Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Niels Geudens"'
Autor:
Catherine Cesa-Luna, Niels Geudens, Léa Girard, Vic De Roo, Hassan R. Maklad, José C. Martins, Monica Höfte, René De Mot
Publikováno v:
mSystems, Vol 8, Iss 1 (2023)
ABSTRACT A major source of pseudomonad-specialized metabolites is the nonribosomal peptide synthetases (NRPSs) assembling siderophores and lipopeptides. Cyclic lipopeptides (CLPs) of the Mycin and Peptin families are frequently associated with, but n
Externí odkaz:
https://doaj.org/article/f4b8cf278b8b420f97c15b00d45ef46e
Autor:
Penthip Muangkaew, Vic De Roo, Lu Zhou, Léa Girard, Catherine Cesa-Luna, Monica Höfte, René De Mot, Annemieke Madder, Niels Geudens, José C. Martins
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 18, p 14302 (2023)
In Pseudomonas lipopeptides, the D-configuration of amino acids is generated by dedicated, dual-function epimerization/condensation (E/C) domains. The increasing attention to stereochemistry in lipopeptide structure elucidation efforts has revealed m
Externí odkaz:
https://doaj.org/article/d68069bd9b27454ba49d3a2ef8e152fb
Autor:
Jessica Steigenberger, Catherine Mergen, Vic De Roo, Niels Geudens, José C. Martins, Heiko Heerklotz
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
Tolaasin II is an amphiphilic, membrane-active, cyclic lipopeptide produced by Pseudomonas tolaasii and is responsible for brown blotch disease in mushroom. To better understand the mode of action and membrane selectivity of tolaasin II and related l
Externí odkaz:
https://doaj.org/article/da342bf6c75b410baab41a27bd15ae79
Autor:
Vic De Roo, Yentl Verleysen, Benjámin Kovács, Matthias De Vleeschouwer, Penthip Muangkaew, Léa Girard, Monica Höfte, René De Mot, Annemieke Madder, Niels Geudens, José C. Martins
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 4 (2022)
ABSTRACT Cyclic lipopeptides (CLiPs) are secondary metabolites secreted by a range of bacterial phyla. CLiPs from Pseudomonas in particular, display diverse structural variations in terms of the number of amino acid residues, macrocycle size, amino a
Externí odkaz:
https://doaj.org/article/245622bbff19407ba87dc418b727cb5f
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
Pseudodesmin A (PSD) is a cyclic lipodepsipeptide produced by Pseudomonas that kills certain bacteria at MIC1/2 in the single micromolar range, probably by permeabilizing their cellular membranes. Synthetic PSD variants, where the native decanoic (C1
Externí odkaz:
https://doaj.org/article/c1631a53273d4be1b24f7600102fa40b
Autor:
Feyisara E. Oni, Niels Geudens, Amayana Adiobo, Olumide O. Omoboye, Elsie A. Enow, Joseph T. Onyeka, Ayodeji E. Salami, René De Mot, José C. Martins, Monica Höfte
Publikováno v:
Microorganisms, Vol 8, Iss 7, p 1079 (2020)
Pseudomonas cyclic lipopeptides (CLPs) are encoded non-ribosomally by biosynthetic gene clusters (BGCs) and possess diverse biological activities. In this study, we conducted chemical structure and BGC analyses with antimicrobial activity assays for
Externí odkaz:
https://doaj.org/article/c2d7b694b1964e50b2f9b0419fdf22a1
Autor:
Niels Geudens, José C. Martins
Publikováno v:
Frontiers in Microbiology, Vol 9 (2018)
Cyclic lipodepsipeptides produced by Pseudomonas spp. (Ps-CLPs) are biosurfactants that constitute a diverse class of versatile bioactive natural compounds with promising application potential. While chemically diverse, they obey a common structural
Externí odkaz:
https://doaj.org/article/0859e37591ac427fad98c086b10845e8
Autor:
Olumide Owolabi Omoboye, Niels Geudens, Matthieu Duban, Mickaël Chevalier, Christophe Flahaut, José C. Martins, Valérie Leclère, Feyisara Eyiwumi Oni, Monica Höfte
Publikováno v:
Molecules, Vol 24, Iss 22, p 4170 (2019)
Pseudomonas species are metabolically robust, with capacity to produce secondary metabolites including cyclic lipopeptides (CLPs). Herein we conducted a chemical analysis of a crude CLP extract from the cocoyam rhizosphere-derived biocontrol strain P
Externí odkaz:
https://doaj.org/article/2e2b8aa3ec4f44ebb03b7b4a7ca60885
Autor:
Niels Geudens, Benjámin Kovács, Davy Sinnaeve, Feyisara Eyiwumi Oni, Monica Höfte, José C. Martins
Publikováno v:
Molecules, Vol 24, Iss 12, p 2257 (2019)
Cyclic lipodepsipeptides or CLiPs from Pseudomonas are secondary metabolites that mediate a wide range of biological functions for their producers, and display antimicrobial and anticancer activities. Direct interaction of CLiPs with the cellular mem
Externí odkaz:
https://doaj.org/article/96e04247f38f438da5c94eeea05ade60
Autor:
Jessica Steigenberger, Yentl Verleysen, Niels Geudens, Annemieke Madder, José C. Martins, Heiko Heerklotz
Publikováno v:
BIOPHYSICAL JOURNAL
Cyclic lipopeptides (CLiPs) have many biological functions, including the selective permeabilization of target membranes, and technical and medical applications. We studied the anionic CLiP viscosin from Pseudomonas along with a neutral analog, pseud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::039e5b9f8f920c44fd2e8d81e99208e1
https://pubmed.ncbi.nlm.nih.gov/35927958
https://pubmed.ncbi.nlm.nih.gov/35927958