Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Nidhi Girish"'
Autor:
Shahbaz Ahmed, Mohammad Suhail Khan, Savitha Gayathri, Randhir Singh, Sahil Kumar, Unnatiben Rajeshbhai Patel, Sameer Kumar Malladi, Raju S. Rajmani, Petrus Jansen van Vuren, Shane Riddell, Sarah Goldie, Nidhi Girish, Poorvi Reddy, Aditya Upadhyaya, Suman Pandey, Samreen Siddiqui, Akansha Tyagi, Sujeet Jha, Rajesh Pandey, Oyahida Khatun, Rohan Narayan, Shashank Tripathi, Alexander J. McAuley, Nagendrakumar Balasubramanian Singanallur, Seshadri S. Vasan, Rajesh P. Ringe, Raghavan Varadarajan
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Saturation suppressor mutagenesis was used to generate thermostable mutants of the SARS-CoV-2 spike receptor-binding domain (RBD). A triple mutant with an increase in thermal melting temperature of ~7°C with respect to the wild-type B.1 RBD and was
Externí odkaz:
https://doaj.org/article/f5b173c45f564f3cb20fc74fc1645467
Autor:
Shashank Tripathi, Somnath Dutta, Nagendrakumar Balasubramanian Singanallur, Ishika Pramanick, Sujeet Jha, Aditya Upadhyaya, Unnatiben Rajeshbhai Patel, Sankar Bhattacharyya, Parismita Kalita, Rajesh P. Ringe, Akansha Tyagi, Nidhi Girish, Shane Riddell, Sara Khaleeq, Debajyoti Chakraborty, Poorvi Reddy, Mohammad Suhail Khan, Raghavan Varadarajan, Samreen Siddiqui, Nupur Agarwal, Sameer Kumar Malladi, Kawkab Kanjo, Madhuraj Bhat, Shailendra Mani, Sarah Goldie, Savitha Gayathri, Suman Pandey, R. S. Rajmani, Sahil Kumar, Rajesh Pandey, Randhir Singh, Petrus Jansen van Vuren, Alexander J. McAuley, Seshadri S. Vasan
Publikováno v:
ACS infectious diseases. 7(8)
The Receptor Binding Domain (RBD) of SARS-CoV-2 is the primary target of neutralizing antibodies. We designed a trimeric, highly thermotolerant glycan engineered RBD by fusion to a heterologous, poorly immunogenic disulfide linked trimerization domai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::445b1f6677b6acfbbbf89f39b666f062
https://pubmed.ncbi.nlm.nih.gov/34260218
https://pubmed.ncbi.nlm.nih.gov/34260218
Autor:
Nayanika Sengupta, Suman Mishra, Somnath Dutta, Alakta Das, Nidhi Girish, Suman Pandey, Ishika Pramanick
Publikováno v:
Structure (London, England : 1993)
Spike (S) glycoprotein of SARS-CoV2 exists chiefly in two conformations, open and closed. Most previous structural studies on S protein have been conducted at pH 8.0, but knowledge of the conformational propensities under both physiological and endos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ca806e8f1c04c8c19faf0399108f413
https://pubmed.ncbi.nlm.nih.gov/33932324
https://pubmed.ncbi.nlm.nih.gov/33932324
Autor:
Aditya Upadhyaya, Ishika Pramanick, Mohammad Suhail Khan, Sameer Kumar Malladi, Parismita Kalita, Gautham Nadig, Kawkab Kanjo, Suvankar Dutta, Karthika Thankamani, Raghavan Varadarajan, Savitha Gayathri, Nidhi Girish, Shailendra Mani, Reman K. Singh, Syed Moiz Ahmed, Sankar Bhattacharyya, Jeswin Joseph, M. K. Bhasin, Raj Vs, Suman Pandey, Poorvi Reddy
Virtually all SARS-CoV-2 vaccines currently in clinical testing are stored in a refrigerated or frozen state prior to use. This is a major impediment to deployment in resource-poor settings. Several use viral vectors or mRNA. In contrast to protein s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::47992898efed5573b75e0928184026e8
https://doi.org/10.1101/2020.08.15.252437
https://doi.org/10.1101/2020.08.15.252437
Autor:
Shahbaz Ahmed, Kawkab Kanjo, Somnath Dutta, Ishika Pramanick, Nidhi Girish, Parismita Kalita, Aditya Upadhyaya, Sankar Bhattacharyya, Poorvi Reddy, Karthika Thankamani, M. K. Bhasin, Mohammad Suhail Khan, Randhir Singh, Savitha Gayathri, V. Stalin Raj, Sameer Kumar Malladi, Suman Pandey, Shailendra Mani, Jeswin Joseph, Raghavan Varadarajan, Gautham Nadig, Ramandeep Singh
Publikováno v:
The Journal of Biological Chemistry
Journal of Biological Chemistry
Journal of Biological Chemistry
Virtually all SARS-CoV-2 vaccines currently in clinical testing are stored in a refrigerated or frozen state prior to use. This is a major impediment to deployment in resource-poor settings. Furthermore, several of them use viral vectors or mRNA. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33efa7e34e72337f402627e1a3fedab6
https://doi.org/10.1074/jbc.ra120.016284
https://doi.org/10.1074/jbc.ra120.016284