Zobrazeno 1 - 10
of 1 167
pro vyhledávání: '"Niels De"'
Autor:
Anne-Sophie van der Werf't Lam, Noah C. Helderman, Arnoud Boot, Diantha Terlouw, Hans Morreau, Hailian Mei, Rebecca E.E. Esveldt-van Lange, Inge M.M. Lakeman, Christi J. van Asperen, Emmelien Aten, Nandy Hofland, Pia A.M. de Koning Gans, Emily Rayner, Carli Tops, Niels de Wind, Tom van Wezel, Maartje Nielsen
Publikováno v:
Experimental and Molecular Pathology, Vol 140, Iss , Pp 104940- (2024)
Functional analyses are the main method to classify mismatch repair (MMR) gene variants of uncertain significance (VUSs). However, the pathogenicity remains unclear for many variants because of conflicting results between clinical, molecular, and fun
Externí odkaz:
https://doaj.org/article/495ee08f0dc6450c81f1b9f564d08794
Publikováno v:
Challenging Glass Conference Proceedings, Vol 9 (2024)
Reuse of entire insulating glas units (IGUs) in façades is a high-level circular strategy to decrease material and energy use and CO2 emissions. Yet, how many post-consumer IGUs are fit for such a direct reapplication and comply to building regulati
Externí odkaz:
https://doaj.org/article/3dd458d57f504b309bdfefb857d9eb1f
Publikováno v:
Buildings, Vol 14, Iss 7, p 1888 (2024)
The growing awareness of the value of temporary use projects in reactivating unused buildings has led to their increased implementation and acceptance by local authorities and building owners. Encouraging such reactivation can help to address the lar
Externí odkaz:
https://doaj.org/article/8559ae9e1fda42fa8a930aadc5416e74
Autor:
Changpei Gan, Jing Wang, Alejandra Martínez-Chávez, Michel Hillebrand, Niels de Vries, Joke Beukers, Els Wagenaar, Yaogeng Wang, Maria C. Lebre, Hilde Rosing, Sjoerd Klarenbeek, Rahmen Bin Ali, Colin Pritchard, Ivo Huijbers, Jos H. Beijnen, Alfred H. Schinkel
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 13, Iss 2, Pp 618-631 (2023)
The mammalian carboxylesterase 1 (Ces1/CES1) family comprises several enzymes that hydrolyze many xenobiotic chemicals and endogenous lipids. To investigate the pharmacological and physiological roles of Ces1/CES1, we generated Ces1 cluster knockout
Externí odkaz:
https://doaj.org/article/87e193186c58427c9b561d417264b90f
Publikováno v:
Sensors, Vol 24, Iss 3, p 936 (2024)
In urban intersections, the sensory capabilities of autonomous vehicles (AVs) are often hindered by visual obstructions, posing significant challenges to their robust and safe operation. This paper presents an implementation study focused on enhancin
Externí odkaz:
https://doaj.org/article/03ea03def8f5404db02be637ddad1943
Autor:
Sharath Anugula, Zhiquan Li, Yuan Li, Alexander Hendriksen, Peter Bjarn Christensen, Lin Wang, Jonathan M. Monk, Niels de Wind, Vilhelm A. Bohr, Claus Desler, Robert K. Naviaux, Lene Juel Rasmussen
Publikováno v:
Heliyon, Vol 9, Iss 6, Pp e17392- (2023)
Replication stress, caused by Rev1 deficiency, is associated with mitochondrial dysfunction, and metabolic stress. However, the overall metabolic alterations and possible interventions to rescue the deficits due to Rev1 loss remain unclear. Here, we
Externí odkaz:
https://doaj.org/article/c97fbe219a0b4f4aba53cc5c825abbed
Autor:
Stijn Stroobants, Kim Dockx, Hans Scheers, Vere Borra, Niels De Brier, Sarah Verlinden, Karen Lauwers, Philippe Vandekerckhove, Emmy De Buck
Publikováno v:
International Journal of First Aid Education, Vol 6, Iss 1, Pp 37–60-37–60 (2023)
Background: Family and friends are particularly well placed to recognize early signs of mental health problems, provide initial support, and refer to professional help if needed. This project aimed to develop evidence-based guidance materials for lay
Externí odkaz:
https://doaj.org/article/7d3ffbaad04a421485d0ef7349fa06ed
Autor:
Myrthe A. M. van Delft, Esil Aleyd, Richard van der Mast, Niels de Jong, Louis Boon, Peter J. Simons, Marjolein van Egmond
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionImmunoglobulin A (IgA) is mostly considered as a non-inflammatory regulator at mucosal areas. However, previous work of our group showed that IgA can also be involved in disease pathology, because it provides a potent stimulus to activate
Externí odkaz:
https://doaj.org/article/1896f0aee4b44201819b5da2463403ec
Autor:
Frank Kolligs, Dirk Arnold, Rita Golfieri, Maciej Pech, Bora Peynircioglu, Thomas Pfammatter, Maxime Ronot, Bruno Sangro, Niklaus Schaefer, Geert Maleux, Graham Munneke, Helena Pereira, Bleranda Zeka, Niels de Jong, Thomas Helmberger, Thomas Albrecht, Olivier D’Archambeau, Tugsan Balli, Sadik Bilgic, Allan Bloom, Roberto Cioni, Roman Fischbach, Patrick Flamen, Laurent Gerard, Gerd Grözinger, Marcus Katoh, Michael Koehler, Jan Robert Kröger, Christiane Kuhl, Franco Orsi, Murat Özgün, Peter Reimer, Axel Schmid, Alessandro Vit
Publikováno v:
JHEP Reports, Vol 5, Iss 2, Pp 100633- (2023)
Background & Aims: Transarterial radioembolization (TARE) with Yttrium-90 resin microspheres is an established treatment option for patients with hepatocellular carcinoma (HCC). However, optimising treatment application and patient selection remains
Externí odkaz:
https://doaj.org/article/15aee89267114bf9abbf4e67188f6052
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract Scanning transmission electron microscopy (STEM) provides structural analysis with sub-angstrom resolution. But the pixel-by-pixel scanning process is a limiting factor in acquiring high-speed data. Different strategies have been implemented
Externí odkaz:
https://doaj.org/article/e2dbd5205327416b8f2b7b29cfb08690