Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Nidhi Khattree"'
Autor:
Yagya V Sharma, Radu I Cojocaru, Linda M Ritter, Nidhi Khattree, Matthew Brooks, Alison Scott, Anand Swaroop, Andrew F X Goldberg
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e31371 (2012)
Inherited defects in retinal photoreceptor structure impair visual transduction, disrupt relationship with the retinal pigment epithelium (RPE), and compromise cell viability. A variety of progressive retinal degenerative diseases can result, and kno
Externí odkaz:
https://doaj.org/article/90ab2fc331f44d4fa2a526da284f3d96
Autor:
Andrew F.X. Goldberg, Nidhi Khattree, Orson L. Moritz, Linda M. Ritter, Frank Schmitz, Beatrice M. Tam
Publikováno v:
The Journal of Neuroscience. 31:11231-11243
Vertebrate photoreceptors initiate vision via a G-protein-mediated signaling cascade organized within a specialized cilium, the outer segment (OS). The membranous “stacked pancake” architecture of this organelle must be partially renewed daily to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d41e19cbe09236984376d173162e11c5
https://doi.org/10.1523/jneurosci.2875-11.2011
https://doi.org/10.1523/jneurosci.2875-11.2011
Publikováno v:
Journal of Biological Chemistry. 276:42700-42706
Peripherin/rds is an integral membrane protein required for the elaboration of rod and cone photoreceptor outer segments in the vertebrate retina; it causes a surprising variety of progressive retinal degenerations in humans and dysmorphic photorecep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6d9d049553f85c27f776c788902be6ec
https://doi.org/10.1074/jbc.m107511200
https://doi.org/10.1074/jbc.m107511200
Vertebrate vision requires photon absorption by photoreceptor outer segments (OSs), structurally elaborate membranous organelles derived from non-motile sensory cilia. The structure and function of OSs depends on a precise stacking of hundreds of mem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28e985b70402b031d76f95903687dbe0
https://europepmc.org/articles/PMC3795338/
https://europepmc.org/articles/PMC3795338/
Autor:
Sumi Dinda, Cliff Hurd, Nidhi Khattree, Suresh C. Jhanwar, Paul Alban, Koushik Nag, Virinder K. Moudgil
Publikováno v:
Journal of Biological Chemistry. 270:28507-28510
Under normal culturing conditions, the T47D human breast cancer cell line expresses progesterone receptor constitutively and is responsive to estrogen. Because the tumor suppressor protein p53 plays a central role in determining genetic stability and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9c90813c29897265fefcf2d76b89ad4
https://doi.org/10.1074/jbc.270.48.28507
https://doi.org/10.1074/jbc.270.48.28507
Autor:
Linda M, Ritter, Kathleen, Boesze-Battaglia, Beatrice M, Tam, Orson L, Moritz, Nidhi, Khattree, Shu-Chu, Chen, Andrew F X, Goldberg
Publikováno v:
The Journal of biological chemistry. 279(38)
Inherited defects in the RDS gene cause a multiplicity of progressive retinal diseases in humans. The gene product, peripherin/rds (P/rds), is a member of the tetraspanin protein family required for normal vertebrate photoreceptor outer segment (OS)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5744cb6b8f67898b4876f7ffe9f9a163
https://pubmed.ncbi.nlm.nih.gov/15252042
https://pubmed.ncbi.nlm.nih.gov/15252042
Publikováno v:
The Journal of steroid biochemistry and molecular biology. 76(1-5)
This laboratory is studying hormonal regulation of tumor suppressor proteins, p53 and retinoblastoma (pRB). Estrogen receptor and progesterone receptor positive human breast cancer cell lines, T47D and MCF-7, were utilized for determining influence o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e828c6d30d6e4408d36aacebf86d648c
https://pubmed.ncbi.nlm.nih.gov/11384868
https://pubmed.ncbi.nlm.nih.gov/11384868
Publikováno v:
The Journal of steroid biochemistry and molecular biology. 77(2-3)
Phosphorylation of the tumor suppressor protein, retinoblastoma (pRb), regulates the progression of the cell cycle. Previous work from this laboratory had shown that estradiol (E(2)) regulates tumor suppressor proteins, p53 and retinoblastoma in brea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1de9a1e0a82c5ecd9937e33341036206
https://pubmed.ncbi.nlm.nih.gov/11377979
https://pubmed.ncbi.nlm.nih.gov/11377979
Publikováno v:
Oncogene. 18(4)
Loss of p53 function by mutational inactivation is the most common marker of the cancerous phenotype. Previous studies from our laboratory have demonstrated 17 beta estradiol (E2) induction of p53 protein expression in breast cancer cells. Although d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5491fabc82de1cdc954af8ca43bc02fc
https://pubmed.ncbi.nlm.nih.gov/10023683
https://pubmed.ncbi.nlm.nih.gov/10023683
Publikováno v:
Oncogene. 15(8)
We have utilized the estrogen receptor (ER)-positive human breast carcinoma cell line, T47D, to determine the role of ER in regulating cell proliferation, the level of expression of p53 and the state of phosphorylation of retinoblastoma protein (pRB)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5042b5abd9ca02e9a8adf92c96f5e1b7
https://pubmed.ncbi.nlm.nih.gov/9285694
https://pubmed.ncbi.nlm.nih.gov/9285694