Zobrazeno 1 - 10
of 142
pro vyhledávání: '"Niels, Galjart"'
Autor:
Teruyoshi Hirayama, Yuuki Kadooka, Etsuko Tarusawa, Sei Saitoh, Hisako Nakayama, Natsumi Hoshino, Soichiro Nakama, Takahiro Fukuishi, Yudai Kawanishi, Hiroki Umeshima, Koichi Tomita, Yumiko Yoshimura, Niels Galjart, Kouichi Hashimoto, Nobuhiko Ohno, Takeshi Yagi
Publikováno v:
Acta Neuropathologica Communications, Vol 10, Iss 1, Pp 1-17 (2022)
Abstract CCCTC-binding factor (CTCF) has a key role in higher-order chromatin architecture that is important for establishing and maintaining cell identity by controlling gene expression. In the mature cerebellum, CTCF is highly expressed in Purkinje
Externí odkaz:
https://doaj.org/article/a72517b6649347dfb51706d49c79da9c
Autor:
Willem K. Smits, Carlo Vermeulen, Rico Hagelaar, Shunsuke Kimura, Eric M. Vroegindeweij, Jessica G.C.A.M. Buijs-Gladdines, Ellen van de Geer, Marjon J.A.M. Verstegen, Erik Splinter, Simon V. van Reijmersdal, Arjan Buijs, Niels Galjart, Winfried van Eyndhoven, Max van Min, Roland Kuiper, Patrick Kemmeren, Charles G. Mullighan, Wouter de Laat, Jules P.P. Meijerink
Publikováno v:
Cell Reports, Vol 42, Iss 4, Pp 112373- (2023)
Summary: Monoallelic inactivation of CCCTC-binding factor (CTCF) in human cancer drives altered methylated genomic states, altered CTCF occupancy at promoter and enhancer regions, and deregulated global gene expression. In patients with T cell acute
Externí odkaz:
https://doaj.org/article/6b893ca121c74b21b92992c09f74bf69
Autor:
Anna Klaus, Thomas Clapes, Laurent Yvernogeau, Sreya Basu, Bart Weijts, Joris Maas, Ihor Smal, Niels Galjart, Catherine Robin
Publikováno v:
Cell Reports, Vol 39, Iss 11, Pp 110957- (2022)
Summary: Hematopoietic stem cells (HSCs) express a large variety of cell surface receptors that are associated with acquisition of self-renewal and multipotent properties. Correct expression of these receptors depends on a delicate balance between ce
Externí odkaz:
https://doaj.org/article/b4488eee3f6c4c19b6336b0c4501bb66
Autor:
Arantxa Pérez-García, Ester Marina-Zárate, Ángel F. Álvarez-Prado, Jose M. Ligos, Niels Galjart, Almudena R. Ramiro
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
Activated B cells differentiate into antibody-producing plasma cells in the germinal centre in secondary lymphoid organs. Here the authors show that this differentiation process and related transcription programs are modulated by the transcription fa
Externí odkaz:
https://doaj.org/article/75b203f03cb5452fbe3bed7da17951d3
Autor:
Carmen Laura Sayas, Sreya Basu, Michael van der Reijden, Eugenio Bustos-Morán, Marcia Liz, Monica Sousa, Wilfred F. J. van IJcken, Jesus Avila, Niels Galjart
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 13 (2019)
Mammalian cytoplasmic linker associated protein 1 and -2 (CLASP1 and -2) are microtubule (MT) plus-end tracking proteins that selectively stabilize MTs at the edge of cells and that promote MT nucleation and growth at the Golgi, thereby sustaining ce
Externí odkaz:
https://doaj.org/article/b590555e993347499563bdf3b672ad08
Publikováno v:
Cardiovascular Research.
The cardiac sodium channel NaV1.5 is an essential modulator of cardiac excitability, with decreased NaV1.5 levels at the plasma membrane and consequent reduction in sodium current (INa) leading to potentially lethal cardiac arrhythmias. NaV1.5 is dis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b3bf5e02d5bf7f4b71976480dcdd425a
https://doi.org/10.1093/cvr/cvad052
https://doi.org/10.1093/cvr/cvad052
Autor:
Ana L Pereira, Luísa T. Ferreira, Tiago Ferreira da Silva, Martine Jaegle, Marjon Buscop-van Kempen, Anne Boerema-de Munck, Wilfred van IJcken, Pedro Brites, Robbert J. Rottier, Niels Galjart, Helder Maiato
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ec6e8c61123d76d3084ec7b28802787f
https://doi.org/10.15252/rc.2022136631
https://doi.org/10.15252/rc.2022136631
Autor:
Marco Novais-Cruz, Maria Alba Abad, Wilfred FJ van IJcken, Niels Galjart, A Arockia Jeyaprakash, Helder Maiato, Cristina Ferrás
Publikováno v:
eLife, Vol 7 (2018)
Recent studies have challenged the prevailing dogma that transcription is repressed during mitosis. Transcription was also proposed to sustain a robust spindle assembly checkpoint (SAC) response. Here, we used live-cell imaging of human cells, RNA-se
Externí odkaz:
https://doaj.org/article/c3856abb5ad74415bb65bc3b4e3502e2
Autor:
Ya Guo, Ediem Al-Jibury, Rosalba Garcia-Millan, Konstantinos Ntagiantas, James W.D. King, Alex J. Nash, Niels Galjart, Boris Lenhard, Daniel Rueckert, Amanda G. Fisher, Gunnar Pruessner, Matthias Merkenschlager
Publikováno v:
Molecular Cell, 82(20), 3769-3780.e5. Cell Press
Molecular Cell
3780.e5
Molecular Cell
3780.e5
Complex genomes show intricate organization in three-dimensional (3D) nuclear space. Current models posit that cohesin extrudes loops to form self-interacting domains delimited by the DNA binding protein CTCF. Here, we describe and quantitatively cha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c5b1f16784d57e760a66222bb598430
https://pure.eur.nl/en/publications/deb2b8ee-4dfb-4c73-8c7e-b2e8810350e7
https://pure.eur.nl/en/publications/deb2b8ee-4dfb-4c73-8c7e-b2e8810350e7
Autor:
Joachim Boers, Frank Sleutels, Enrique Vidal, Rainer Renkawitz, Frank Grosveld, Ruben Boers, Niels Galjart, Mirjam C G N van den Hout, Silvia C Hernandez, Wiggert A. van Cappellen, Sarra Merzouk, Adriaan B Houtsmuller, Gregoire Stik, Marek Bartkuhn, Michael van der Reijden, Joost Gribnau, Thomas Graf, Zeliha Ozgur, Sreya Basu, Ralph Stadhouders, Widia Soochit, Bart Geverts, Wilfred F. J. van IJcken
Publikováno v:
Dev Cell
Nature Cell Biology, 23(8), 881-893. Nature Publishing Group
Nature Cell Biology, 23(8), 881-893. Nature Publishing Group
The 11 zinc finger (ZF) protein CTCF regulates topologically associating domain formation and transcription through selective binding to thousands of genomic sites. Here, we replaced endogenous CTCF in mouse embryonic stem cells with green-fluorescen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74dfc5062424a1bb8d40df0bdfc26739
https://doi.org/10.1038/s41556-021-00722-w
https://doi.org/10.1038/s41556-021-00722-w