Zobrazeno 1 - 10
of 327
pro vyhledávání: '"Niels Jessen"'
Autor:
Mette Madsen, Henrik Støvring, Niels Jessen, Esben Thyssen Vestergaard, Kurt Kristensen, Ida Borreby Pedersen, Mads Kjolby, Astrid Johannesson Hjelholt, Ann-Margrethe Rønholt Christensen, Ditte Adolfsen, Jesper Sand Hjelle, Britta Kremke
Publikováno v:
BMJ Open, Vol 14, Iss 6 (2024)
Introduction Children and adolescents with recent-onset type 1 diabetes (T1D) commonly maintain a certain level of insulin production during the remission phase, which can last months to years. Preserving β-cell function can reduce T1D complications
Externí odkaz:
https://doaj.org/article/43be637eb1614ac797274565c63a08c0
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 9 (2024)
Background Skeletal muscle wasting is critical in patients with heart failure (HF). Whereas prior studies have employed appendicular lean mass (ALM) normalized by height squared to identify low skeletal muscle mass, the potential of ALM normalized to
Externí odkaz:
https://doaj.org/article/dcd82a9d3e3e45f7b268adfea3e9d0ed
Autor:
Xiaoguang Pan, Kunli Qu, Hao Yuan, Xi Xiang, Christian Anthon, Liubov Pashkova, Xue Liang, Peng Han, Giulia I. Corsi, Fengping Xu, Ping Liu, Jiayan Zhong, Yan Zhou, Tao Ma, Hui Jiang, Junnian Liu, Jian Wang, Niels Jessen, Lars Bolund, Huanming Yang, Xun Xu, George M. Church, Jan Gorodkin, Lin Lin, Yonglun Luo
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Thorough evaluation of CRISPR RNA-guided nucleases off-targets in cells is required for advancing gene therapies. Here the authors report SURRO-seq for the simultaneous investigation of thousands of off-target sites for therapeutic RNA-guided nucleas
Externí odkaz:
https://doaj.org/article/faf474f6db144a9c827ec4b0d699e6f7
Autor:
Fei Wang, Peiwen Ding, Xue Liang, Xiangning Ding, Camilla Blunk Brandt, Evelina Sjöstedt, Jiacheng Zhu, Saga Bolund, Lijing Zhang, Laura P. M. H. de Rooij, Lihua Luo, Yanan Wei, Wandong Zhao, Zhiyuan Lv, János Haskó, Runchu Li, Qiuyu Qin, Yi Jia, Wendi Wu, Yuting Yuan, Mingyi Pu, Haoyu Wang, Aiping Wu, Lin Xie, Ping Liu, Fang Chen, Jacqueline Herold, Joanna Kalucka, Max Karlsson, Xiuqing Zhang, Rikke Bek Helmig, Linn Fagerberg, Cecilia Lindskog, Fredrik Pontén, Mathias Uhlen, Lars Bolund, Niels Jessen, Hui Jiang, Xun Xu, Huanming Yang, Peter Carmeliet, Jan Mulder, Dongsheng Chen, Lin Lin, Yonglun Luo
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Pigs are important large animal models for biomedical research. Here, the authors construct a single-cell landscape of pig tissues, unravelling the phenotypic heterogeneity of blood endothelial cells in adipose tissues and the evolutionally conserved
Externí odkaz:
https://doaj.org/article/c21d50994fe24c6aa783a0e4f2146142
Publikováno v:
STAR Protocols, Vol 4, Iss 1, Pp 102008- (2023)
Summary: The ability of stem cells to activate and differentiate is critical for maintaining the regenerative capacity of skeletal muscle. Here, we detail steps for specific quantification and isolation of primary human fibro-adipogenic progenitors a
Externí odkaz:
https://doaj.org/article/9c3cb13ccddc4cf2ab31f1caaf658ca3
Autor:
Katrine M Lauritsen, Jens Hohwü Voigt, Steen Bønløkke Pedersen, Troels K Hansen, Niels Møller, Niels Jessen, Lars C Gormsen, Esben Søndergaard
Publikováno v:
Endocrine Connections, Vol 11, Iss 4, Pp 1-12 (2022)
SGLT2 inhibition induces an insulin-independent reduction in plasma glucose causing increased lipolysis and subsequent lipid oxidation by energy-consuming tissues. However, it is unknown whether SGLT2 inhibition also affects lip id storage in adipose
Externí odkaz:
https://doaj.org/article/07c525e6ebfb421f8701d94cd30c3b03
Autor:
Jonas Brorson Jensen, Ole L. Dollerup, Andreas B. Møller, Tine B. Billeskov, Emilie Dalbram, Sabina Chubanava, Mads V. Damgaard, Ryan W. Dellinger, Kajetan Trošt, Thomas Moritz, Steffen Ringgaard, Niels Møller, Jonas T. Treebak, Jean Farup, Niels Jessen
Publikováno v:
JCI Insight, Vol 7, Iss 19 (2022)
BACKGROUND During aging, there is a functional decline in the pool of muscle stem cells (MuSCs) that influences the functional and regenerative capacity of skeletal muscle. Preclinical evidence has suggested that nicotinamide riboside (NR) and pteros
Externí odkaz:
https://doaj.org/article/614077a593674c7a8b1130bb651c388e
Autor:
Henrik Holm Thomsen, Jonas Franck Olesen, Rasmus Aagaard, Bent Roni Ranghøj Nielsen, Thomas Schmidt Voss, Mads Vandsted Svart, Mogens Johannsen, Niels Jessen, Jens Otto L. Jørgensen, Nikolaj Rittig, Ermina Bach, Niels Møller
Publikováno v:
Physiological Reports, Vol 10, Iss 16, Pp n/a-n/a (2022)
Abstract Systemic administration of beta‐hydroxybutyrate (BHB) decreases whole‐body protein oxidation and muscle protein breakdown in humans. We aimed to determine any direct effect of BHB on skeletal muscle protein turnover when administered loc
Externí odkaz:
https://doaj.org/article/8132f763b5bd45d786d79ddae11579b7
Autor:
Fei Wang, Peiwen Ding, Xue Liang, Xiangning Ding, Camilla Blunk Brandt, Evelina Sjöstedt, Jiacheng Zhu, Saga Bolund, Lijing Zhang, Laura P. M. H. de Rooij, Lihua Luo, Yanan Wei, Wandong Zhao, Zhiyuan Lv, János Haskó, Runchu Li, Qiuyu Qin, Yi Jia, Wendi Wu, Yuting Yuan, Mingyi Pu, Haoyu Wang, Aiping Wu, Lin Xie, Ping Liu, Fang Chen, Jacqueline Herold, Joanna Kalucka, Max Karlsson, Xiuqing Zhang, Rikke Bek Helmig, Linn Fagerberg, Cecilia Lindskog, Fredrik Pontén, Mathias Uhlen, Lars Bolund, Niels Jessen, Hui Jiang, Xun Xu, Huanming Yang, Peter Carmeliet, Jan Mulder, Dongsheng Chen, Lin Lin, Yonglun Luo
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-2 (2022)
Externí odkaz:
https://doaj.org/article/d4cf4c7a7e6b438db4f2246d1eed4075
Autor:
Torben Hansen, Henrik T Sørensen, Allan Vaag, Reimar W Thomsen, Ivan Brandslund, Henning Beck-Nielsen, Emma Ahlqvist, Jens Steen Nielsen, Charlotte Brøns, Diana Hedevang Christensen, Jørgen Rungby, Peter Vestergaard, Niels Jessen, Michael H Olsen, Sia K Nicolaisen, Jacob V Stidsen, Kurt Hojlund, Sonia García-Calzón, Charlotte Ling
Publikováno v:
BMJ Open Diabetes Research & Care, Vol 10, Iss 2 (2022)
Externí odkaz:
https://doaj.org/article/ace3725727b64bbb8a7b40d050374654