hdl.handle.net/11370/96fc64ae-b3fa-4c54-96a1-d4a20b1c2f0b