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Autor:
Costanza Lo Cascio, Tigran Margaryan, Ernesto Luna Melendez, James McNamara, William Knight, Connor White, Zorana Opachich, Niddhi Ganta, Alexis Giff, Nader Sanai, Artak Tovmasyan, Shwetal Mehta
Publikováno v:
Neuro-Oncology. 24:vii216-vii216
Glioblastoma (GBM) is characterized by an aberrant yet druggable epigenetic landscape. Class I HDACs mediate chromatin compaction and are frequently overexpressed in GBM. Hence, there has been considerable interest in HDAC inhibitors (HDACi) for the