Výsledky vyhledávání - "Niek J Pluijmert"

Akademický článek

Discrepant Results of Experimental Human Mesenchymal Stromal Cell Therapy after Myocardial Infarction: Are Animal Models Robust Enough?

Autor: Melina C den Haan, Vanessa-Leigh van Zuylen, Niek J Pluijmert, Cindy I Schutte, Willem E Fibbe, Martin J Schalij, Helene Roelofs, Douwe E Atsma

Publikováno v: PLoS ONE, Vol 11, Iss 4, p e0152938 (2016)

Human mesenchymal stromal cells (MSCs) have been reported to preserve cardiac function in myocardial infarction (MI) models. Previously, we found a beneficial effect of intramyocardial injection of unstimulated human MSCs (uMSCs) on cardiac function

Externí odkaz: https://doaj.org/article/dc6cc5517a634a8fb5626ff0e404f174

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Akademický článek

Annexin A5 reduces infarct size and improves cardiac function after myocardial ischemia-reperfusion injury by suppression of the cardiac inflammatory response

Autor: Rob C. M. de Jong, Niek J. Pluijmert, Margreet R. de Vries, Knut Pettersson, Douwe E. Atsma, J. Wouter Jukema, Paul H. A. Quax

Publikováno v: Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)

Abstract Annexin A5 (AnxA5) is known to have anti-inflammatory and anti-apoptotic properties. Inflammation and apoptosis are key processes in post-ischemic cardiac remodeling. In this study, we investigated the effect of AnxA5 on left ventricular (LV

Externí odkaz: https://doaj.org/article/50bd8d889bfd42e0baca7bd420a4b082

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Phosphorylcholine antibodies restrict infarct size and left ventricular remodelling by attenuating the unreperfused post-ischaemic inflammatory response

Autor: Douwe E. Atsma, J. Wouter Jukema, Rob C. M. de Jong, Margreet R. de Vries, Niek J. Pluijmert, Paul H.A. Quax, Knut Pettersson

Publikováno v: Journal of Cellular and Molecular Medicine
Journal of Cellular and Molecular Medicine, 25(16), 7772-7782. WILEY
Journal of Cellular and Molecular Medicine, 25(16), 7772-7782. Wiley-Blackwell
Pluijmert, N J, de Jong, R C M, de Vries, M R, Pettersson, K, Atsma, D E, Jukema, J W & Quax, P H A 2021, ' Phosphorylcholine antibodies restrict infarct size and left ventricular remodelling by attenuating the unreperfused post-ischaemic inflammatory response ', Journal of Cellular and Molecular Medicine, vol. 25, no. 16, pp. 7772-7782 . https://doi.org/10.1111/jcmm.16662

Phosphorylcholine is a pro‐inflammatory epitope exposed on apoptotic cells, and phosphorylcholine monoclonal immunoglobulin (Ig)G antibodies (PC‐mAb) have anti‐inflammatory properties. In this study, we hypothesize that PC‐mAb treatment reduc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa823e92692cfc5104a63efc6e45d1ae
https://pubmed.ncbi.nlm.nih.gov/34190404

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Post-ischemic myocardial inflammatory response

Autor: Niek J. Pluijmert, Douwe E. Atsma, Paul H. A. Quax

Publikováno v: Frontiers in Cardiovascular Medicine
Frontiers in Cardiovascular Medicine, Vol 8 (2021)

Following acute occlusion of a coronary artery causing myocardial ischemia and implementing first-line treatment involving rapid reperfusion, a dynamic and balanced inflammatory response is initiated to repair and remove damaged cells. Paradoxically,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::094e7ecbf2ddf7a5fc7d761b51a4053a
https://doi.org/10.3389/fcvm.2021.647785

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Effects on cardiac function, remodeling and inflammation following myocardial ischemia–reperfusion injury or unreperfused myocardial infarction in hypercholesterolemic APOE*3-Leiden mice

Autor: Niek J. Pluijmert, Douwe E. Atsma, Cindy I. Bart, Wilhelmina H. Bax, Paul H.A. Quax

Publikováno v: Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Scientific Reports, 10(1). NATURE RESEARCH
Scientific Reports, 10(1). Nature Research

Many novel therapies to treat myocardial infarction (MI), yielding promising results in animal models, nowadays failed in clinical trials for several reasons. The most used animal MI model is based on permanent ligation of the left anterior descendin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::230237f619659a16f4631a4a350e17c7
http://europepmc.org/articles/PMC7538581

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Hypercholesterolemia affects cardiac function, infarct size and inflammation in APOE*3-Leiden mice following myocardial ischemia-reperfusion injury

Autor: Melina C. den Haan, Niek J. Pluijmert, Vanessa L. van Zuylen, Hetty C. de Boer, Anton J. van Zonneveld, Willem E. Fibbe, Paul H.A. Quax, Paul Steendijk, Douwe E. Atsma, Martin J. Schalij

Publikováno v: PLoS ONE
PLoS ONE, 14(6). PUBLIC LIBRARY SCIENCE
PLoS ONE, Vol 14, Iss 6, p e0217582 (2019)

BackgroundHypercholesterolemia is a major risk factor for ischemic heart disease including acute myocardial infarction. However, long-term effects of hypercholesterolemia in a rodent myocardial ischemia-reperfusion injury model are unknown. Therefore

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43704acef4bc6f2813dbcd0d0c09ef71
https://hdl.handle.net/1887/121986

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Annexin A5 reduces infarct size and improves cardiac function after myocardial ischemia-reperfusion injury by suppression of the cardiac inflammatory response

Autor: Niek J. Pluijmert, Margreet R. de Vries, J. Wouter Jukema, Paul H.A. Quax, Knut Pettersson, Rob C. M. de Jong, Douwe E. Atsma

Publikováno v: Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)
Scientific Reports
Scientific Reports, 8(1), 6753
Scientific Reports, 8

Annexin A5 (AnxA5) is known to have anti-inflammatory and anti-apoptotic properties. Inflammation and apoptosis are key processes in post-ischemic cardiac remodeling. In this study, we investigated the effect of AnxA5 on left ventricular (LV) functio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1a196889bcab7b287d9798e796fc81b
https://doi.org/10.1038/s41598-018-25143-y

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VISI Revisited

Autor: Niek J. Pluijmert

Publikováno v: Lecture Notes in Business Information Processing ISBN: 9783319579542

In this paper we investigate the use in practice of the VISI standard. The goal of the VISI standard is to arrange the cooperation of the parties in construction projects. Application of the VISI standard is not without troubles. The VISI standard is

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::406ae9e51e0b296b377d1ebf1abb0f90
https://doi.org/10.1007/978-3-319-57955-9_6

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