Interspecies conservation of organisation and function between nonhomologous regional centromeres

Autor: Tong, P, Pidoux, A, Toda, N, Ard, R, Berger, H, Shukla, M, Torres-Garcia, J, Müller, C, Nieduszynski, C, Allshire, R

Publikováno v: Nature Communications
Nature Communications, Nature Publishing Group, 2019, 10 (1), pp.(2019) 10:2343. ⟨10.1038/s41467-019-09824-4⟩
Tong, P, Pidoux, A, Toda, N R T, Ard, R, Berger, H, Shukla, M, Torres-Garcia, J, Mueller, C A, Nieduszynski, C A & Allshire, R C 2019, ' Interspecies conservation of organisation and function between nonhomologous regional centromeres ', Nature Communications, vol. 10, 2343 . https://doi.org/10.1038/s41467-019-09824-4
University of Copenhagen
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)

Despite the conserved essential function of centromeres, centromeric DNA itself is not conserved. The histone-H3 variant, CENP-A, is the epigenetic mark that specifies centromere identity. Paradoxically, CENP-A normally assembles on particular sequen

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Whole-genome analysis of animal A- and B-type cyclins

Autor: Nieduszynski, C. A., Murray, J., Mark Carrington

Publikováno v: Scopus-Elsevier
Genome Biology
ResearcherID

Multiple A- and B-type cyclins have been identified in animals, but their study is complicated by varying degrees of functional redundancy. A single functional A-type cyclin gene was found in invertebrates and two were found in vertebrates. The numbe

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Rif1 acts through Protein Phosphatase 1 but independent of replication timing to suppress telomere extension in budding yeast

Autor: Kedziora, S, Gali, V, Wilson, R, Clark, K, Nieduszynski, C, Hiraga, S, Donaldson, A

Publikováno v: Nucleic Acids Research

The Rif1 protein negatively regulates telomeric TG repeat length in the budding yeast Saccharomyces cerevisiae, but how it prevents telomere over-extension is unknown. Rif1 was recently shown to control DNA replication by acting as a Protein Phosphat

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