Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Niels Alberts"'
Autor:
Matteo Bason, Melanie Meister-Broekema, Niels Alberts, Pascale Dijkers, Steven Bergink, Ody C.M. Sibon, Harm H. Kampinga
Publikováno v:
Neurobiology of Disease, Vol 124, Iss , Pp 108-117 (2019)
Several neurodegenerative diseases like Huntington's, a polyglutamine (PolyQ) disease, are initiated by protein aggregation in neurons. Furthermore, these diseases are also associated with a multitude of responses in non-neuronal cells in the brain,
Externí odkaz:
https://doaj.org/article/707dd10d578e4961a0b1db8e93cc715e
Autor:
Nadinath B Nillegoda, Antonia Stank, Duccio Malinverni, Niels Alberts, Anna Szlachcic, Alessandro Barducci, Paolo De Los Rios, Rebecca C Wade, Bernd Bukau
Publikováno v:
eLife, Vol 6 (2017)
Hsp70 participates in a broad spectrum of protein folding processes extending from nascent chain folding to protein disaggregation. This versatility in function is achieved through a diverse family of J-protein cochaperones that select substrates for
Externí odkaz:
https://doaj.org/article/a20258da37e549069a38cb1d780a7bdf
Autor:
Yasith Mathangasinghe, Niels Alberts, Carlos J. Rosado, Dezerae Cox, Natalie L. Payne, Angelique R. Ormsby, Keziban Merve Alp, Roman Sakson, Sanjeev Uthishtran, Thomas Ruppert, Senthil Arumugam, Danny M. Hatters, Harm H. Kampinga, Nadinath B. Nillegoda
The collapse of protein homeostasis manifests itself in a toxic protein aggregation cascade, which is associated with degenerative diseases and aging. To solubilize aggregates, dedicated protein disaggregases exist in unicellular organisms, but these
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a69941d43c1683cb66bf8250eaca6b39
https://doi.org/10.1101/2022.06.25.497591
https://doi.org/10.1101/2022.06.25.497591
Publikováno v:
Journal of Visualized Experiments. JOURNAL OF VISUALIZED EXPERIMENTS
ISSUE=151;ISSN=1940-087X;TITLE=Journal of Visualized Experiments
ISSUE=151;ISSN=1940-087X;TITLE=Journal of Visualized Experiments
J-domain proteins (JDPs) form the largest and the most diverse co-chaperone family in eukaryotic cells. Recent findings show that specific members of the JDP family could form transient heterocomplexes in eukaryotes to fine-tune substrate selection f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d307fc9d8fae0f1b9bdd21c241c214d
https://research.rug.nl/en/publications/5f8d209d-c62a-40ea-9e76-4a3e23aacd79
https://research.rug.nl/en/publications/5f8d209d-c62a-40ea-9e76-4a3e23aacd79
Autor:
Anna Szlachcic, Rebecca C. Wade, Antonia Stank, Bernd Bukau, Nadinath B. Nillegoda, Paolo De Los Rios, Alessandro Barducci, Niels Alberts, Duccio Malinverni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2d97b09624c854722765bc38ced40b16
https://doi.org/10.7554/elife.24560.020
https://doi.org/10.7554/elife.24560.020
Autor:
Rebecca C. Wade, Niels Alberts, Bernd Bukau, Antonia Stank, Alessandro Barducci, Nadinath B. Nillegoda, Duccio Malinverni, Paolo De Los Rios, Anna Szlachcic
Publikováno v:
eLife
eLife, Vol 6 (2017)
eLife, eLife Sciences Publication, 2017, 6, ⟨10.7554/eLife.24560⟩
eLife, Vol 6 (2017)
eLife, eLife Sciences Publication, 2017, 6, ⟨10.7554/eLife.24560⟩
Hsp70 participates in a broad spectrum of protein folding processes extending from nascent chain folding to protein disaggregation. This versatility in function is achieved through a diverse family of J-protein cochaperones that select substrates for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82a5da5b492c019289c08fd8f5ba48d8
https://pubmed.ncbi.nlm.nih.gov/28504929
https://pubmed.ncbi.nlm.nih.gov/28504929
Publikováno v:
The Journal of Neuroscience, 34(14):10.1523/JNEUROSCI.0135-14.2014, 4757-4759. Oxford University Press
The microtubule-binding protein tau is widely expressed in neurons, where it supports the assembly and stabilization of microtubules ([Fong et al., 2013][1]; [Spillantini and Goedert, 2013][2]). Under normal physiological conditions, tau lacks second
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adf87b02c77c6a75999a8ffba1c94098
https://research.rug.nl/en/publications/24598444-e061-4b46-b7e6-0c3a126237c1
https://research.rug.nl/en/publications/24598444-e061-4b46-b7e6-0c3a126237c1
Autor:
Niels Albertsen
Publikováno v:
Ambiances (2019)
Gernot Böhme proposes the concept of atmosphere as the basic concept of a new aesthetics without a point of departure in art. This article speculates on some possible urban implications of this concept. To start with, I present various ontological a
Externí odkaz:
https://doaj.org/article/7dbbdf3f026f4d3a85144b7bdedd7854