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of 4
pro vyhledávání: '"Nidda F. Waraich"'
Autor:
Nidda F Waraich, Shruti Jain, Sean D Colloms, William Marshall Stark, Nicolas P Burton, Anthony Maxwell
Publikováno v:
BioTechniques, Vol 69, Iss 5, Pp 356-362 (2020)
Decatenation is a crucial in vivo reaction of DNA topoisomerases in DNA replication and is frequently used in in vitro drug screening. Usually this reaction is monitored using kinetoplast DNA as a substrate, although this assay has several limitation
Externí odkaz:
https://doaj.org/article/b15a6bd41f074999a199dd2cfe105613
Autor:
William Marshall Stark, Anthony Maxwell, Shruti Jain, Sean D. Colloms, Nidda F. Waraich, Nicolas P. Burton
Decatenation is a crucial in vivo reaction of DNA topoisomerases in DNA replication and is frequently used in in vitro drug screening. Usually this reaction is monitored using kinetoplast DNA as a substrate, although this assay has several limitation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93f77721dbf8e307db205b664a40fae7
https://eprints.gla.ac.uk/278808/1/278808.pdf
https://eprints.gla.ac.uk/278808/1/278808.pdf
Publikováno v:
The Biochemist. 40:26-31
DNA topoisomerases have been described as ‘the magicians of the DNA world’, somehow allowing DNA strands to pass through each other. These ingenious enzymes are both essential and potentially dangerous, as any interruption in their DNA breakage-r
Autor:
Nidda F. Waraich, Maxime G. Corral, Aleksandra W. Debowski, Michael D. Wallace, Anthony Maxwell, Keith A. Stubbs, Joshua S. Mylne
Publikováno v:
Chemical communications (Cambridge, England). 54(15)
Ciprofloxacin has been shown to exhibit potent herbicidal activity through action against plant DNA gyrase, presenting a novel mode of action. Analogues of ciprofloxacin have been prepared with increased herbicidal activity and diminished antibacteri