Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Nidal E Muvarak"'
Autor:
Maria R. Baer, Eun Yong Choi, Nidal E Muvarak, Zeba N. Singh, Michael M. Seidman, Pratik K. Nagaria, Tyler Rutherford, Feyruz V. Rassool, Søren M. Bentzen, Rena G. Lapidus, Limin Xia, Yi Cai, Ying Zou, Marina A. Bellani, Stephen B. Baylin, Khadiza Chowdhury, Vu H. Duong, Carine Robert
Poly (ADP-ribose) polymerase inhibitors (PARPis) are clinically effective predominantly for BRCA-mutant tumors. We introduce a mechanism-based strategy to enhance PARPi efficacy based on DNA damage-related binding between DNA methyltransferases (DNMT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b439e03d8623240be3321961e7b1af7f
https://europepmc.org/articles/PMC5201166/
https://europepmc.org/articles/PMC5201166/
Publikováno v:
American journal of physiology. Heart and circulatory physiology. 288(3)
Right heart failure due to pulmonary hypertension causes significant morbidity and mortality. To study the linked vascular mechanical and biological changes that are induced by pulmonary hypertension, we mechanically tested isolated left main pulmona
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::700b7f4b382b51a264745112de82c1fd
https://pubmed.ncbi.nlm.nih.gov/15528223
https://pubmed.ncbi.nlm.nih.gov/15528223
Publikováno v:
Advances in Bioengineering.
Hypobaric hypoxia produces pulmonary hypertension in mice which causes pulmonary vascular remodeling. To study the biomechanics of this process, mice were exposed to hypoxia for 0-(control), 10-, and 15-days. Using a pressurized arteriograph system,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a02e0eaf3bd79ae158296b156b4074f4
https://doi.org/10.1115/imece2003-43086
https://doi.org/10.1115/imece2003-43086