Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Niels Kirk"'
Autor:
Daniel Snell, Tea Gunde, Stefan Warmuth, Bithi Chatterjee, Matthias Brock, Christian Hess, Maria Johansson, Alexandre Simonin, Fabio Mario Spiga, Christopher Weinert, Niels Kirk, Nicole Bassler, Lucia Campos Carrascosa, Naomi Flückiger, Robin Heiz, Sandro Wagen, Noreen Giezendanner, Alessandra Alberti, Yasemin Yaman, Dana Mahler, Dania Diem, Peter Lichtlen, David Urech
Publikováno v:
OncoImmunology, Vol 12, Iss 1 (2023)
ABSTRACTMesothelin (MSLN) is an attractive immuno-oncology target, but the development of MSLN-targeting therapies has been impeded by tumor shedding of soluble MSLN (sMSLN), on-target off-tumor activity, and an immunosuppressive tumor microenvironme
Externí odkaz:
https://doaj.org/article/37427098ffe74543b7338afdbca88496
Autor:
Daniel Snell, Niels Kirk, David Urech, Nicole Bassler, Lucia Campos Carrascosa, Pawel Chrom, Peter Lichtlen
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/c315729799aa4b2f93a1e6b1122a687a
Autor:
Bithi Chatterjee, Alexandre Simonin, Daniel Snell, Tea Gunde, Christian Hess, Matthias Brock, Stefan Warmuth, Christopher Weinert, Niels Kirk, Dania Diem, Robin Heiz, Dana Mahler, Sandro Wagen, Julia Zeberer, David Urech, Fabio Spiga, Nicole Bassler, Nina Schumacher, Yasemin Yaman, Bettina Bommer, Giorgio Gambino, Noreen Giezendanner, Benjamin Kuettner, Naomi Flueckiger
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
Externí odkaz:
https://doaj.org/article/f9b5336813e349368b3395de03a3a514
Autor:
Bithi Chatterjee, Alexandre Simonin, Daniel Snell, Tea Gunde, Christian Hess, Matthias Brock, Stefan Warmuth, Christopher Weinert, Niels Kirk, Dania Diem, Naomi Flückiger, Robin Heiz, Benjamin Küttner, Dana Mahler, Diego Morenzoni, Sandro Wagen, Julia Zeberer, David Urech
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Externí odkaz:
https://doaj.org/article/4194dd54118648d987b340b980a9bd3a
Autor:
Hitesh Mistry, Fernando Ortega, Bithi Chatterjee, Nicole Bassler, Niels Kirk, Julia Tietz, Belinda Wickihalder, Simone Muntwiler, Simon Carnal, Daniel Snell, Christophe Chassagnole
Publikováno v:
Regular and Young Investigator Award Abstracts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1ec3022adef995026ce43df33572a47d
https://doi.org/10.1136/jitc-2022-sitc2022.1293
https://doi.org/10.1136/jitc-2022-sitc2022.1293
Autor:
Daniel Snell, Tea Gunde, Stefan Warmuth, Peter Lichtlen, Linlin Liu, Shu-wen Teng, Lan Zhang, ChaoHsuan Pan, Peiqi Li, Julia Tietz, Matthias Brock, Alexandre Simonim, Christian Hess, Christopher Weinert, Maria Johansson, Bithi Chatterjeee, Nicole Bassler, Niels Kirk, Catia Mendes, Robin Heiz, Naomi Flueckiger, Dania Diem, Dana Mahler, Belinda Wickihalder, Simone Muntwiler, Sandro Wagen, Elmar vom Baur, Archie N. Tse, David Urech
Publikováno v:
Cancer Research. 82:2870-2870
Antagonistic molecules targeting the PD-1/PD-L1 axis have shown excellent activity in the clinic. However, the majority of patients do not respond to the therapy due to multifaceted reasons implicating a non-effective activation of the immune system
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3c66e2a2e3962a5347dc40d5b43afcb4
https://doi.org/10.1158/1538-7445.am2022-2870
https://doi.org/10.1158/1538-7445.am2022-2870
Autor:
Bithi Chatterjee, Christian Hess, Daniel Snell, Tea Gunde, Stefan Warmuth, Alexandre Simonin, Matthias Brock, Fabio Spiga, Maria Johansson, Christopher Weinert, Julia Tietz, Niels Kirk, Nicole Bassler, Dana Mahler, Dania Diem, Alessandra Carrella, Noreen Giezendanner, Alessandra Alberti, Giorgio Gambino, Belinda Wickihalder, Bettina Bommer, Simone Muntwiler, Yasemin Yaman, Naomi Flueckiger, Robin Heiz, Sandro Wagen, David Urech
Publikováno v:
Cancer Research. 82:2871-2871
CD3-based T cell engagers are highly potent therapeutic molecules which enable T cell-mediated cytotoxic activity toward cells expressing selected tumor-associated antigens. Alongside a highly potent anti-tumor activity, is the risk of on-target off-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2c7a4c193bb3250337bc2d869247fe0e
https://doi.org/10.1158/1538-7445.am2022-2871
https://doi.org/10.1158/1538-7445.am2022-2871
Autor:
Markus Schmid, Andreas Plückthun, Viviana Gradinaru, Niels Kirk, Sheena N. Smith, Branko Simic, Patrick C. Freitag, Dominik Brücher, Rajib Schubert
Publikováno v:
Proc Natl Acad Sci U S A
The goal of cancer-drug delivery is to achieve high levels of therapeutics within tumors with minimal systemic exposure that could cause toxicity. Producing biologics directly in situ where they diffuse and act locally is an attractive alternative to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::272ad5fc981d936d2f52471ace0551f4
https://doi.org/10.5167/uzh-210194
https://doi.org/10.5167/uzh-210194
Autor:
Tea Gunde, Dania Diem, Niels Kirk, Christopher Weinert, Dana Mahler, Matthias Brock, Sandro Wagen, David Urech, Robin Heiz, Julia Zeberer, Alexandre Simonin, Diego Morenzoni, Bithi Chatterjee, Daniel Snell, Benjamin Küttner, Christian Hess, Stefan Warmuth, Naomi Flückiger
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Background The effective treatment of solid tumors remains an unmet medical need. Several concepts exist to treat malignancies, including antibody-drug or -immunotoxin conjugates, immune checkpoint inhibition, CAR- T cells, as well as bispecific T ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3de97c9367d5ccc5b1179f3cfd9590c6
https://doaj.org/article/4194dd54118648d987b340b980a9bd3a
https://doaj.org/article/4194dd54118648d987b340b980a9bd3a
Autor:
Saskia Maria Gehrig, Matthias P. Hilty, Niels Kirk, Robert A. Jacobs, Simone Fenk, Christoph Siebenmann, Carsten Lundby, Anne-Kristine Meinild Lundby, Daniela Flück
Publikováno v:
The Journal of Physiology. 594:1151-1166
The role of hypoxia on skeletal muscle mitochondria is controversial. Studies superimposing exercise training on hypoxic exposure demonstrate an increase in skeletal muscle mitochondrial volume density (Mito(VD)) over equivalent normoxic training. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::99baf2eb25425ffb66fcf39990197b52
https://doi.org/10.1113/jp271118
https://doi.org/10.1113/jp271118