Zobrazeno 1 - 10
of 214
pro vyhledávání: '"Niels H H Heegaard"'
Autor:
Douglas Nogueira Perez Oliveira, Anting Liu Carlsen, Niels H H Heegaard, Kira Philipsen Prahm, Ib Jarle Christensen, Claus K Høgdall, Estrid V Høgdall
Publikováno v:
PLoS ONE, Vol 14, Iss 11, p e0225249 (2019)
BackgroundOvarian cancer is the fifth most common cancer in women worldwide. Moreover, there are no reliable minimal invasive tests to secure the diagnosis of malignant pelvic masses. Cell-free, circulating microRNAs have the potential as diagnostic
Externí odkaz:
https://doaj.org/article/9b028ec4fa42410584eabf110c6fe020
Autor:
Niels H H Heegaard, Anting Liu Carlsen, Berit Lilje, Kim Lee Ng, Mette E Rønne, Henrik L Jørgensen, Henriette Sennels, Jan Fahrenkrug
Publikováno v:
PLoS ONE, Vol 11, Iss 8, p e0160577 (2016)
A 24-hour light and dark cycle-dependent rhythmicity pervades physiological processes in virtually all living organisms including humans. These regular oscillations are caused by external cues to endogenous, independent biological time-keeping system
Externí odkaz:
https://doaj.org/article/04f5ce3edb644d58bad7ce911ee80dda
Autor:
Jacob Sode, Ulla Vogel, Steffen Bank, Paal Skytt Andersen, Merete Lund Hetland, Henning Locht, Niels H H Heegaard, Vibeke Andersen
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0139781 (2015)
ObjectivesTo determine whether genetic variation within genes related to the Toll-like receptor, inflammasome and interferon-γ pathways contributes to the differences in treatment response to tumour necrosis factor inhibitors (anti-TNF) in patients
Externí odkaz:
https://doaj.org/article/070f970fa152475f9e251b5b65454344
Autor:
Christian Lood, Helena Tydén, Birgitta Gullstrand, Cecilia Klint, Christina Wenglén, Christoffer T Nielsen, Niels H H Heegaard, Andreas Jönsen, Robin Kahn, Anders A Bengtsson
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0125109 (2015)
Serotonin, a highly pro-inflammatory molecule released by activated platelets, is formed by tryptophan. Tryptophan is also needed in the production of kynurenine, a process mediated by the type I interferon (IFN)-regulated rate-limiting enzyme indole
Externí odkaz:
https://doaj.org/article/7a756920bfbf4f0e9a13407064e808ee
Autor:
Helle H Nielsen, Hans C Beck, Lars P Kristensen, Mark Burton, Tunde Csepany, Magdolna Simo, Peter Dioszeghy, Tobias Sejbaek, Manuela Grebing, Niels H H Heegaard, Zsolt Illes
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0139659 (2015)
Inflammatory demyelinating diseases of the CNS comprise a broad spectrum of diseases like neuromyelitis optica (NMO), NMO spectrum disorders (NMO-SD) and multiple sclerosis (MS). Despite clear classification criteria, differentiation can be difficult
Externí odkaz:
https://doaj.org/article/0de9f23466e84c92a8c90d2a1defe7d5
Autor:
Jacob Sode, Ulla Vogel, Steffen Bank, Paal Skytt Andersen, Marianne Kragh Thomsen, Merete Lund Hetland, Henning Locht, Niels H H Heegaard, Vibeke Andersen
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e100361 (2014)
ObjectiveMany patients with rheumatoid arthritis (RA) benefit from tumor necrosis factor-α blocking treatment (anti-TNF), but about one third do not respond. The objective of this study was to replicate and extend previously found associations betwe
Externí odkaz:
https://doaj.org/article/99897076b05c4c918622565bb3bb7063
Autor:
Niels H H Heegaard, Mikkel West-Nørager, Julia T Tanassi, Gunnar Houen, Lotte Nedergaard, Claus Høgdall, Estrid Høgdall
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e30997 (2012)
BackgroundCirculating autoantibodies occur more frequently in cancer patients than in patients without cancer.Methods and findingsWe examined sera from patients referred for pelvic mass symptoms to a tertiary university clinic. A total of 127 were di
Externí odkaz:
https://doaj.org/article/2c3304315d514daba24c5dbedd9d2395
Autor:
Mauno Vihinen, Anting Liu Carlsen, Niels H. H. Heegaard, Gabriel N. Teku, Dirk M. Wuttge, Roger Hesselstrand, Marie Wildt, Göran Rådegran
Publikováno v:
Rheumatology (Oxford, England)
Wuttge, D M, Carlsen, A L, Teku, G, Wildt, M, Rådegran, G, Vihinen, M, Heegaard, N H H & Hesselstrand, R 2022, ' Circulating Plasma microRNAs In Systemic Sclerosis-Associated Pulmonary Arterial Hypertension ', Rheumatology (Oxford, England), vol. 61, no. 1, pp. 309–318 . https://doi.org/10.1093/rheumatology/keab300
Wuttge, D M, Carlsen, A L, Teku, G, Wildt, M, Rådegran, G, Vihinen, M, Heegaard, N H H & Hesselstrand, R 2022, ' Circulating Plasma microRNAs In Systemic Sclerosis-Associated Pulmonary Arterial Hypertension ', Rheumatology (Oxford, England), vol. 61, no. 1, pp. 309–318 . https://doi.org/10.1093/rheumatology/keab300
Objectives SSc-associated pulmonary arterial hypertension (SSc-APAH) is a late but devastating complication of SSc. Early identification of SSc-APAH may improve survival. We examined the role of circulating miRNAs in SSc-APAH. Methods Using quantitat
Autor:
Per Wittenhagen, Didde Lauritzen, Rasmus Gaardskær Nielsen, Bente Utoft Andreassen, Lone Klinge, Anne-Mette Walsted, Niels H. H. Heegaard, Mette Neland
Publikováno v:
Lauritzen, D, Andreassen, B U, Heegaard, N H H, Klinge, L G, Walsted, A-M, Neland, M, Nielsen, R G & Wittenhagen, P 2018, ' Pediatric Inflammatory Bowel Diseases : Should We Be Looking for Kidney Abnormalities? ', Inflammatory Bowel Diseases, vol. 24, no. 12, pp. 2599–2605 . https://doi.org/10.1093/ibd/izy166
Background: Kidney disease has been reported in adults with inflammatory bowel disease (IBD) and is regarded an extraintestinal manifestation or more rarely a side effect of the medical treatment.Methods: In this cross-sectional study we describe the
Autor:
Marco Bo Hansen, D. S. Nellemann, N. Sandhu, Henrik Ullum, J. H. von Stemann, Niels H. H. Heegaard, Rune Larsen, Erik Sørensen
Publikováno v:
Larsen, R, Sandhu, N, Heegaard, N H H, Ullum, H, von Stemann, J H, Sørensen, E, Nellemann, D S & Hansen, M B 2018, ' Changes in circulating inflammatory markers following febrile non-haemolytic transfusion reactions to leucoreduced red cells ', Vox Sanguinis, vol. 113, no. 1, pp. 76–79 . https://doi.org/10.1111/vox.12607
It would be desirable to be able to distinguish fever as a result of febrile non-haemolytic transfusion reactions (FNHTR) from other febrile conditions. To further characterize the inflammatory feature of FNHTR, we measured a large panel of inflammat